The present invention relates to an improved
controlled release system that can encapsulate different flavors, sensory markers, and active ingredients, or combinations of flavors, sensory markers and various active ingredients and release multiple active ingredients in a consecutive manner, one after the other. The
controlled delivery system of the present invention is substantially free-flowing
powder formed of
solid hydrophobic nanospheres that are encapsulated in a
moisture sensitive microspheres. The flavors, and active ingredients encapsulated in the hydrophobic nanospheres, in the water sensitive
microsphere, or in both the nano and the
microsphere. The flavors and active ingredients encapsulated in the nanospheres can be the same or different from those encapsulated in the microspheres. The encapsulation of different flavors or active agents in the various components of the
system, such as nanospheres and microspheres, provides
flavor transition (change in
flavor character) during the use of the products. The
controlled release system of the present invention enhances the stability and
bioavailability of wide range of flavors, sensory markers, and other active ingredients, prolong their
residence time in the
oral cavity, control their release characteristics, and prolong the
sensation of flavors and other sensory markers in the mouth to provide
long lasting organoleptic perception or
long lasting mouthfeel. The invention further relates oral care,
food products, and beverages comprising the
controlled release system of the present invention.