148results about How to "Maintain sensitivity" patented technology

The present invention provides a method and system for operating a wireless communication system in which received signals from a plurality of antennas are weighted and combined with a beam forming operation to form an output signal. The beam forming operation determines weights adjusted to increase a desired signal power in the output signal while reducing the power in the output signal of out-of-band components. In an embodiment of the present invention, beam forming operations are performed with maximal ratio combining (MRC). Alternatively, a constant modulus algorithm (CMA) can be used for beam forming operations. In an alternate embodiment, improved interference suppression is performed with a novel algorithm referred to as an interference nulling algorithm (INA). The INA receives an error signal which is 180° out of phase with a combination of the channels for individual antennas, referred to as the SUM channel. The error signal is determined by complex conjugate multiplication of the individual signals and a reference complex signal. It is desirable to simultaneously achieve diversity and combining gain and suppress the adjacent channel by combining the weight generation for MRC and that for INA, as described above, to generate antenna weights similar to those of MMSE combining.

Method and apparatus for training a system model with gain constraints. A method is disclosed for training a steady-state model, the model having an input and an output and a mapping layer for mapping the input to the output through a stored representation of a system. A training data set is provided having a set of input data u(t) and target output data y(t) representative of the operation of a system. The model is trained with a predetermined training algorithm which is constrained to maintain the sensitivity of the output with respect to the input substantially within user defined constraint bounds by iteratively minimizing an objective function as a function of a data objective and a constraint objective. The data objective has a data fitting learning rate and the constraint objective has constraint learning rate that are varied as a function of the values of the data objective and the constraint objective after selective iterative steps.

The invention discloses a small molecule probe based on nano-gold and aptamer and a preparation method of the small molecule probe. The small molecule probe comprises nano-gold particles, more than one type of sulfydryl modifying deoxyribonucleic acid (DNA) fragment assembled on the nano-gold particles and more than one type of aptamer which is marked by fluorescent groups, and at least a part of fragments of the more than one type of the aptamer are complemented and hybridized with the more than one type of sulfydryl modifying DNA group. The small molecule probe is short in detecting time, simple in operation, high in specificity, good in repeatability, high in accuracy, and the false positive result is effectively reduced. By means of the aptamer technology, a high detection sensibility is achieved, and various molecules can be simultaneously detected.

A system and method for automatically segmenting a computed tomography (CT) image of a patient's lung. The method includes the steps of segmenting the CT image to acquire one or more lung regions, intensity thresholding the lung regions to generate a mask region comprising high-intensity regions corresponding to anatomical structures within the lung regions, computing a Euclidean distance map of the mask region, performing watershed segmentation of the Euclidean distance map to generate one or more sub-regions, identifying a seed point for each sub region, growing candidate regions from the seed point of each sub-region, and classifying one or more candidate regions as a lung nodule based on one or more geometric features of the candidate regions.

An active sieve device for the isolation and characterization of bio-analytes is provided, comprising a substrate for supporting the bio-analytes. The substrate comprises a plurality of interconnections and a plurality of regions, each region comprising a hole and at least one electrode embedded in or located on the substrate and electrically associated with the hole. Each region further comprises at least one transistor integrated in the substrate and operably connected to the at least one electrode and to at least one of the plurality of interconnections.

A piezoelectric vibration gyro element formed by etching from a quartz substrate of a Z-plate, includes: a base portion, a pair of vibration arms for detection extending from the base portion toward both sides thereof in the direction of Y-axis, a pair of coupling arms extending from the base portion toward both sides thereof in the direction of X-axis, pairs of vibration arms for driving extending from the end portions of the coupling arms toward both sides thereof in the direction of Y-axis, four beams extending from the base portion, and support portions connected to the ends of the beams, which are all arranged on an XY plane; wherein the beams are extending in the directions of about 30° or about 60° with the X-axis as a reference.

In an inductively coupled radio frequency identification (RFID) system deployed in animal and livestock applications, reading system efficacy can be compromised by animal movement on, around, or near metal structures prone to producing sonic frequencies. Such is the case, for example, when a walk-by antenna is mounted at the entry door of a livestock transport trader, and animals transit on a metallic ramp and metallic trader floor. Associated with the observable acoustic noise are subtle disturbances in the magnetic field surrounding the antenna due to vibrating metal altering the reluctance of the antenna's magnetic field. This acoustic noise manifests itself as an electrical noise phenomenon that interferes with the signals of certain types of identification tags which rely on amplitude modulation. The detrimental effects of acoustic noise from metal structures can be mitigated by using a multi-loop antenna that limits the spatial distribution of the transmitted magnetic field and cancels close by magnetic field disturbances.

An optical probe assembly for conveying Raman pump light to a specimen and for conveying a Raman signature from the specimen to an optical spectrum analyzer, the optical probe assembly comprising a light guide, wherein the light guide comprises a core region and a surrounding cladding region, wherein the core region is constructed so as to minimize the creation of a relatively broadband spurious background noise signal when conveying the Raman pump light to the specimen, and the cladding region is constructed so as to satisfy the wave guiding reflection requirements of the Raman pump light and the Raman signature. A Raman spectroscopy system comprising: a laser for producing Raman pump light; an optical probe assembly for conveying the Raman pump light to a specimen and for conveying a Raman signature from the specimen to an optical spectrum analyzer, the optical probe assembly comprising a light guide, wherein the light guide comprises a core region and a surrounding cladding region, wherein the core region is constructed so as to minimize the creation of a relatively broadband spurious background noise signal when conveying the Raman pump light to the specimen, and the cladding region is constructed so as to satisfy wave guiding reflection requirements of the Raman pump light and the Raman signature; and an optical spectrum analyzer for receiving the Raman signature of a specimen and identifying and characterizing the specimen based upon the spectrum of the Raman signature. A method for conducting Raman spectroscopy comprising: producing Raman pump light; conveying the Raman pump light through an optical probe assembly to a specimen and conveying a Raman signature from the specimen through the optical probe assembly to an optical spectrum analyzer, the optical probe assembly comprising a light guide, wherein the light guide comprises a core region and a surrounding cladding region, wherein the core region is constructed so as to minimize the creation of a relatively broadband spurious background noise signal when conveying the Raman pump light to the specimen, and the cladding region is constructed so as to satisfy wave guiding reflection requirements of the Raman pump light and the Raman signature; and identifying and characterizing the specimen based upon the spectrum of the Raman signature.

A method and apparatus for maintaining sensitivity of a homodyne receiver over varying transmitter power levels is disclosed. The method includes adjusting output power levels of a transmitter driver. A bias supply voltage to the transmitter driver may be adjusted to adjust the output power levels. A control voltage to the transmitter driver may be adjusted to adjust the output power levels of the transmitter driver. A homodyne radio frequency tag reader may include the method.

Method and apparatus for training a system model with gain constraints. A method is disclosed for training a steady-state model, the model having an input and an output and a mapping layer for mapping the input to the output through a stored representation of a system. A training data set is provided having a set of input data u(t) and target output data y(t) representative of the operation of a system. The model is trained with a predetermined training algorithm which is constrained to maintain the sensitivity of the output with respect to the input substantially within user defined constraint bounds by iteratively minimizing an objective function as a function of a data objective and a constraint objective. The data objective has a data fitting learning rate and the constraint objective has constraint learning rate that are varied as a function of the values of the data objective and the constraint objective after selective iterative steps.

In an inductively coupled radio frequency identification (RFID) system deployed in animal and livestock applications, reading system efficacy can be compromised by animal movement on, around, or near metal structures prone to producing sonic frequencies. Such is the case, for example, when a walk-by antenna is mounted at the entry door of a livestock transport trader, and animals transit on a metallic ramp and metallic trader floor. Associated with the observable acoustic noise are subtle disturbances in the magnetic field surrounding the antenna due to vibrating metal altering the reluctance of the antenna's magnetic field. This acoustic noise manifests itself as an electrical noise phenomenon that interferes with the signals of certain types of identification tags which rely on amplitude modulation. The detrimental effects of acoustic noise from metal structures can be mitigated by using a multi-loop antenna that limits the spatial distribution of the transmitted magnetic field and cancels close by magnetic field disturbances.

This invention relates to enhancing sensitivity of cytotoxic drugs by targeting their interfering mechanisms induced in the tumor microenvironment which lead to drug resistance, using combinatorial therapy with carboxyamidotriazole orotate. Specific doses of cytotoxic drugs are titrated with carboxyamidotriazole orotate to improve the sensitivity and anticancer activity of cytotoxic drugs.