A method for identifying micro ribonucleic acid (
RNA) in the
blood serum of a
lung cancer patient through Solexa technology belongs to the biological
medicine technical field, in particular relating to a Solexa technology for measuring the expression of micro
RNA in the
blood serum of a
lung cancer patient as well as an application of the Solexa technology in clinic diagnosis and therapy such as early diagnosis of
lung cancer,
curative effect appraisement and
drug effect appraisement, etc. The Solexa technology comprises the following steps that: a Solexa sequencing method is used to measure the content of micro
RNA in the
blood serum of a
lung cancer testee; the appraisement of the physiological and / or
pathological status of the testee is to carry out
lung cancer diagnosis of the testee; and the physiological and / or
pathological status of the testee is tested after the testee receives a to-be-tested object. The Solexa sequencing method has the advantages of wide detection pedigree, high sensitivity, low detection cost, convenient material obtaining and easily stored samples, etc.; moreover, the method can be widely used in related operations including
lung cancer screening, etc. so as to improve the conditions of low specificity and low sensitivity caused by individual difference which is difficult to be overcome by a single marker; therefore, the method can substantially increase the clinic
detection rate of lung cancer, and is an effective way to carry out early diagnosis of lung cancer.