The invention discloses an electric operation mechanism of a grounding switch of an intermediate and low voltage switch cabinet and aims at solving the problem that the electric operation, the transmission and the positioning of the grounding switch of the existing high voltage switch cabinet are inaccurate. The electric operation mechanism comprises a motor and an operation large shaft; a mechanism box is arranged on the operation large shaft; the motor, a transmission gear, a clutch gear and a motor output gear are arranged in the mechanism box, a moving gear is arranged on the operation large shaft, the moving gear is meshed with the clutch gear, the clutch gear is coaxial with the transmission gear, and the transmission gear is connected with the motor by the motor output gear. The electric operation mechanism has the advantages of small mechanism size, few transmission links, small energy loss, great transmission force moment, smooth transmission and the like, and the electric operation mechanism simultaneously improves the accuracy of the control on the transmission and the positioning, and also has the manual and the electric clutch functions.