35 results about "Absorbable Implants" patented technology

Two (or more), -component, body-implantable, absorbable, biocompatible, putty, and non-putty hemostatic tamponades for use in surgery. Component 1 is a finely powdered bulking material, preferably less than 50 microns, e.g. the calcium, magnesium, aluminum, or barium salts of saturated or unsaturated carboxylic acids containing about 6 to 22 carbon atoms, hydroxyapatite, DBM, polyglycolide, polylactide, poldioxinones, polycaprolactones, absorbable glasses, gelatin, collagens, mono, and polysaccharides starches. Component 2, a dispersing vehicle, may be esters unsubstituted and N-substituted pyrrolidones of C8-C18 monohydric alcohols with C2-C6 aliphatic monocarboxylic acids; C2-C18 monohydric alcohols with polycarboxylic acids; C8-C30 monohydric alcohols; tocopherol and esters thereof with C2-C10 aliphatic monocarboxylic acids or polycarboxylic acids; absorbable 10-14C hydrocarbons; free carboxylic acids such as oleic, capric, and lauric; dialkyl ethers and ketones; alkyl aryl ethers and ketones, polyhydroxy compounds and esters and ethers thereof; (ethylene oxide / propylene oxide copolymers), oils e.g. olive oil, castor oil and triglycerides.

Absorbable implants for breast surgery that conform to the breast parenchyma and surrounding chest wall have been developed. These implants support newly lifted breast parenchyma, and / or a breast implant. The implants have mechanical properties sufficient to support a reconstructed breast, and allow the in-growth of tissue into the implant as it degrades. The implants have a strength retention profile allowing the support of the breast to be transitioned from the implant to regenerated host tissue, without significant loss of support. Three-dimensional implants for use in minimally invasive mastopexy / breast reconstruction procedures are also described, that confer shape to a patient's breast. These implants are self-reinforced, can be temporarily deformed, implanted in a suitably dissected tissue plane, and resume their preformed three-dimensional shape. The implants are preferably made from poly-4-hydroxybutyrate (P4HB) and copolymers thereof. The implants have suture pullout strengths that can resist the mechanical loads exerted on the reconstructed breast.

Absorbable implants for breast surgery that conform to the breast parenchyma and surrounding chest wall have been developed. These implants support newly lifted breast parenchyma, and / or a breast implant. The implants have mechanical properties sufficient to support a reconstructed breast, and allow the ingrowth of tissue into the implant as it degrades. The implants have a strength retention profile allowing the support of the breast to be transitioned from the implant to regenerated host tissue, without significant loss of support. Three-dimensional implants for use in minimally invasive mastopexy / breast reconstruction procedures are also described, that confer shape to a patient's breast. These implants are self-reinforced, can be temporarily deformed, implanted in a suitably dissected tissue plane, and resume their preformed three-dimensional shape. The implants are preferably made from poly-4-hydroxybutyrate (P4HB) and copolymers thereof. The implants have suture pullout strengths that can resist the mechanical loads exerted on the reconstructed breast

The present application is directed to compositions and methods for mechanically controlling the bleeding of bone. The compositions comprise in intimate admixture the following Components 1, 2 and 3: (1) a finely powdered, carboxylic acid salt comprising a carboxylate anion and a metallic cation, (2) a composition comprising pyrrolidone or an N-alkyl pyrrolidone wherein alkyl is a C1-C12 alkyl radical and an optional, biocompatible liquefying agent if the composition is in solid form at room temperature, and (3) an optional analgesic, wherein the analgesic is present in a free base and salt form.

Full contour absorbable implants for breast surgery redistribute breast volume between the breast's upper and lower poles in exact and desirable ratios. The implants preferably redistribute breast volume so that the upper pole breast volume is 20-40% of the total volume, and the lower pole breast volume is 60-80% of the total volume. The implants are also designed to provide specific curvatures to the poles of the breast, and to angulate the nipple areolar complex slightly skyward so that the patient's nipple is positioned at an angle above the nipple meridian reference line. The implants are designed to be transitory, with sufficient strength retention to allow transition from support of the breast by the implant to support by regenerated host tissue growing in and around the implants, without any significant loss of support during or subsequent to remodeling. The implants may optionally be used with permanent breast implants.

The present invention relates to mechanically hemostatic body-absorbable compositions having a putty-like consistency comprising a finely powdered polysaccharide and a biocompatible liquid comprising one or more block copolymers of ethylene oxide and propylene oxide.

An absorbable implant comprises a basic compound made of a material which can be absorbed by the body of the implant recipient. A coating which contains titanium partially covers the basic compound, so that the latter comprises coating-free zones for the body to engage and absorb.

Two (or more), -component, body-implantable, absorbable, biocompatible, putty, and non-putty hemostatic tamponades for use in surgery. Component 1 is a finely powdered bulking material, preferably less than 50 microns, e.g. the calcium, magnesium, aluminum, or barium salts of saturated or unsaturated carboxylic acids containing about 6 to 22 carbon atoms, hydroxyapatite, DBM, polyglycolide, polylactide, polydioxinones, polycaprolactones, absorbable glasses, gelatin, collagens, mono, and polysaccharides starches. Component 2, a dispersing vehicle, may be esters of C8-C18 monohydric alcohols with C2-C6 aliphatic monocarboxylic acids; C2-C18 monohydric alcohols with polycarboxylic acids; C8-C30 monohydric alcohols; tocopherol and esters thereof with C2-C10 aliphatic monocarboxylic acids or polycarboxylic acids; absorbable 10-14C hydrocarbons; free carboxylic acids such as oleic, capric, and lauric; dialkyl ethers and ketones; alkyl aryl ethers and ketones, polyhydroxy compounds and esters and ethers thereof; (ethylene oxide / propylene oxide copolymers), oils e.g. olive oil, castor oil and triglycerides.

Full contour absorbable implants for breast surgery redistribute breast volume between the breast's upper and lower poles in exact and desirable ratios. The implants preferably redistribute breast volume so that the upper pole breast volume is 20-40% of the total volume, and the lower pole breast volume is 60-80% of the total volume. The implants are also designed to provide specific curvatures to the poles of the breast, and to angulate the nipple areolar complex slightly skyward so that the patient's nipple is positioned at an angle above the nipple meridian reference line. The implants are designed to be transitory, with sufficient strength retention to allow transition from support of the breast by the implant to support by regenerated host tissue growing in and around the implants, without any significant loss of support during or subsequent to remodeling. The implants may optionally be used with permanent breast implants.

The production of microstructured surfaces in magnesium alloys, containing zinc as the major alloying element, in particular in absorbable implants such as stents, wherein microstructures in sizes of up to 5 μm (micrometers) are generated on a magnesium alloy base body of the absorbable implant, for example of the absorbable stent, by way of optionally combined, pickling and electrochemical micropolishing processes, and allow better adhesion of a polymer coating (including higher break resistance) and higher corrosion resistance. The microstructured surface is produced out of the bulk material and exhibits no delamination from the base material during the mechanical deformation of the implant.

The present invention is directed to a biodegradable alloy suitable for use in a medical implant, comprising at least 50% iron by weight, at least 25% manganese by weight, and at least 0.01% sulfur and / or selenium by weight, wherein the biodegradable alloy is nonmagnetic. The present invention also provides a method of producing a biodegradable alloy with a desirable degradation rate.

The present invention relates to mechanically hemostatic body-absorbable compositions having a putty-like consistency. The compositions preferably comprise a finely powdered, carboxylic acid salt and a liquid block copolymer of ethylene oxide and propylene oxide.

The present invention relates to a ligament fixation system comprising a suspension plate and an absorbable implant and a method of use thereof. The ligament fixation system includes a suspension plate, an absorbable implant, a suspension wire, and a suture. The implant is cylindrical, with symmetrically distributed parallel openings around it, an arc-shaped groove forming a smooth connection with the ligament graft on the upper side, and a square groove convenient for suture fixing on the lower side. The implant increases the contact area between the ligament graft and the bone tunnel surface, hinders the penetration of joint fluid into the bone tunnel, effectively reduces the "wiper effect" and prevents the frictional fracture of the ligament graft. The use of absorbable materials facilitates true tendon‑bone healing. The ligament fixation system has wide sources of raw materials, is convenient to manufacture, is quick to assemble, and is simple to use, can simplify tendon treatment steps, shorten operation time, and significantly improve the firmness of ligament grafts.

The present disclosure is directed, in part, to a curable composition, a method for augmenting a structure in a patient with a resorbable biocompatible polymer, and a biodegradable, resorbable implant comprising a biocompatible copolymer. An exemplary embodiment of the curable composition comprises (a) 60 wt. % to 95 wt. % of one or more vinyl ester monomers and / or vinylcarbonate monomers, wherein said one or more vinyl ester monomers and / or vinylcarbonate monomers are respectively selected from compounds of the general formulas (I) and (II) below:wherein n, m R1 and R2 have the meaning defined herein; (b) 0.1 to 40 wt. % of one or more multifunctional thiols; and (c) 0 to 10 wt. % of a biocompatible polymerization initiator.

An implantable tissue filler including a particulate material suspended in a carrier, the particulate material having more than about 70% by weight magnesium and about 2-20% by weight lithium, wherein the particulate material is substantially free of rare earth metals.

The invention discloses a surface modification method of a bio-absorbable material implanted in a polyester, and the bio-absorbable material implanted in the polyester is treated by supercritical fluid. The invention utilizes the supercritical carbon dioxide technology to modify the surface of various existing internally absorbable implanted materials, so as to form holes with nanometer size or micron size on the surface of the material, the invention solves the problem that the interface of existing internally absorbable implanted material is not suitable for cell adhesion and proliferation, thereby facilitating protein adsorption and deposition of extracellular matrix, and integration with the surrounding tissues; moreover, the invention can form tiny blood vessels timely, and can achieve good synchronization of material degradation and replacement of bone cells.

The present invention relates to an absorbable implant material composed of magnesium or a magnesium alloy and to a method for the production thereof. A disadvantage of the known absorbable implants is that the position of the implant during the medical implantation procedure and immediately thereafter can only be tracked by means of X-ray examinations. According to the invention, the absorbable implant material comprising homogeneously distributed Fe-doped nanodiamonds in a matrix composed of magnesium or the magnesium alloy, is provided. The Fe-doped nanodiamonds are harmless to organisms soas to allow the detection of the implant material in the blood plasma of the patient by means of magnetic resonance imaging. According to the invention, the absorbable implant material according to the invention is produced by a method in which the magnesium or the magnesium alloy is melted, the Fe-doped nanodiamonds are added to a melt, and the melt composed of the magnesium or the magnesium alloy that has been provided with Fe-doped nanodiamonds is subjected to an ultrasound treatment.

The invention belongs to the field of medical instrument sterilization, and relates to a sterilization method for an absorbable implant and matched instrument combined product. The method comprises the following steps: cleaning non-absorbable instrument sub-components in a clean room, assembling into a non-absorbable matched instrument, carrying out ethylene oxide sterilization or radiation sterilization on the non-absorbable matched instrument, assembling the absorbable implant consumables on the sterilized non-absorbable matched instrument in a clean room, and then performing ethylene oxide sterilization and desorption. By adopting the method provided by the invention, the contradictions that the absorbable implant consumables in the absorbable implant and the matched instrument combined product cannot be subjected to excessive sterilization due to the characteristic of easy degradation and the sterilization effect cannot be ensured due to the complex structure of the non-absorbable matched instrument can be effectively solved; and the method can guarantee that the absorbable implant consumables and matched instruments with complex structures can achieve the sterile effect at the same time, the performance of the absorbable implant consumables cannot be reduced, and important practical use value and significance are achieved.

An amphiphilic organic sulfate, sulfamate, sulfonate, disulfate, disulfonate or trisulfonate is included in an aminoglycoside, lincosamide, 4-quinolone or tetracycline antibiotic preparation to retard the release of the antibiotic from the preparation. An antibiotic preparation comprises a mixture of an amphiphilic component consisting of one or more alkyl, aryl, alkylaryl, cycloalkyl or alkylcycloalkyl sulfates, sulfamates or sulfonates, fatty acid-2-sulfonates, alkyl or cycloalkyl disulfates, alkyl, cycloalkyl, aryl or alkylaryl disulfonates or aryl or alkylaryl trisulfonates and one or more aminoglycoside, lincosamide, 4-quinolone or tetracycline antibiotics.