The invention discloses an anti-counterfeiting off-site commodity transaction method and system. According to the anti-counterfeiting off-site commodity transaction method and system, an anti-counterfeiting commodity transaction network formed by an anti-counterfeiting commodity transaction system, a production management system, a commodity sales system, a storehouse management system and a commodity transporting system is established, a string of user-defined anti-counterfeiting information set by a consumer runs through the whole commodity circulation process, only the final consumer can identify the authenticity of a commodity by verifying the anti-counterfeiting information, and the probability of counterfeiting of the commodity is reduced; a barcode, personalized information and a logistics barcode are bound with an order, real-time monitoring of production, storage and circulation of the commodity is achieved, planning management and dispatching are achieved, working efficiency is improved, and meanwhile tracking of the commodity is achieved. According to the anti-counterfeiting off-site commodity transaction method and system, counterfeiting and adulteration of the commodity in the tail stage of circulation are eliminated for the final consumer. The anti-counterfeiting off-site commodity transaction method and system are suitable for but not limited to off-site shopping such as online shopping and teleshopping.