The invention relates to an OLED (Organic Light Emitting Diode) pixel compensation circuit and an OLED pixel compensation method, seven thin film transistors, one compensation capacitor and one organic light emitting diode are adopted to form a 7T1C framework, and the driving time sequence of pixels is sequentially divided into four stages of resetting, compensation, data storage and light emitting. As the seventh thin film transistor is in a closed state in the reset, compensation and data storage stages, the organic light emitting diode does not emit light, and the seventh thin film transistor is in an open state in the light emitting stage, the current flowing through the organic light emitting diode is irrelevant to the threshold voltage and the driving voltage of the organic light emitting diode. By adopting the technical scheme, not only can threshold voltage drift of the driving thin film transistor be effectively compensated, but also brightness change caused by electrical deterioration of the organic light-emitting diode can be compensated, and the display quality of the organic light-emitting diode is improved.