276results about How to "Resilience" patented technology

A device 10 and method for replacing or restoring competence to incompetent valves. The device 10 is inserted percutaneously or surgically and is preferably constructed of a material capable of promoting cellular ingrowth such that, eventually, native biologic tissue completely covers the device 10 insulating the blood flow therefrom. The material is preferably bioabsorbable over time, allowing the device to harbor the regeneration of a valve structure and to later become absorbed by the body. The device is sized and arranged to mimic the valve it is replacing or repairing.

A surgical port comprising a body and first and second cannula extending from the body and movable with respect to the body via an instrument inserted through the respective cannula. The cannulas can extend distally from the body and can include one or more seals. A port assembly and first and second instruments manipulatable in a crossed configuration are also disclosed.

An EMI shielding spacer gasket assembly for interposition under a predetermined compressive load within an electronics enclosure between a first surface and an oppositely-disposed second surface of the enclosure. The assembly includes a frame member and an electrically conductive, elastomeric member extending along at least a portion of the perimeter of the frame member as retained on a corresponding peripheral edge surface thereof. The elastomeric member has an outboard side which is compressible axially under the compressive load for providing an electrically conductive pathway between the surfaces of the enclosure. In an uncompressed orientation, the outboard side of the elastomeric member exhibits elongate upper and lower bearing portions which are disposed at a spaced-apart radial distance from the frame member to define a corresponding bending moment arm. Each of the bearing portions is angularly deflectable relative to the moment arm to effect the compression of the elastomeric member under a relatively low compressive load.

An object of the present invention is to provide a battery of high capacity that is excellent in storage, load, cycle, and continuous charge characteristics and that reduces gas generation; and a nonaqueous electrolyte for use in the battery. The invention relates to a nonaqueous electrolyte which comprises a nonaqueous organic solvent and a lithium salt dissolved therein, wherein the nonaqueous organic solvent contains at least one compound selected from the group consisting of acid anhydrides and carbonic esters having an unsaturated bond, and at least one compound selected from the group consisting of sulfonic compounds and fluorine-containing aromatic compounds having 9 carbon atoms or less; and a lithium secondary battery employing the same.

Disclosed herein a prosthetic or orthotic device having a joint portion and a compliant transmission assembly in operational communication with the joint portion. The device restores the normal capabilities and natural dynamics of a healthy joint for common activities. The compliant transmission assembly includes a compliant element. The compliant transmission assembly absorbs energy when a torque is applied. between a prosthetic or orthotic device portion and another adjacent device portion or the adjacent limb segment, of the user. The compliant element of the invention absorbs energy during flexion of a joint for the dampening thereof and releases this energy during extension of the joint for assistance thereof. Also disclosed herein is an actuator assembly, a torque sensor and an actuator locking device as well as a method for determining the torque of such prosthetic and orthotic devices.

The present invention is a system for delivering insulin to a subject to improve impaired hepatic glucose processing. The system delivers a series of pulses of insulin to the subject over a period of time accompanied by ingestion of glucose in the form of a carbohydrate containing meal. The amount of insulin in each pulse, the interval between pulses and the amount of time to deliver each pulse to the subject are selected so that the hepatic processing of glucose is restored in the subject. In subjects whose hepatic glucose processing has been restored there is a subsequent fall in circulating blood glucose levels of 50 mg / dl or more directly as a result of improved hepatic glucose processing.

A prior to charge vanadium halide redox cell, a vanadium halide redox cell which is at a state of charge selected from the group consisting of a zero state of charge and a near zero state of charge and vanadium halide redox cell which are fully charged and partially charged are described. The prior to charge vanadium halide redox cell comprises a positive half cell containing a positive half cell solution comprising a halide electrolyte, vanadium (III) halide and vanadium (IV) halide, a negative half cell containing a negative half cell solution comprising a halide electrolyte, vanadium (III) halide and vanadium (N) halide wherein the amounts of vanadium (III) halide, vanadium (IV) halide and halide ions in the positive and negative half cell solutions are such that in a first charging step comprising charging the prior to charge vanadium halide redox cell, a vanadium halide redox cell having a state of charge selected from the group consisting of a zero state of charge and a near zero state of charge comprising predominantly vanadium (N) halide in the positive half cell solution and predominantly V(III) halide in the negative half cell solution can be prepared. The vanadium halide redox cell which is at a state of charge selected from the group consisting of a zero state of charge and a near zero state of charge comprises a positive half cell containing a positive half cell solution comprising a halide electrolyte and a vanadium halide which is predominantly vanadium (N) halide, a negative half cell containing a negative half cell solution comprising a halide electrolyte and a vanadium halide which is predominantly vanadium (III) halide wherein the amount of vanadium (N) halide in the positive half cell solution and the amount of vanadium (III) halide in the negative half cell solution are such that the vanadium halide redox cell is at a state of charge selected from the group consisting of a zero state of charge and a near zero state of charge. The vanadium halide redox cell which is fully charged comprises a positive half cell containing a positive half cell solution comprising a halide electrolyte, a polyhalide complex, vanadium (IV) halide and vanadium (V) halide, a negative half cell containing a negative half cell solution comprising a halide electrolyte and vanadium (II) halide wherein the molar concentration of vanadium (V) and polyhalide complex:molar concentration of vanadium (II) halide is about stoichiometrically balanced. The vanadium halide redox cell which is partially charged comprises a positive half cell containing a positive half cell solution comprising a halide electrolyte, a polyhalide complex, vanadium (IV) halide and vanadium (V) halide, a negative half cell containing a negative half cell solution comprising a halide electrolyte, vanadium (II) halide and vanadium (III) halide wherein the number of moles of moles of polyhalide complex and vanadium (V): number of moles of vanadium (II) halide is about stoichiometrically balanced.

This invention is directed to advanced hemorrhage control wound dressings, and methods of using a producing same. The subject wound dressing is constructed from a non-mammalian material for control of severe bleeding. The wound dressing is formed of a biomaterial comprising chitosan for controlling severe bleeding. The kind of severe, life-threatening bleeding contemplated by this invention is typically of the type not capable of being stanched when a conventional gauze wound dressing is applied with conventional pressure to the subject wound. The wound dressing being capable of substantially stanching the flow of the severe life-threatening bleeding from the wound by adhering to the wound site, to seal the wound, to accelerate blood clot formation at the wound site, to reinforce clot information at the wound site and prevent bleed out from the wound site, and to substantially prohibit the flow of blood out of the wound site.

Specific sequences in the human genome are the sites of strong binding of wild-type p53 protein, but not mutant forms of the protein. These sequences are used diagnostically to detect cells in which the amount of wild-type p53 is diminished. The sequences can also be used to screen for agents which correct for loss of wild-type p53 to DNA in cancer cells.

Adjustment risers for use in a manhole or catch basin, between a lower support structure, for example, a concrete riser, and an upper frame assembly, adjacent a surface in which the hole is formed, have a molded body and typically are annular; one or more ribs extend outwardly from a first sealing face and a corresponding one or more grooves are formed in an opposed second sealing face, each groove being in opposed relationship with a rib, whereby the adjustment risers may be matingly stacked to provide a required adjustment riser height for a specified manhole or catch basin.

There is disclosed an absorbent article including an absorbent layer and a liquid-permeable surface sheet placed on a liquid-receiving side of the absorbent layer for introducing excreted liquid from the human body to the absorbent layer. The surface sheet is of a corrugated configuration to have valleys and peaks extending in a longitudinal direction of the article and alternately arranged in a transverse direction perpendicular to the longitudinal direction. Each valley has a connecting part raised to connect between two adjacent peaks.

A head acoustic device and a sound channel reproducing method discloses a multichannel acoustic device, especially a headset-multichannel acoustic device applying bone conduction speaker and a sound channel reproducing method. The headset-multichannel acoustic device of this invention includes a supporting frame and a vibration device on the frame, in which, the vibration device is a bone conduction speaker. The advantage of the present invention is that the sense of personally on the scene can be got by using the multichannel surround acoustic technology or by using the bone conduction speakers on different positions of bone and multichannel acoustic technology. On the other hand, it enables people with hearing handicap recover the ability of hearing music.

The invention provides a surface sizing solution used in the papermaking field. The surface sizing solution contains a product and water, the product is obtained after a cross-linking reaction of nano fibrillated cellulose, starch and a cross-linking agent, the nano fibrillated cellulose is single microfibrils of cellulose having a length of 100-2000nm and a diameter of 3-200nm obtained through defibrating cellulose raw materials, wherein bone dry mass parts of the nano fibrillated cellulose, the starch and the cross-linking agent are 0.1-10, 85-99.75 and 0.15-5 respectively. The invention also provides a sized paper made by using the surface sizing solution. The surface sizing surface containing the nano fibrillated cellulose is coated on the surface of paper to realize enforcing and toughening effects in order to effectively improve the flexibility resistance of the sized paper.

This invention relates to a method of reducing cardiovascular morbidity and mortality in a prediabetic or Type 2 Diabetes patient population. The method comprises administering an effective dosage of a long acting insulin, preferably insulin glargine, to a prediabetic or Type 2 Diabetes patient.

A skin care composition is useful for augmenting cellular metabolism in skin cells and thereby enhancing the regulation of intracellular signaling. The composition comprises a primer for skin cell mitochondrial function, such as a Krebs cycle intermediate, a precursor of a Krebs cycle intermediate, salts or esters thereof, or combinations thereof. The composition may also include antioxidants for free radical regulation and a pharmaceutically acceptable topical vehicle, such as an emollient base for skin health. A method for stimulating the mitochondrial activity of skin cells comprises administering to the skin of a person in need thereof a composition as described herein.

A generic structure for the peptides of the present invention includes A-X-B-C, where C is a cargo moiety, the B portion includes basic amino acids, X is a cleavable linker sequence, and the A portion includes acidic amino acids. The intact structure is not significantly taken up by cells; however, upon extracellular cleavage of X, the B-C portion is taken up, delivering the cargo to targeted cells. Cargo may be, for example, a contrast agent for diagnostic imaging, a chemotherapeutic drug, or a radiation-sensitizer for therapy. Cleavage of X allows separation of A from B, unmasking the normal ability of the basic amino acids in B to drag cargo C into cells near the cleavage event. X is cleaved extracellularly, preferably under physiological conditions. D-amino acids are preferred for the A and B portions, to minimize immunogenicity and nonspecific cleavage by background peptidases or proteases.

An organic biofertilizer is prepared from the excrement and urine of animals, water hyacinth, and duckwed and / or straw (stalk) and / or saw dust through proportional mixing and fermenting. It is rich in N,P,K and other necessary elements.

The present invention relates to a pharmaceutical composition comprising a GLP-1 derivative having a lipophilic substituent; and a surfactant.

A tubular membrane module and its method of manufacture are disclosed wherein tubular membranes form an interference self-sealing fit with hard tube sheets with the aid of a hard hollow mandrel inserted at the end of the tubular membranes. The tubular membranes are comprised of porous, compressible PTFE and / or fluorocopolymers. The self-sealing method described herein requires no heat treatment, allows for ease of manufacture without destruction of the tubular membranes and without the processing complexity of utilizing any additional potting agent, extrusion, or chemical cross-linking of any polymeric adhesives. The self sealing PTFE tubular membranes have superb chemical resistance and temperature resistance, and through the benefits of this invention, offer higher pull-out resistance than typically observed with potting materials such as polyurethane and epoxy. In addition, the self-sealing method is reversible and non-destructive (whereas chemical potting and sealing methods using heat are not), as one can easily remove one or more damaged tubes and replace them.

The invention relates to a nonaqueous electrolyte which comprises a nonaqueous organic solvent and a lithium salt dissolved therein, wherein the nonaqueous organic solvent contains at least one compound selected from the group consisting of acid anhydrides and carbonic esters having an unsaturated bond, and at least one compound selected from the group consisting of sulfonic compounds and fluorine-containing aromatic compounds having 9 carbon atoms or less; and a lithium secondary battery employing the same.

The invention discloses a production method of fireproof middle and high voltage cables. The production method includes the following steps: sorting; wire drawing; annealing; conductor stranding; inner shielding layer, insulation layer and outer shielding layer co-extrusion and warping; metal shielding layer arranging; first wrapping tape layer lapping; cabling stranding and cabling wrapping tape layer lapping; oxygen isolation layer extrusion; package fireproof isolation layer extrusion; second wrapping tape layer lapping; metal armor layer lapping; third wrapping tape layer lapping and outer sheath layer extrusion. The middle and high voltage cables produced in the production method have good heat insulation effect when being paved on buildings, are improved in fireproof performance, can delay damage to a power system caused by fire disasters, natural disasters and other accidents, and gains time for rescue.

A fibre-reinforced composite structure includes a cut edge; an elastomeric cap covering the cut edge; and an adhesive sealant bonding the elastomeric cap to the cut edge. The fibre-reinforced composite structure is joined to a component and the elastomeric cap includes a generally Z or L-shaped cap with a web bonded to the cut edge of the fibre-reinforced structure and a flange bonded to the component and extending away from the fibre-reinforced structure.