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A system and method for treating subcutaneous histological features without affecting adjacent tissues adversely employs microwave energy of selected power, frequency and duration to penetrate subcutaneous tissue and heat target areas with optimum doses to permanently affect the undesirable features. The frequency chosen preferentially interacts with the target as opposed to adjacent tissue, and the microwave energy is delivered as a short pulse causing minimal discomfort and side effects. By distributing microwave energy at the skin over an area and adjusting power and frequency, different conditions, such as hirsuitism and telangiectasia, can be effectively treated.

A nozzle for the application of a fluid to a passing substrate in a bead form. The nozzle has a portion of the nozzle tip removed, preferably an anterior or aft portion, such that an even bead of a preselected depth may be applied to a workpiece to provide a reliable sealing joint

The invention relates to expandable rubber bladders comprised of EPDM rubber for shaping and curing articles of conjugated diene-based elastomers such as pneumatic tires. The bladders are of a rubber composition comprised of resin cured EPDM rubber composition as a terpolymer of ethylene / propylene and a minor amount of a non-conjugated diene. The bladder composition may also contain castor oil, corn oil and / or soya-bean oil. The bladder composition may also contain at least one of graphite and polytetrafluoroethylene powder. Alternately, the EPDM-based bladder rubber composition may also contain a minor amount of a butyl-type of rubber. The invention also relates to a method of curing pneumatic rubber tires by utilizing such EPDM-based expandable rubber tire curing bladder in a tire curing press.

A method includes selectively controlling, at a computing device having a memory, initiation of a full garbage collection operation based on a total resource usage metric and a managed object metric. The managed object metric is based on objects managed by a runtime application.

A system and method for treating subcutaneous histological features without affecting adjacent tissues adversely employs microwave energy of selected power, frequency and duration to penetrate subcutaneous tissue and heat target areas with optimum doses to permanently affect the undesirable features. The frequency chosen preferentially interacts with the target as opposed to adjacent tissue, and the microwave energy is delivered as a short pulse causing minimal discomfort and side effects. By distributing microwave energy at the skin over an area and adjusting power and frequency, different conditions, such as hirsuitism and telangiectasia, can be effectively treated.

A wire grip comprising a stationary-side gripping portion provided with a body and having a substantially straight front shape, and a movable-side wire gripping portion arranged to face the stationary-side wire gripping portion and set movable back and forth with respect to the stationary-side wire gripping portion, whereby the linear object can be gripped between the stationary-side wire gripping portion and the movable-side wire gripping portion, wherein a first action portion for moving the movable-side wire gripping portion back and forth and a second action portion connected to the first action portion by a connecting rod are turnably attached at their individual ends to the body, wherein the other end of the first action portion and the other end of the second action portion are turnably attached to one end of the connection rod and an intermediate portion of the connection rod, respectively, wherein the other end of the connecting rod is pulled substantially parallel to the stationary-side wire gripping portion and the movable-side wire gripping portion so that the connecting rod, the second action portion and the first action portion are linked to act to move the movable-side wire gripping portion forward with respect to the stationary-side wire gripping portion.

An implantable drug-delivery sleeve for an elongate component of an implantable medical device. The sleeve includes a tubular substrate having a lumen configured to receive the elongate component so as to allow relative displacement of the substrate and the elongate component, wherein the substrate is shaped so as to be retained stationary at a desired position along the elongate component, and a drug releasably carried by the substrate.

The present invention relates to a composition and method for remediation of heavy metal contaminated substances. More particularly, the present invention relates to a composition and method for remediating soil, paint chips, paint dusts, surfaces, and other substances contaminated with heavy metals by application of an aqueous suspension of phosphate compound. Even more particularly, the present invention relates to remediating soil, paint chips, paint dusts, surfaces, and other substances contaminated with lead by at least one application of an aqueous suspension of tricalcium phosphate, surfactant, thixotrope, and a chloride source.

Motorized wheels in a wheelchair or other light vehicle are each mounted on an axle for limited rotation relative to a secondary connection to the frame of the vehicle which incorporates a sensor providing feedback which controls the motor according to torque sensed through the secondary connection. The motor and associated gearing and control circuitry are housed within a wheel hub of which a drum supporting a wheel rim is supported at its inner surface on multiple bearings spaced around its periphery.

The invention relates inter alia to a method of treating tumorous disease in a human patient by administering to the patient a human immunoglobulin specifically binding to the human EpCAM antigen, the immunoglobulin exhibiting a serum half-life of at least 15 days, the method comprising the step of administering the immunoglobulin no more frequently than once every week, preferably no more frequently than once every two weeks.

A pharmaceutical combination comprising (a) an ALK inhibitor, or a pharmaceutically acceptable salt thereof, and (b) at least one HDMA-2 / p53 receptor inhibitor or a pharmaceutically acceptable salt, or at least one BRaf inhibitor or a pharmaceutically acceptable salt, and optionally a pharmaceutically acceptable carrier, for simultaneous, separate or sequential administration; the uses of such combination in the treatment of cancer; and methods of treating a subject suffering from a proliferative disease comprising administering a therapeutically effective amount of such combination.

The invention relates inter alia to a method of treating tumorous disease in a human patient by administering to the patient a human immunoglobulin specifically binding to the human EpCAM antigen, the immunoglobulin exhibiting a serum half-life of at least 15 days, the method comprising the step of administering the immunoglobulin no more frequently than once every week, preferably no more frequently than once every two weeks.

A flowable, injectable composite that comprises mineralized allograft bone; and at least one degradable polyurethane that has a quasi-prepolymer and a resin mix, the resin mix having a polyester polyol and a catalyst; wherein the composite has a compression strength of greater than about 10 MPa and a modulus of greater than about 1 GPa.

A brake monitoring system is described for use on aircraft having carbon brakes. The system displays the number of times the brakes have been applied in a preselected counting interval such as during each takeoff and landing cycle. By raising the pilot's awareness of the number of times the brakes have been applied, a more efficient brake use is encouraged in view of the knowledge that carbon brake wear is substantially a function of the number of applications rather than the total energy that is converted thereby. Additionally, the monitoring system provides an indication of the temperature of the brakes which encourages the pilot to maintain a minimum temperature therein beyond which wear is reduced.

A brake monitoring system is described for use on aircraft having carbon brakes. The system displays the number of times the brakes have been applied in a preselected counting interval such as during each takeoff and landing cycle. By raising the pilot's awareness of the number of times the brakes have been applied, a more efficient brake use is encouraged in view of the knowledge that carbon brake wear is substantially a function of the number of applications rather than the total energy that is converted thereby. Additionally, the monitoring system provides an indication of the temperature of the brakes which encourages the pilot to maintain a minimum temperature therein beyond which wear is reduced.

The invention relates to a method for producing tubular bags made from plastic film or from composite film having a plastic layer on the bag content side, having a self-cutting plastic closure attached to the tubular bag, consisting of a spout part having a fastening flange, a cutting body, which is movably guided in the spout part, and a screw cover having means for activating the cutting body. The film material (5) is supplied from a supply roll to a bag manufacturing machine and the plastic closure is sealed onto the film material in a spout region of a tubular bag. According to the invention, the film material (5) is thinned on the inside of the bag in a ring-shaped region, which is intended for cutting by the cutting body, by means of a thermal embossing process. The plastic closure is then positioned and sealed onto the film material such that the cutting organ embedded in the spout part can become effective in the thinned, ring-shaped region upon use thereof.

Methods and systems for temporarily coating intra-oral devices (e.g., orthodontic brackets and / or wires) so as to reduce discomfort to soft tissues within a patient's mouth. One embodiment of such a system includes at least one orthodontic bracket or orthodontic arch wire and a two-part polymerizable temporary coating composition for use in coating selected surfaces of the brackets and / or wires. One silicone polymerizable two-part composition includes a vinyl siloxane component, a cross-linking component, and a catalyst activator initially divided between the two parts so that at least one of the components is kept separate from at least one other component (i.e., all three components are not initially commingled). Upon mixing of the first and second parts, the composition begins to polymerize.

The invention relates to a method for producing a sensor (1), wherein a carrier chip (2) is produced. Said chip is provided with a sensor structure (3) comprising an active sensor surface (4). A material (9) capable of flowing is applied onto carrier chips (2) in such a way that the sensor structure (3) has a thinner layer thickness on said active sensor surface (4) than on the area of the carrier chip (2) which borders on the active sensor surface (4). The material (9) which is capable of flowing is hardened thereafter. The hardened material (9) is subsequently removed by chemical means from the surface which faces said carrier chip (2) until the active sensor surface of the sensor structure is layed bare.

An air conditioning case includes a first partition wall that receives a condensed water generated by an evaporator, and the first partition wall is disposed above an overlapped portion of a heater core and between the evaporator and the heater core. Therefore, the first partition wall can prevent the condensed water dropped from the evaporator from being applied directly to the heater core. As a result, in a structure in which at least a portion of the heater core overlaps with the evaporator from below, the condensed water of the evaporator is less likely to be applied to the heater core.

The present invention relates to a method and a device for an error correction of transmitted data. For this purpose, the transmitted data are encoded in a block code, wherein the block code comprises a number of data bits and an additional number of redundant bits. Herein the block code is described by a parity-check matrix H, wherein columns of the parity-check matrix Hare inherently related to the data bits of the block code. The method according to the present invention comprises the following steps: (a) diagonalizing the parity-check matrix H, with respect to at least one column of the parity-check matrix H, into a diagonalized parity-check matrix H′, wherein the diagonalized parity-check matrix H′ is related to the block code and to the at least one column; (b) determining at least one error position (130) in the block code by using the diagonalized parity-check matrix H′ and a syndrome vector, wherein the syndrome vector is related to the data bits in the block code; (c) performing the error correction of the transmitted data at the at least one error position (130) in the block code. The present method and device allow providing communication channels with increased reliability and enhanced correction capability at reduced complexity, and is generally applicable to all known block codes, such as turbo, LDPC, BCH, or Reed-Solomon codes.

A low profile spa jet having a structure allowing for the use of a jet housing for both threaded / nut and grommet installation, wherein the jet protrudes into the spa tub less than 0.5″. The low profile spa jet also can have a jet face / flange that is interchangeable between threaded and grommet jet bodies without changing the relationship to the spa wall, wherein the jet protrudes the same amount in the installed state for both styles of jet body. The low profile spa jet also can have a jet face / flange that is removable and / or interchangeable before and after the jet body and jet internal are installed in the spa.

Novel compositions for treating wounds and promoting the healing thereof are described, including composition containing novel combinations of a carrier and recombinant platelet derived growth factor having fewer isoforms and enhanced biostability. Methods of treating wounds with novel therapeutic composition using dosing procedures leading to effective results with a minimal number of treatment applications are also described.

The present invention provides an exchangeable-battery photocuring device, comprising a supporting frame, having a plurality of walls, wherein the plurality of walls constitutes a chamber having at least one opening; a UV LED module, disposed on the supporting frame; a outer housing, having an external opening corresponding to the opening of the supporting frame; a control module; an exchangeable battery module, disposed on the supporting frame, wherein the exchangeable battery module comprises a battery holder and a battery, and the exchangeable battery module is electrically connected to the control module, and a handle. The present invention applying an exchangeable battery module achieves that the photocuring device is used without being constrained by location and space. Furthermore, the present invention also provides an exchangeable-battery photocuring device with a slidable lid and a portable battery photocuring device with a slidable lid.

The present invention generally relates to the use of synergistic amounts of Bacillus thuringiensis subsp. aizawai, Bacillus thuringiensis subsp. kurstaki and chlorantraniliprole for the control of diamondback moth, beet armyworm, sugarcane borer, soybean looper, corn earworm, cabbage looper and southwestern corn borer, wherein the ratio of Bacillus thuringiensis subsp. kurstaki to Bacillus thuringiensis subsp. aizawai is from about 1:0.47 to about 1:0.92, and the ratio of the total amount of Bacillus thuringiensis to chlorantraniliprole is from about 1:0.0001 to about 1:20.