The invention discloses a coordinated control method based on GPS synchronous fixed frequency for a micro-grid running in an isolated island. The method solves the problem of interactive influence between frequency stability and voltage stability and comprises the steps of 1, establishing a static droop curve of an adjustable power supply according to the maximum allowable voltage, rated working voltage and a maximum current limiting point; 2, establishing a current output response controller on the basis of first-order dynamic characteristics; 3, in order to achieve the purposes of improving system damping ratio and reasonably distributing power, establishing a typical scene droop coefficient optimization query base, and conducting dynamic optimization on droop coefficients; 4, determining adjustable power supply output of a current running scene; 5, establishing a combined optimization model of active power and reactive power, and adopting a Newton method to carry out multi-target solution; 6, determining the optimal power, voltage and current output. According to the coordinated control method based on the GPS synchronous fixed frequency for the micro-grid running in the isolated island, the synchronous fixed frequency of the micro-grid, the voltage stability and optimization control of the micro-grid, the on-site voltage control and power distribution of the micro-grid, and efficient optimization running of the micro-grid are achieved.