35results about How to "Efficient localization" patented technology

A directional brain stimulation lead assembly provides a lead body and an insulating member defining one or more windows that selectively expose portions of electrodes carried by the lead body to produce a directional stimulation current field. The lead assembly can achieve more effective localization of electrical stimulation to very small brain targets, and thereby reduce the incidence of material side effects caused by collateral stimulation of brain tissue adjoining a desired brain target. In addition, the directional lead can sense brain activity on a more localized basis.

Electrocardiogram (ECG) recorded signals are processed by a computer-implemented method to substantially remove extraneous signals to produce intermediary signals, and to separate the intermediary signals using a non-orthogonal transformation method such as independent component analysis to produce independent components of signals. The separated signals are displayed to help physicians to analyze medical conditions and to identify locations of abnormal heart conditions.

Antibodies that specifically bind to toxins of C. difficile, antigen binding portions thereof, and methods of making and using the antibodies and antigen binding portions thereof are provided herein.

The present invention features a solar-to-electric energy conversion device based on a light absorbing electrode coupled to a one-dimensional nanoparticle based photonic crystal. The function of the latter is to localize the incident light within the electrode thus enhancing the optical absorption and the power conversion efficiency of the so called dye-sensitized and organic (polymer based or hybrids) cell. The photonic crystal comprises alternating layers possessing different index of refraction and can be easily integrated into the cell.

The present invention concerns peptide sequences that specifically recognize cells of human hepatic metastases. The invention comprises also the use of nucleic acids coding for such peptides, as well as conjugates and formulations of such peptides for diagnostic and therapeutic purposes.

The present invention concerns an antibody specific for human ALK (Anaplastic Lymphoma Kinase), in particular a scFv, a nucleic acid sequence encoding it, its production and its use as a pharmaceutical or for diagnostic purposes. Said antibody is suitable for the local treatment of tumors, in particular glioblastoma.

The invention discloses a secure distributed database interaction method suitable for a mobile positioning system. The secure distributed database interaction method comprises seven modules, wherein arest data transceiving and attribution region division module is used for receiving client data and determining an attribution through an improved trie tree algorithm; a read-write separation local database module designs a statistical-based read-write separation algorithm to carry out read-write separation and temporary table establishment; a local key agreement module is used for designing a key agreement protocol on the basis of the pre-shared key and generating a session key; an attribution secret key negotiation module interacts with the local secret key negotiation module to generate asession secret key each time; a local data encryption and decryption and integrity protection module is responsible for encryption and decryption of local interaction data through an improved SM4 encryption algorithm; an attribution data encryption and decryption and integrity protection module is used for realizing encryption and decryption of attribution interaction data by designing and improving an SM4 encryption algorithm; and a read-write separation attribution database module is used for realizing read-write of the attribution database based on a statistical read-write separation algorithm.

The present disclosure provides a two-dimensional material detector with an asymmetrically integrated optical microstrip antenna, structurally including a metal reflecting surface, a dielectric spacer layer, a two-dimensional active material layer, a top source electrode, and a drain electrode integrated with a metal strip array. Self-driven photoresponse of a metal/two-dimensional material/metal structure is induced by a Schottky junction formed due to contact between the two-dimensional material and the metal. The asymmetrically integrated optical microstrip antennas break the symmetry between the two contact/two-dimensional material junctions. Light absorption in the contact/two-dimensional material junction integrated with optical patch antennas is significantly enhanced by efficient light in-coupling and intensified light localization; meanwhile, the extended boundary of the contact/two-dimensional material junction enlarges the photocurrent collection area. The light absorption in the other contact/two-dimensional material junction is significantly inhibited by a metal bottom surface which is very close to the two-dimensional material.

An improved magnetically-confined anode plasma pulsed ion beam source. Beam rotation effects and power efficiency are improved by a magnetic design which places the separatrix between the fast field flux structure and the slow field structure near the anode of the ion beam source, by a gas port design which localizes the gas delivery into the gap between the fast coil and the anode, by a pre-ionizer ringing circuit connected to the fast coil, and by a bias field means which optimally adjusts the plasma formation position in the ion beam source.

A method, a system and a computer readable medium for automatic segmentation of a 3D medical image, the 3D medical image comprising an object to be segmented, the method characterized by comprising: carrying out, by using a machine learning model, in at least two of a first, a second and a third orthogonal orientation, 2D segmentations for the object in slices of the 3D medical image to derive 2D segmentation data; determining a location of a bounding box (10) within the 3D medical image based on the 2D segmentation data, the bounding box (10) having predetermined dimensions; and carrying out a 3D segmentation for the object in the part of the 3D medical image corresponding to the bounding box (10).

An image forming apparatus includes an image bearing member, a developing device, and an intermediate transfer member. The developing device includes a toner container containing a toner. The intermediate transfer member is charged to 3.0 nC/g or less in terms of absolute value at the surface thereof. The toner particles include a surface layer, and the brightness histogram of the toner particles has two local maximums P1 and P2 and a local minimum between P1 and P2. P2 is derived from the organosilicon polymer. P1 lies in a brightness range of 20 to 70, and P2 lies in a brightness range of 130 to 230. The number of pixels of P1 and the number of pixels of P2 are each 0.50% or more relative to the total number of pixels. The total numbers of pixels A1, AV, and A2 each in a specific brightness range satisfy specific relationships.

A biocompatible, resorbable collagen membrane containment member for a bone regenerative material, and a method of using such a containment member to regenerate a bone defect by surgically accessing the bone defect; disposing the containment member adjacent the bone defect, and thereafter injecting a bone regenerative material into the containment member.