The invention provides a medical cold compress plaster. The medical cold compress plaster is composed of a support layer, a gel layer and an isolating layer, and has the special shape according with the physiological curve of the applied part. An
oil phase and a water phase forming the hydrophilic gel layer respectively comprise the following components in percentage by weight: the
oil phase: 20-35% of a dispersing agent, 5-7% of
macromolecule resin, 0.05-0.15% of
dihydroxyaluminium aminoacetate, 0.01-0.15% of
ethylene diamine tetraacetic acid, 0.15% of absolute ethyl
alcohol, 0.04-0.1% of
menthol, 0.1-1% of
vitamin E, and 0.05-0.1% of
triclosan; the water phase: 0.2-0.8% of
tartaric acid, 1.2-2% of carbomer, 0.5-1% of
sodium carboxymethylcellulose, 0.01-0.1% of
vitamin C, the balance of medical
purified water, and the total weight percentage is 100%. A preparation process comprises the following steps: dispersing all the components of the
oil phase into the dispersing agent, and uniformly stirring the components; dissolving all the components of the water phase into water, and uniformly stirring the components; mixing the water phase and the oil phase, uniformly stirring the water phase and the oil phase in a
vacuum mixing pot, thus obtaining the hydrophilic gel substrate of the medical cold compress plaster,
coating the support layer with the hydrophilic gel substrate, meanwhile covering with the isolating layer, and carrying out
cutting, solidifying and packaging to obtain the needed medical cold compress plaster product.