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83 results about "Surgical excision" patented technology
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Surgical excision is the removal of tissue using a sharp knife (scalpel) or other cutting instrument. Olbright S. Biopsy techniques and basic excisions.
Intussusception and anastomosis apparatus
Apparatus for intratubular intussusception and anastomosis of a hollow organ portion including a cylindrical enclosure, coaxial intratubular intussusception device, for intussusception and clamping means. The apparatus also includes an intratubular anastomosis apparatus for joining organ portions after intussusception thereof with an anastomosis ring and crimping support element. The ring is formed of a shape memory alloy wire, for crimping adjacent organ portions against the crimping support element so as to cause anastomosis therebetween. The ring assumes a plastic or malleable state, at a lower temperature and an elastic state at a higher temperature. The apparatus further includes the crimping support element for intratubular insertion so as to provide a support for crimping the organ portions against the support element. The apparatus additionally includes a surgical excising means, for excising an intussuscepted organ portion, after crimping adjacent intussuscepted organ walls against the crimping support element with the anastomosis ring.
Owner:NITI SURGICAL SOLUTIONS
Hybrid imaging method to monitor medical device delivery and patient support for use in the method
ActiveUS20050080333A1Easy procedureConvenient treatmentSurgical needlesStretcherLiver and kidneySurgical removal
This invention discloses a method and apparatus to deliver medical devices to targeted locations within human tissues using imaging data. The method enables the target location to be obtained from one imaging system, followed by the use of a second imaging system to verify the final position of the device. In particular, the invention discloses a method based on the initial identification of tissue targets using MR imaging, followed by the use of ultrasound imaging to verify and monitor accurate needle positioning. The invention can be used for acquiring biopsy samples to determine the grade and stage of cancer in various tissues including the brain, breast, abdomen, spine, liver, and kidney. The method is also useful for delivery of markers to a specific site to facilitate surgical removal of diseased tissue, or for the targeted delivery of applicators that destroy diseased tissues in-situ.
Owner:INVIVO CORP
Method of using cryotreatment to treat brain tissue
A method is disclosed for treating brain tissue with cryotreatment. A surgical tool, such as a catheter is disposed proximate to a target region of brain tissue. The tool or catheter provided includes a cryotreatment element. The cryotreatment element may be a cryochamber for enclosing the flow of a fluid refrigerant therein. The cryotreatment element is disposed at the situs of brain tissue to be treated, either through endovascular insertion, or via an opening in the cranium. A refrigerant flow within the cryochamber creates endothermic cooling with respect to the surrounding brain tissue, inducing hypothermia and forming iceballs proximate said tissue. The cooling may be reversible and non-permanent, or may be permanent leading to cell death, necrosis, apoptosis and / or surgical excision or ablation of tissue. Mapping using conventional techniques may be used to measure and assess brain function before and after cryotreatment, and cryotreatment itself may be integrally and progressively used to map brain function and treat tissue.
Owner:MEDTRONIC CRYOCATH LP
Surgical device for minimally invasive spinal fusion and surgical system comprising the same
A surgical device is disclosed which may advantageously perform the functions of both a retractor and a distractor. The device has two retractor blades facing each other and held in a common frame, the retractor blades are insertable into a surgical incision in a patient and moveable away from each other along a main axis (x) so as to widen the surgical incision; and a connecting pin attached at a distal end of each retractor blade. Each connecting pin is attachable to a pedicle screw anchored to respective vertebrae of the patient, so that moving away the two retractor blades along the main axis (x) determines a distraction of the vertebrae.
Owner:MEDACTA INT SA
Method and device for epicardial ablation
A method is disclosed for treating heart and vascular tissue with cryotreatment. A medical instrument, such as a catheter is positioned to contact a target region of cardiac tissue such as the epicardial tissue. The instrument or catheter provided includes a cryotreatment element that has thermally-transmissive properties. The cryotreatment element may be a cryochamber for enclosing the flow of a fluid refrigerant therein. The cryotreatment element is disposed at the situs of heart or vascular tissue to be treated, usually by piercing the epicardium sac via an opening in the patient's body. A refrigerant flow within the cryochamber creates endothermic cooling with respect to the targeted heart or vascular tissue, inducing hypothermia and forming iceballs proximate the tissue. The cooling may be reversible and non-permanent, or may be permanent leading to cell death, necrosis, apoptosis and / or surgical excision or ablation of tissue.
Owner:MEDTRONIC CRYOCATH LP
Applications of HIFU and chemotherapy
InactiveUS20070088345A1Promote absorptionUltrasonic/sonic/infrasonic diagnosticsSonopheresisAbnormal tissue growthMilia
A method, using high intensity ultrasound, which may also be combined with a chemotherapy agent, that can result the direct destruction of tumor cells and in the reduction or elimination of local reoccurrence of cancer after removal of cancerous tissue, such as a surgical breast lumpectomy or surgical excision of a brain tumor. The method comprises either (1) the treatment of the tumor directly with High Intensity Focused Ultrasound, or (2) the treatment of the margins of the tissue surrounding the surgical cavity or void with ablative continuous wave high intensity ultrasound and a combination of a locally delivered chemotherapy agent and high intensity ultrasound, termed sonoporation. The present invention permits both the direct destruction (ablation) of tumor tissue as well as the destruction of tissue around the surgical margin and may include the enhanced local cellular uptake of locally injected chemotherapeutic drugs, all of which can be accomplished by a therapeutic ultrasound device used during surgery.
Owner:UST INC
Method and device for epicardial ablation
A method is disclosed for treating heart and vascular tissue with cryotreatment. A medical instrument, such as a catheter is positioned to contact a target region of cardiac tissue such as the epicardial tissue. The instrument or catheter provided includes a cryotreatment element that has thermally-transmissive properties. The cryotreatment element may be a cryochamber for enclosing the flow of a fluid refrigerant therein. The cryotreatment element is disposed at the situs of heart or vascular tissue to be treated, usually by piercing the epicardium sac via an opening in the patient's body. A refrigerant flow within the cryochamber creates endothermic cooling with respect to the targeted heart or vascular tissue, inducing hypothermia and forming iceballs proximate the tissue. The cooling may be reversible and non-permanent, or may be permanent leading to cell death, necrosis, apoptosis and / or surgical excision or ablation of tissue.
Owner:MEDTRONIC CRYOCATH LP
Contrast enhancing solution for use in confocal microscopy
InactiveUS7128894B1Improve featuresIncrease contrastIn-vivo testing preparationsRadiologyContrast enhancement
A method of optically detecting a tumor during surgery. The method includes imaging at least one test point defined on the tumor using a first optical imaging system to provide a first tumor image. The method further includes excising a first predetermined layer of the tumor for forming an in-vivo defect area. A predetermined contrast enhancing solution is disposed on the in-vivo defect area, which is adapted to interact with at least one cell anomaly, such as basal cell carcinoma, located on the in-vivo defect area for optically enhancing the cell anomaly. Thereafter the defect area can be optically imaged to provide a clear and bright representation of the cell anomaly to aid a surgeon while surgically removing the cell anomaly.
Owner:THE GENERAL HOSPITAL CORP
Mandibular bone transport reconstruction plate
This device can be used to create new bone to fill a gap in the mandible after surgical excision. It uses a bone reconstruction plate as a distraction device. The reconstruction plate fixes the bone stumps on both sides of the bone gap. In the middle segment of the plate overlying the bone gap, the transport bone disc is carried on a transport unit that moves along a rail on the outer surface of the reconstruction plate.
Owner:CRANIOTECH ACR DEVICES
Mandibular bone transport reconstruction plate
This device can be used to create new bone to fill a gap in the mandible after surgical excision. It uses a bone reconstruction plate as a distraction device. The reconstruction plate fixes the bone stumps on both sides of the bone gap. In the middle segment of the plate overlying the bone gap, the transport bone disc is carried on a transport unit that moves along a rail on the outer surface of the reconstruction plate.
Owner:CRANIOTECH ACR DEVICES
Conversion of calcite powders into macro- and microporous calcium phosphate scaffolds for medical applications
Disclosed is a method for forming carbonated calcium hydroxyapatite. The disclosed method can be used for forming bone cements or optionally cast, cured scaffolds such as may be used in many medical applications, including as implants for bone damage caused by, for instance, trauma, disease, or surgical excision due to disease. The cured materials include an interconnected network including both microporosity and macroporosity. The disclosed materials can be very similar in both chemical and physical make-up to natural bone mineral. The invention is also directed to systems that can be used for conveniently carrying out the disclosed methods.
Owner:CLEMSON UNIVERSITY
Probes for electrical current therapy of tissue, and methods of using same
Disclosed herein are probes for use in delivering electrical current therapy to a target tissue. In specifically exemplified embodiments, the probes comprise a base comprised of a degradable material so as to prevent the potentially dangerous reuse of the probes. Also disclosed is a surgical tool for use in rectal examination and surgical removal of hemorrhoid tissue. The tool includes an anoscope having a somewhat conical shape wherein the proximal end is larger in diameter than the distal end. The anoscope has a first slot near the proximal end and a second slot near the distal end. An obturator is included that also has a somewhat conical shape. The obturator is smaller in diameter than the anoscope so that it will easily fit within the anoscope. A cylindrical shaped light cover is included as well, which is adapted to engage the first slot of the anoscope. The light cover further includes a receptacle and a lens in its distal end which receives a light.
Owner:MEDFINITI IP BV
Application of digitization technology to oral approach mandibular condylar lesion surgical excision
InactiveCN104720877APostoperative cosmetic effectMinimally invasiveSpecial data processing applicationsSurgical sawsDigital imagingNavigation system
The invention relates to application of a digitization technology to oral approach mandibular condylar lesion surgical excision. The application comprises the following steps: planting five self-tapping titanium screws into a mandible of a patient to be used as registration mark points of a navigation system in a surgery; photographing maxillofacial region CT (Computed Tomography) scanning and storing in a DICOM (Digital Imaging and Communications in Medicine) format; establishing a patient lesion three-dimension pattern; designing an osteotomy face and an osteotomy range according to a lesion boundary; introducing navigation software in an STL (Standard Template Library) format to reestablish a three-dimensional geometrical model; mounting a navigation reference frame, and registering by using a navigation positioning probe and the mark points; setting an incision and dissecting and separating a joint capsule under an endoscope view to expose a condylar process; searching an osteotomy face position by using the positioning probe and calibrating a coordinate of a bone saw; adjusting the bone saw to the position of the osteotomy face and the cutting angle; and under the guidance of the incision stretched endoscope probe and a navigation positioning image, carrying out condylar osteotomy by holding the bone saw via a surgery doctor. By the aid of the application, the surgery doctor can accurately cut off condylar tumors according to preoperative plans, so the ideals of minimally invasive surgery and accurate surgery are uniformed.
Owner:王旭东 +1
Fluorescence navigation system used in tumor surgery
InactiveCN101770141AExcision completelyReduce mortalityPhotographyAbnormal tissue growthLymphatic Spread
The present invention relates to a fluorescence navigation system used in tumor surgery, which belongs to clinical medicine surgery. The present invention solves problems existing in the surgical excision operation process of tumors that tumor boundaries are difficult to identify, remnant tumor tissue is difficult to recognize, and tumor metastasis lymph glands are difficult to track. The fluorescence navigation system used in tumor surgery is characterized in that the system comprises a biofluorescence excitation light source, a light guide system, a specificity targeted marking fluorescent material, a video camera and an image display and processing device connected with the video camera. The present invention provides fluorescence navigation concept for tumor surgery based on the prior art. When physicians identify tumor boundaries, recognize remnant tumor tissue, and track tumor metastasis lymph glands with a fluorescence observing mirror or a camera display system, tumor tissue is thoroughly excited, operation therapeutic effect is effectively improved, and the death rate of tumor patients is reduced. The present invention makes a breakthrough in tumor surgery.
Owner:SHANXI MEDICAL UNIV
Tissue positioning systems and methods for use with radiation therapy
InactiveUS20050085681A1Protect sensitive tissueLimited amountDiagnosticsSurgeryBrachytherapy deviceProximate
A brachytherapy device including a spacing member is disclosed herein. The spacing member is useful in that the instrument is effective to limit the amount of radiation that comes into contact with the sensitive tissue, and thereby protect sensitive tissue from overheating or hotspots, and / or protect against radiation exposure outside of the patient's body which may affect healthcare providers or others who might come close to the patient. In particular, the spacing apparatus is effective to control the proximity of a brachytherapy device to the outer surface of the sensitive tissue proximate to a surgical excision site.
Owner:CYTYC CORP
Personalized prosthesis and making method and using method thereof
InactiveCN106175998AImprove surgical precisionImprove surgical safetyAdditive manufacturing apparatusSpinal implantsPersonalizationProsthesis
The invention discloses a personalized prosthesis and a making method and using method thereof. The making method comprises the steps of image acquisition, three-dimensional digital modeling, resin model establishment, computerized surgery simulation, model revalidation, internal fixation scheme making, prosthesis size formulation, personalized prosthesis parameter determination, prosthesis 3D printing and prosthesis cooling and cleaning. The personalized prosthesis obtained through 3D printing is especially suitable for spine, prosthesis design and simulation of reestablishment of a spine structure after excision can be conducted with a computer before operation, specific schemes can be made according to requirements of patients, and surgery precision and safety are improved.
Owner:BEIJING ZHONGNUO HENGKANG BIOTECH
Method for treating cervical cancer
InactiveUS7582287B2Heavy metal active ingredientsBiocideHuman papilloma virus infectionWhite blood cell
Use of Interleukin-20 for treating cervical cancer or cells infected with human papilloma virus. IL-20 can be administered alone or in conjunction with radiation or chemotherapeutic agents or surgical excision of the involved cells or lesions.
Owner:ZYMOGENETICS INC
Tumor grid organ model 3D printing method
The invention relates to a tumor grid organ model 3D printing method. The method particularly comprises the following steps: a cross section and a sagittal section when a human body is in a supine position are used for building crossed multiple grids on the surface of an organ, while the 3D grids are built, 3D modeling software specially adopted for original data for medical imaging (CT or MRI) picks out an organ or a tumor or a blood vessel in need of 3D printing, and building of 3D data is carried out. 3D data for the organ or the tumor or the blood vessel are built at the same time, and organ surface 3D grid data are built. The 3D data are inputted to a 3D printer for 3D model printing. According to the printed model of the invention, the tumor can be intuitively observed via a hollow organ shell and the distance between the tumor and the organ surface can be measured, a guide is provided for surgical resection, and a spatial distance between the tumor or the blood vessel inside the organ and an anatomical site on the organ surface can be directly read from the model.
Owner:王峻峰
Mandibular Bone Transport Reconstruction Plate
Owner:CRANIOTECH ACR DEVICES
Applications of hifu and chemotherapy
InactiveCN1947662AIncrease intakeUltrasonic/sonic/infrasonic diagnosticsSonopheresisSurgical operationHigh-intensity focused ultrasound
Owner:UST INC
Simulated dissectible tissue
A simulated tissue structure for surgical training is provided. The simulated tissue structure includes a first layer made of silicone and a second layer made of silicone interconnected by a third layer made of polyester fiber that is embedded in part in the first layer and in part in the second layer to create a mechanical linkage between the first layer and the second layer. Part of the third layer that is adjacent to the first layer and part of the third layer that is adjacent to the second layer includes fiber strands coated in silicone. An inclusion that mimics an anatomical structure is located between the first layer and the second layer. The third layer of polyester fibers provides a realistic dissection plane for the practice of the surgical excision of the inclusion.
Owner:APPL MEDICAL RESOURCES CORP
Non-invasive approach for assessing tumors in living animals
InactiveUS6926890B2Solve the lack of heightBiocideGenetic material ingredientsAbnormal tissue growthHalf-life
A means for following the growth of experimental neoplasms involves administering recombinant tumor cells containing an expression construct encoding a secretable marker to an experimental animal and measuring secreted marker in the urine of animals bearing tumors formed by such recombinant tumor cells. Urinary marker levels are quantitatively related to tumor loads. Urinary marker can be detected before tumors are grossly visible or clinically apparent. Marker levels decrease following surgical excision or chemotherapeutic treatment, with an estimated half-life of 11 hours. This approach is applicable to the study of many experimental tumor systems.
Owner:VOGELSTEIN BERT +2
Soft tissue lesion excision guide
InactiveUS20150057531A1Surgical needlesVaccination/ovulation diagnosticsSoft tissue lesionSoft tissue injury
The present invention is a device, system and method for surgical soft tissue lesion excision. The device is designed to be placed into a soft tissue lesion preferably under radiologic guidance and deployed. Once deployed, the shape memory wires of the soft tissue encompassing element form a wire cage surrounding the lesion which acts as an excision guide, encompassing and protecting the lesion during surgical excision of the lesion.
Owner:EXCISURE LLC
Tissue positioning systems and methods for use with radiation therapy
InactiveUS7494456B2Protect sensitive tissueLimited amountDiagnosticsSurgeryBrachytherapy deviceProximate
A brachytherapy device including a spacing member is disclosed herein. The spacing member is useful in that the instrument is effective to limit the amount of radiation that comes into contact with the sensitive tissue, and thereby protect sensitive tissue from overheating or hotspots, and / or protect against radiation exposure outside of the patient's body which may affect healthcare providers or others who might come close to the patient. In particular, the spacing apparatus is effective to control the proximity of a brachytherapy device to the outer surface of the sensitive tissue proximate to a surgical excision site.
Owner:CYTYC CORP
Oral squamous cell carcinoma organoid culture medium and culture method
PendingCN113278588AThe proportion of pollution is reducedPromote growthCulture processEpidermal cells/skin cellsSquamous CarcinomasBiology
The invention discloses a culture method of oral squamous cell carcinoma organoid. The culture method comprises the following steps: S1, preparing a dissociation enzyme; S2, preparing a culture medium, wherein the culture medium is composed of a basal culture medium DMEM / F12, an R-spondin1 conditional culture medium, a Wnt3A conditional culture medium, sterile water and functional components; S3, obtaining a sample through clinical operation, namely obtaining a tumor specimen through material taking or surgical resection, cutting tissue, washing the tissue with sterile normal saline for three times, soaking the tissue in a DMEM medium for 1 hour and continuing to dissociate; S4, tissue pretreatment, namely placing the sample obtained in the step S3 in a sterile 6-well plate, and cutting up sample tissue blocks by using a disposable sterile surgical blade; S5, tissue dissociation and digestion, namely adding the dissociation enzyme prepared in the step S1, repeating the process of centrifugation-supernatant removal for three times so as to fully remove the dissociation enzyme, and mixing the cells with the sample tissue blocks before the last time of centrifugation; and S6, carrying out organoid culture.
Owner:NANJING STOMATOLOGICAL HOSPITAL
An intervertebral prosthesis
The application relates to an intervertebral prothesis. In particular, to an articulating intervertebral disc prothesis. In use, the intervertebral prosthesis is fixed to the end plates of vertebrae following the surgical excision of a degenerative or ruptured disc. The intervertebral prothesis has substantially flat bone engaging surfaces with a macro-textured surface.
Owner:WARSAW ORTHOPEDIC INC
Application of poly(cinnamic alcohol) injection used as cyst treatment medicament
InactiveCN102240264AAvoid high recurrence ratesOrganic active ingredientsDigestive systemGynecologyPERITONEOSCOPE
The invention belongs to the technical field of poly(cinnamic alcohol) injection medicament application, and in particular relates to application of a poly(cinnamic alcohol) injection used as a cyst treatment medicament. Conventional cyst treatment methods mainly comprise surgical excision, laparoscopic excision and others, with the disadvantages of long incision, multiple bleeding, severe wound, high cost and easy recurrence. In the application of the poly(cinnamic alcohol) injection used as the cyst treatment medicament provided by the invention, the medicament therapy is used to replace surgery therapy, 1% of the poly(cinnamic alcohol) injection is injected into the endothelial cells with the secretory function in the cyst wall, thus resulting in aseptic inflammation and the cyst is solidified, hardened, adhered, closed and gradually absorbed so as to disappear. According to the invention, the cyst patients can be treated without hospitalization, and the high cyst recurrence rate caused by incomplete surgical excision is avoided.
Owner:SHAANXI TIANYU PHARMA
Nasal drip oil for pediatric adenoidal hypertrophy as well as preparation method and use method thereof
InactiveCN108126036AImprove sleepingAvoid facePharmaceutical delivery mechanismRespiratory disorderNasal cavityTonsil
The invention relates to a pharmaceutical composition for treating pediatric adenoidal hypertrophy. The pharmaceutical composition comprises the following components in parts by weight: small centipeda herb, fructus gleditsiae, licorice root, orange peel, perilla, honeysuckle, sesame oil, cocklebur fruit, ligusticum wallichii, coptis root, chrysanthemum and peppermint. The pharmaceutical composition is prepared by crushing, stirring and decocting the components, and can be used for treating pediatric adenoidal hypertrophy which is treated without any special medicine except by surgical excision, even if a medicine is administered, the medicine is used for treating rhinitis or tonsils. The pharmaceutical composition provided by the invention is specially developed for adenoids, has a directeffect by dripping from nasal cavity and fills a gap in this field.
Owner:陈峰
Near-infrared second window emitted micro-molecular rear earth complex fluorescence probe and preparation method thereof
PendingCN108148012ADoes not affect coordination abilityTo achieve the effect of targeting tumorOrganic chemistryIn-vivo testing preparationsFluorescenceTumor targeting
Owner:FUDAN UNIV
Biflavone derivative fluorescent probe, preparation method thereof and application of biflavone derivative fluorescent probe in brain glioma imaging
ActiveCN111747918ARich varietyRealize highly sensitive detectionOrganic chemistryFluorescence/phosphorescencePhenyl groupPyran
The invention discloses a biflavone derivative fluorescent probe, a preparation method thereof and application of the biflavone derivative fluorescent probe in brain glioma imaging. The chemical nameof the biflavone derivative fluorescent probe is 1, 4-phenyl bis (4-oxo-4H-benzopyran-2, 3-diyl) diacrylate (PPDC), and the molecular formula of the biflavone derivative fluorescent probe is C30H22O8.The probe PPDC is obtained through two-step synthesis, shows great Stokes shift (261 nm), and can effectively overcome the defect of biological application blockage caused by fluorescence self-absorption. Fluorescence analysis research shows that the compound can be used for high-sensitivity detection of cysteine with the detection limit being 0.01 mu M; in addition, the probe can be used for effectively distinguishing interferent glutathione and homocysteine of cysteine in an organism. Accurate detection of trace cysteine in brain glial cells is helpful for early diagnosis of brain glioma. In view of the defects of current brain glioma in early detection and accurate excision, the method is expected to realize accurate surgical navigation in clinical surgical excision of the brain glioma, and has a good application prospect.
Owner:NANJING NORMAL UNIVERSITY
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