The invention discloses a high quality and yield culture technology of pinellia ternate, which comprises the following steps: land selection and preparation, seeds preparation, sowing, field management, harvesting and prevention and cure of plant diseases and insect pests. The technology of the invention is characterized in that: the loosening, fertile, neutral or subacid soil with convenient irrigation and relatively light texture, such as red oil sandy soil, hilly oil sandy soil, tide sandy mud, purple sandy mud, hilly sandy mud or ash pack soil, and the like, is chosen; before sowing, plough is carried out as per depth of 0.2m, and the suitable time for sowing is from February 20 to March 10, bottom fertilizer application is carried out according to the dosage of 180-220kg per mu, and soil is covered; before sowing, the medium-sized or small healthy stems which have the diameter of 0.5-1.5cm, regular shape and no plant diseases and insect pests are selected as the seeds (seed stems), and the stems are soaked into the 500-1000 times of liquid of 50% carbendazim for 10-20 minutes. The effect of the method is to improve the yield of pinellia ternate by 18%-22%, improve the water-soluble extracts by 10%-15%, increase the content of total alkaloid of by 18%-24%, and increase the benefit by 15%-20%.