465 results about "Drug injection" patented technology

A device for painlessly injecting medications, and a method for providing a substantially painless injection of medication into a patient that does not require the use of an anesthetic, that does not require the medical personnel to spend a substantial amount of time performing the injection procedure, that is relatively simple and inexpensive to perform and operate, and that provides a relatively high degree of safety for both the medical personnel and for the patient. The injection needle can have an outside diameter greater than 0.20 mm and less than about 0.38 mm. The medicament can be injected painlessly through the needle and into the patient at a substantially constant volumetric flow rate of about 0.05 μL / s to about 50 μL / s.

A syringe assembly including an adapter, a sheath and filling spike for connecting to said adapter and an intravenous connector for intravenously administering medicine to a patient. The barrel may be connected to the adapter and the filling spike for filling the barrel with medicine. The medicine can then be injected into a patient through either the needleless intravenous injection system or through a retractable needle assembly.

A medical injection device is provided which includes a shield system and a syringe. The shield system includes a housing, a shield telescopically received in the housing slidably coupled to the housing and a driver that pushes the syringe stopper to cause drug injection. The driver is equipped with sensing elements that automatically detect empty syringe. A spring resiliently urges the shield from a retracted position to an extended position shielding the needle. The syringe is coupled to the housing. The shield is positioned externally to the syringe and the driver. The shield includes flexible latches to keep its position relative to the housing during storage and use. The axial movement of the driver in respect to the syringe causes an automatic release of the spring by sensors when the syringe is empty, allowing the spring to move and lock the shield in the extended position after use.

An apparatus for removal of premixed drugs or reconstitution of lyophilized drugs and for the injection of the reconstituted drug into the patient. The apparatus includes a syringe assembly and an adapter assembly that can be removably connected to a medicament container containing a premixed drug or lyophilized medicament. The syringe assembly of the apparatus includes a body portion to form a liquid chamber between the forward end of the body portion and the piston and a syringe cannula assembly. The syringe cannula assembly, which can be removably interconnected with the body portion, comprises a cannula support and a hypodermic needle sealably connected to the cannula support. The adapter assembly comprises an adapter preferably molded from a moldable plastic that includes a top wall, an adapter cannula connected to and extending from the top wall and a variety of connectors connected to the top wall for removably interconnecting the adapter with the medicament container. The adapter assembly further includes syringe connector member connected to the top wall for removably interconnecting the syringe with the adapter in a manner to uniquely position the syringe cannula within the lumen of the adapter cannula wherein it is completely shielded from external contamination and prevent print damage and injury to the user.

An incremental syringe useful for multiple injections of medications like botulinum toxin is provided. The syringe includes detents on the syringe plunger which provide a tactile feeling, a discrete audible sound or “click,” or preferably both, for every unit of medication aspirated or injected to or from an individual syringe. Hence, there is no need to look at the syringe, or bring it to the eye level, during use thereof. In some embodiments, a second set of detents is included, and in some embodiments a third set of detents is included. Syringe plungers useful for combining with a syringe body to produce such an incremental syringe are also described.

Drug injection device (400) comprising expelling means for expelling an amount of drug from a reservoir, the expelling means comprising setting means (411) allowing a user to set a dose to be expelled, and actuation means (413) for releasing the drug expelling means to expel the set dose. The actuation means comprises an actuation member adapted to be moved between an initial position, an intermediate position, and an actuated position in which the expelling means is actuated to expel the set dose. The device further comprises an electronically controlled capturing system (420) for capturing data representing the amount of drug expelled from the reservoir by the expelling means, and switch means for starting initialization of the capturing system when the actuation member is moved to its intermediate position.

A barrel adapter mountable to a syringe barrel includes a barrel tip, a biasing member, a locking mechanism, and a needle assembly. A safety syringe includes a barrel, a plunger assembly, and a barrel adapter. The needle assembly includes a needle, a needle hub, and a needle seal. The needle is configured to pass-through the needle assembly, locking mechanism, biasing member, and barrel tip such that, at one end the needle is within the barrel and at another end the needle passes through an aperture in the barrel tip. The barrel may be substantially cylindrical, having along its longitudinal axis a distal end for drug injection, a proximal end for injection control, and at least a portion of the barrel interior for drug containment. The barrel adapter provides needle retraction mechanisms to the barrel to form a safety syringe. Methods of assembling, manufacturing, and using such syringes are also provided.

An injection needle assembly is an assembly used by being attached to an injector including an injection barrel filled with medicine and a needle tube, and is provided with a sticking needle tube having a needle tip to be stuck into a skin, a needle holding portion, an engagement portion and a connection portion. The needle holding portion holds the sticking needle tube and a fit tube of the engagement portion is engaged with a needle hub of the injection barrel. The connection portion includes a luminal portion in which there are arranged a proximal end on the opposite side of the needle tip of the sticking needle tube and a needle tip (ejection port) at the needle tube of the injector, and the sticking needle tube and the needle tube communicate with each other in a liquid tight manner.

An assembly is provided which includes an infusion device coupled to a standard medication syringe. The medication syringe may be coupled to a stopcock valve having multiple ports and to which syringes, vial adapters, infusion tubing, and multiple other items may be coupled. The infusion device includes a source of power based on a resistance force such as vacuum, spring or gas power. The infusion device converts the resistance based force to usable work in the form of a force applicator. The force applicator includes a driver section on one section of a reciprocating arm and an attachment to the power source on another section of the arm. The driver is pulled outward (excursion) to increase the size of the chamber, creating a force that tends to return the driver back inward, causing incursion. The driver can be attached removably to the syringe plunger to induce the infusion process.

Drug injection device (400) comprising expelling means for expelling an amount of drug from a reservoir, the expelling means comprising setting means (411) allowing a user to set a dose to be expelled, and actuation means (413) for releasing the drug expelling means to expel the set dose. The actuation means comprises an actuation member adapted to be moved between an initial position, an intermediate position, and an actuated position in which the expelling means is actuated to expel the set dose. The device further comprises an electronically controlled capturing system (420) for capturing data representing the amount of drug expelled from the reservoir by the expelling means, and switch means for starting initialization of the capturing system when the actuation member is moved to its intermediate position.

To securely position a needle tip and a blade face of a needle tube inserted into the skin in a predetermined site of a living body, such as the upper layer of skin, an injection needle assembly includes a needle tube having a needle tip capable of puncturing a living body, a hub holding the needle tube, a stabilizer, and a guide portion. The stabilizer is formed in a tubular shape surrounding the circumference of the needle tube, and an end face is pressed against the skin, and thereby a raised portion of the skin is formed in a tube hole. The guide portion is arranged on the stabilizer, and is adapted to recognize a press-in distance y of the stabilizer to the skin.

A method for extracting hyperin comprises the following steps: a crude product of an extracting solution of a maniod eibish flower is obtained through extracting the concentrated solution of a maniod eibish flow ethanol extracting solution by normal butanol or ethyl acetate or through the column chromatography of an HPD100 or HPD600 macroscopic absorbent resin; and then hyperin with the content of between 90 and 98 percent in weight percentage is obtained through purification and recrystallization by using a solvent. Hyperin preparations comprise freeze-dried powder injection, liquid drugs injection, transfusions, dropped pills, tablets, capsules, or soft capsules prepared by using hyperin as an active component and pharmaceutical adjuvant. The hyperin is used for preparing the medicines for treating cerebral ischemia.

An apparatus includes a pen body of a drug injection pen including a dosage injection mechanism that produces a rotational motion when the drug injection pen dispenses a fluid. The apparatus also includes a button housing with at least part of a dosage measurement system disposed within the button housing. At least part of the dosage measurement system is coupled to receive the rotational motion from the dosage injection mechanism. The dosage measurement system includes one or more sensors positioned to output a signal in response to the rotational motion when the drug injection pen dispenses a fluid, and a controller coupled to the one or more sensors to receive the signal. A drug delivery control wheel of the drug injection pen is disposed between the body of the drug injection pen and the at least part of the dosage measurement system disposed in the button housing.

A delivery system for interstitial radiation therapy that uses a brachytherapy needle assembly for simultaneously dispensing an effective amount of medicine, such as anti-inflammatory agents, along with radioactive seeds. Medicine can be stored in and dispensed from a reservoir attached to a needle hub or to a stylet handle or it can be injected into the needle via a three-way fitting. Alternatively, medication can be added directly to the needle cannula. Additionally, the brachytherapy needle or the radioactive seeds and spacers can be coated with medication that would be absorbed by the body upon implantation.

The present invention relates to a device, system and a method for optimizing syringe based drug delivery profile with a treatment element and in particular, to such a device, system and method in which optimization is based on a plurality of data that directly and / or indirectly affect the optimization of the drug delivery profile. The device facilitating syringe based drug delivery, by optimizing drug delivery of the injected drug, records user's activity, and data relative to drug injections, comprising a disposable unit configured for a single use period and a rechargeable reusable unit having electronics comprising a sensor module.

The present invention provides a device (1) for monitoring the application of a drug to a patient by means of a drug pen (100), whereby the drug pen comprises a front end provided with an injection needle and a rear end provided with an actuation pushbutton, the device comprising a body (2) which can be dismountably coupled to the pen; an injection detection means determining when a drug injection is carried out; and a processing means configured for storing the date and time of the injection when the injection detection means detects that a drug injection is carried out, whereby the body is configured to be coupled to the pushbutton of the pen such that the pushbutton is actuated by pushing directly on the body, whereby the injection detection means is implemented as actuation detector configured for detecting said pushing action.

A drug injection needle comprises a puncturing needle part having a puncturing part capable of puncturing a body, a drug introducing needle part capable of communicating with the inside of the drug container, and a housing supporting the puncturing needle part and the drug introducing needle part to allow the liquid drug to flow between the needle parts. The outer diameter of the puncturing part is not more than 0.254 mm. The outer diameter of the drug introducing needle part is larger than at least that of the vicinity of the distal end of the puncturing part of the puncturing needle part, and a cutting edge is formed at the end of the drug introducing needle part for penetrating through an elastic member that is provided to seal the drug injection port of the drug container.

The invention discloses a negative pressure adsorption type hypodermic injection unit, which relates to a unit for carrying out hypodermic injection of insulin and other drugs, and consists of an adsorption device, an air compression device, a quick air releasing device and an injection syringe, wherein an absorber 1 is connected with an air compressor 3 through an air tube 2 so that the air in the absorber 1 can be quickly pumped out through the air compressor 3, negative pressure is formed in the absorber 1 so that the skin shrinks and has a bulge, and the bulge height of the skin can be adjusted through the air compressor 3. The injection syringe 4 is connected with the absorber 1 through syringe steps in a sealing way, when the skin shrinks and has the bulge, a syringe needle is automatically inserted into the skin, and then drug injection can be carried out. The quick air releasing device is formed by a rubber plug 5, when the rubber plug 5 is pulled out, the internal air pressure of the absorber 1 returns to the atmospheric pressure, the skin diastoles and returns to be smooth, and the syringe needle is automatically pulled out from the skin. The invention has the hypodermic injection characteristics of easy skin contraction, quick needle insertion, convenient injection and use, wide application scope and the like, and solves the problem that the old and the slimmer people are difficult to be injected with insulin and other subcutaneous injection drugs.

The invention provides a method for preparing high-purity beta elemene from natural plants containing the beta elemene such as curcuma zedoary (earthnuts or tubers of the curcuma zedoary), cedronella (fresh leaves of the cedronella), yellowtop (roots, stems, leaves, flowers and seeds of the yellowtop) and so on, which can improve the production efficiency from starting materials to the high-purity beta elemene and reduce production cost. Compared with the prior art, the method is mainly different in that the roots, stems, leaves, flowers and seeds of the natural plants are taken as raw materials; oleum volatile of specific parts of the natural plants is obtained by methods for extracting different oleum volatiles, and is distilled by molecular distillation method to remove compositions with high boiling points and non-volatile compositions; impurity compositions are removed by the ethanol extraction method and silver nitrate complex extraction method; and finally the beta elemene with the content between 95.0 and 99.9 percent is obtained through reduced pressure distillation or rectification. The bulk pharmaceutical chemicals not only can be prepared into oral dosing preparation such as emulsion oral liquid, self-emulsifying / self-microemulsifying capsules, soft capsules and so on, but also can be prepared into non-alimentary dosing preparation such as emulsion injection, liquid drugs injection, transdermal absorbent, lung sprays, suppository and so on. The method has the advantages of novel design, concise operating steps, mild operating conditions and improvement of the production efficiency of the beta elemene.

Objects are to ensure a required depressing force and puncture speed when a needle tube is punctured in the skin, and to be able to reliably situate a needle tip of a needle tube in the upper layer of skin. A needle injection assembly 2 includes a needle tube 5 having a needle tip 8 that can be punctured in a living body, a hub 6 that holds the needle tube 5, an adjustment section 12, a stabilizing section 13, and a puncture speed securing member 7. The adjustment section 12 is provided around the periphery of the needle tube 5 and has a needle projection surface 12a, from which the needle tip 8 of the needle tube 5 projects. The stabilizing section 13 extends from the hub 6, is disposed to surround the needle tube 5 and has an end face 13a that comes in contact with the skin when the needle tube 5 is punctured in the living body. The puncture speed securing member is provided at the adjustment section 12 or stabilizing section 13 such that the puncture speed securing member moves along the axial direction of the needle tube 5. The puncture speed securing member 7 is brought into contact with the skin ahead of the needle tip 8 of the needle tube 5 when the needle tube 5 is punctured in the living body and ensures the speed and depressing force as desired when the needle tube 5 is punctured in the living body.

Pen-type drug injection device and electronic add-on monitoring module for monitoring and logging dose setting and administration is described. The module comprises a processor and a sensor (e.g. optical or electromagnetic) for determining the quantity of medicament that has been delivered, wherein the sensor (201, 204) is arranged to detect movement of a drive screw (205) of the injection device during medicament delivery.

The invention relates to a ceftizoxime sodium drug injection powder and a preparation method thereof, as well as a synthetic method of bulk drug ceftizoxime sodium. The ceftizoxime sodium drug injection powder consists of 100% ceftizoxime sodium, wherein the ceftizoxime sodium is pretreated, and the pretreatment is aseptic refining and / or grinding. The ceftizoxime sodium drug has the advantages of high purity, almost no impurity, better and more stable quality, better clarity and the like; and the synthetic method of bulk drug ceftizoxime sodium has lower bulk cost, less synthesis technology difficulty, mild reaction condition, stable and reliable yield and quality, and high purity and yield of products.

A skin-patch type large volume medicament injection device (1) comprising an adhesive surface (21 / 23) for attachment to the skin and a plurality of contact sensors (24) configured to output a signal representing a degree of detachment of the device from the injection site, and an alarm and control function which outputs an alert to the user based on the signal received from the sensors and stops the injection in case the degree of detachment is too large to guarantee further save injection.

The invention discloses a drug and edible two-use fungus grey ramalic GF-932[Grifola frondosa (Dichs.ex Fr.) S.F.Gray] and producing method of grey ramalic beta-dextran, which is characterized by the following: applying in the tablet, soft capsule and hard capsule, liquid drugs injection and freeze dried; reserving in the China biological bacterial reserving management committee common microbe center with CGMCC No.1709 as reserving number.

A method for determining predicted failure rates of drug injection devices includes receiving a set of parameters that specify physical properties of (i) a syringe, and (ii) a liquid drug, and (iii) a drug injection device configured to deliver the liquid drug to a patient via the syringe. The method further includes receiving failure rate data that specifies a measured rate of failure of the drug injection device in response to various peak pressures within the syringe, applying the received set of parameters to a kinematic model of the drug injection device to determine a predicted peak pressure within the syringe, including determining the predicted peak pressure as a function of impact velocity of the liquid drug, determining a probability of failure of the drug injection device using (i) the received failure rate data and (ii) the predicted peak pressure, and providing an indication of the determined probability of failure to an output device.

A medical injection device is provided which includes a shield system and a syringe. The shield system includes a housing, a shield telescopically received in the housing and slidably coupled to the housing and a driver that pushes the syringe stopper to cause drug injection. The driver is equipped with sensing elements that automatically detect empty syringe. A spring resiliently urges the shield from a retracted position to an extended position shielding the needle. The syringe is coupled to the housing. The shield is positioned externally to the syringe and the driver. The shield includes flexible latches to keep its position relative to the housing during storage and use. The axial movement of the driver in respect to the syringe causes an automatic release of the spring by sensors when the syringe is empty, allowing the spring to move and lock the shield in the extended position after use.

Pen-type drug injection device (1) and attachable electronic add-on monitoring module (2) for monitoring and logging dose setting and administration, the module comprising a housing, an electromechanical switch arrangement (110), the electromechanical switch arrangement comprising a main body (111) and a switching member (113), the switching member having a protrusion (118) arranged to protrude from the main body so as to contact a surface of the injection device while the module is attached to the injection device, and a biasing member (115) biasing at least a part of the main body of the electromechanical switch arrangement against the injection device while the module is attached to the injection device.

The invention provides a drug injection device and dispensing equipment, and relates to the technical field of medical equipment. The drug injection device is designed to solve the problem of single function of an injection device of an existing dispensing system. The drug injection device comprises an upper turntable, a lower turntable, a plurality of containing cavities formed between the upperturntable and the lower turntable and a driving assembly used for driving the rotation of the lower turntable, wherein the upper turntable is provided with a plurality of openings uniformly distributed in the circumference of the upper turntable, the openings are communicated with the containing cavities respectively one to one, and the containing cavities are internally provided with injection assemblies. The dispensing equipment comprises the drug injection device. The drug injection device and the dispensing equipment have the advantages that the simultaneous preparation of a plurality of drugs in a plurality of drug bottles is achieved, and the preparation of the corresponding drug in each drug bottle is separate from one another and does not interfere with one another, thereby well overcoming the defect that the injection device of the existing dispensing system only achieves the preparation of one drug, and the function is more perfect.