The invention belongs to the technical field of special alloy refinement and in particular relates to a slag system for ingot stripping and electroslag remelting of a nickel-based alloy plate blank. The slag system comprises the following components in percentage by weight: 60%-65% of CaF2, 15%-20% of Al2O3, 13%-15% of CaO and 6%-10% of SiO2; the melting point of the slag system is 1,100-1,150 DEG C, the viscosity at 1600 DEG C is 0.04-0.07Pa.s, and the slag resistance at 1600 DEG C is 0.27-0.3 ohm.cm. The nickel-based alloy plate blank subjected to ingot stripping and electroslag remelting, produced by adopting the slag system is good in surface quality and free of remarkable defects such as double skin and slag inclusions; the interior quality of the plate blank is detected according to GB/T1979-2001 standards, the defects of looseness, segregation, white bands, subsurface bubbles, residual shrinkage cavities, skull patch, fish eyes, axial intercrystalline cracks, interior bubbles, non-metallic inclusions, slag inclusions, dissimilar metal inclusions and the like are not discovered, and the interior quality of steel ingot is good.