The invention relates to a formula and a preparing method of a freeze-dried
excipient preparation. The formula is new and simplified. By controlling the ratio of an
adhesive and the ratio of
active components in the freeze-dried
excipient preparation, the freeze-dried
excipient preparation can be free of a skeleton supporting agent
system and only contains the
adhesive and the
active components. The skeleton supporting agent comprises, but not limited to,
sugar,
sugar alcohol, amino acids having 2-12 carbon atoms,
inorganic salts, and the like. Based on this, an
antioxidant, a corrigent, essence, a
skin penetration enhancer, a pH modifier, and other auxiliary materials can be added into the preparation. By avoiding the use of the skeleton supporting agent, technical effects of reducing the
moisture adsorption risk, simplifying the preparing process, reducing the cost and increasing the
drug loading capacity per unit are achieved.