Therapy for Constipation
a technology for constipation and bowel disorders, applied in the field of treatment of constipation, can solve the problems of constipation function, inadequacies of bulk-forming laxatives, over-the-counter bulk-forming laxatives,
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example 1
[0033]A 35-year-old female with fibromyalgia presented with chronic pain which is global pain disorder affecting much of her body. She was prescribed opiate medication in the form of MS Contin (60 mg twice a day—BID) for pain management. Since beginning the MS Contin, she suffered from severe constipation. She would often go 7 to 10 days without a bowel movement. She would suffer abdominal discomfort, bloating, and sometimes require manual disempaction due to the severity of her constipation. The patient was given Colace, Sennekot, and bowel stimulants to attempt to correct her chronic constipation related to the pain medication. It was only partially and intermittently successful. She was then given the recommended doses of orlistat (120 mg twice per day orally—BID) with food, and noticed an improvement within 24 hours. Within one week, she had noticed that she had daily bowel movements. She took this new medication for one year and had good well-formed bowel movements most days. S...
example 2
[0034]A 57-year-old female with fibromyalgia being treated with the tricyclic antidepressant amitriptylline suffers from a global pain disorder requiring pain management. She was treated with amitriptyline that is a known therapeutic agent for mild to moderate fibromyalgia. This tricyclic antidepressant is also known for causing dry mouth, blurry vision and constipation. She had tried Colace and Sennekot (senna) with minimal benefit. The patient was given the recommended dosage of cetilistat (60 mg orally once per day with food) for her chronic constipation and within 24 hours, she had had a bowel movement. She continued the cetilistat daily at one pill per day and was able to acquire regular bowel movements daily. She continued the medication for a year and continues to have good success with daily bowel movements. She reported no major side effects. The cetilistat demonstrated the ability to perform as a long-term therapy for constipation, but also for non-opiate medication relate...
example 3
[0035]A 75-year-old man living in a nursing home with mild dementia complained of painful bowel movements causing an anal fissure with bleeding in his rectum. The cause of his constipation was deemed to be due to a combination of non-opiate medications, dehydration, and a lazy bowel. The patient also complained of abdominal distention and some intermittent abdominal discomfort. A number of common prescription laxatives including Colace, senna, and bowel stimulants caused diarrhea. He had abdominal pain with conventional bowel stimulants. He was then given cetilistat (60 mg orally twice daily with food) which resulted in a bowel movement within 24 to 36 hours that was painless and soft. Over the course of two weeks, the anal fissure had healed and the bleeding had stopped. The patient had regular bowel movements daily and his abdominal bloating and abdominal pain had resolved. The cetilistat resolved the constipation in an acute case and allowed for long-term recovery from a constipa...
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