The invention relates to an establishing method for a rat central type superior mesenteric
vein thrombosis model. The model is established by establishing an acute central type superior mesenteric
vein thrombosis model, ligaturing the
trunk root of a superior mesenteric
vein at a time through a 7-0 no-damage nylon suture at the position 0.2 cm below the joint of the free superior mesenteric vein and a splenic vein, and conducting
abdomen closing. A sub-acute central type superior mesenteric
vein thrombosis model is established by placing a
metal stick with the
diameter of 1 mm and a superior mesenteric vein in parallel at the position 0.2 cm below the joint of the
trunk of the free superior mesenteric vein and the splenic vein, ligaturing the superior mesenteric vein and the
metal stick together through a 7-0 no-damage nylon suture, retreating the
metal stick after
ligation so that opened calibers of all rats can be kept basically consistent, and conducting
abdomen closing. Food and water are freely fed in the next day.
Abdomen opening is conducted again 48 hours later, the superior mesenteric vein is completely ligatured, and
abdomen closing is conducted. Food and water are freely fed in the next day after the second operation. The rat central type superior mesenteric
vein thrombosis model is suitable for superior mesenteric
vein thrombosis intestinal
pathology and
pathophysiology research.