The invention relates to a sealing arrangement for sealing and guiding a powered window pane (40), particularly of a motor vehicle. Said sealing arrangement is provided with a seal (20) produced as a single part from an elastically deformable material. The inventive sealing arrangement is also provided with a sash (10) which frames the window pane (40) and to which the seal (20) can be fixed. Said sash (10) comprises an inner flange (11) and an outer flange (12). The seal (20) comprises an inner side section (21) that can be fixed to the inner flange (11), an outer side section (22) that can be fixed to the outer flange (12), and a base portion (23) located outside the cavity portion (13). The aim of the invention is to achieve a universal embodiment of the seal (20). To this end, an inner sealing element (25) arranged on the inner leg portion (21), and an outer sealing element (26) arranged on the outer leg portion (22), are respectively embodied as a hollow chamber and provided with a contact surface area (29, 30) that can be applied to a side surface (41, 42) of the window pane (40). Said contact surface areas (29, 30) are embodied in two directions (x, y) extending perpendicularly in relation to each other, in such a way that the window pane (40) can be reversibly displaced between the inner sealing element (25) an the outer sealing element (26).