294 results about "Breast disease" patented technology

The present invention provides a method for diagnosing and detecting diseases associated with breast. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in breast diseases (BCAT) and antibodies binds to BCAT. The present invention provides that BCAT is used as targets for screening agents that modulates the BCAT activities. Further the present invention provides methods for treating diseases associated with breast.

The invention discloses a Chinese medicinal preparation for treating breast diseases and uterine fibroid and a preparation method thereof. The Chinese medicinal preparation is prepared by extracting and mixing the following raw materials in percentage by weight: 8 to 15 percent of Chinese thorowax root, 4 to 6 percent of turmeric root-tuber, 3 to 6 percent of pangolin, 4 to 6 percent of nutgrass galingale rhizome, 3 to 5 percent of thunbery fritillary bulb, 3 to 5 percent of snake gourd fruit, 3 to 4 percent of hemlock parsley, 3 to 5 percent of suberect spatholobus stem, 2 to 4 percent of red-rooted salvia root, 2 to 3 percent of common burreed rhizome, 2 to 3 percent of curcuma zedoary, 2 to 3 percent of frankincense, 2 to 3 percent of myrrh, 3 to 5 percent of rhizoma corydalis, 3 to 5 percent of turtle shell, 2 to 4 percent of spina gleditsiae, 2 to 3 percent of semen litchi, 5 to 6 percent of selfheal, 3 to 6 percent of Astragalus root, 2 to 4 percent of angelica, 2 to 3 percent of Atractylis ovate, 2 to 3 percent of white peony root, 2 to 3 percent of poria, and 2 to 3 percent liquorice. The Chinese medicinal preparation can be used for treating patients with hyperplasia of mammary glands, mamstitis or hysteromyoma, and has high clinical cure rate and good healing effect.

Disclosed is a method and apparatus for accomplishing a noninvasive screen for breast disease markers, including breast cancer markers and cytologically abnormal cells. Intraductal fluid is noninvasively aspirated using compression, heating and suction cycles. The removed sample is thereafter assayed for the presence of cytologically abnormal cells and / or one or more breast disease markers. In addition to the diagnostic applications of the disclosed method and apparatus, a therapeutic application is also contemplated wherein intraductal fluids are noninvasively aspirated using compression, heating and suction cycles to remove toxic buildups within the fluid.

The present invention provides compositions containing endoxifen, formulations and liposomes of endoxifen, methods of preparation of such agents and formulations, and use of such agents and formulations for the treatment of breast cancer and other breast diseases and diseases susceptible to endoxifen. In particular, the compositions of the present invention include liposomes, complexes, vesicles, emulsions, micelles and mixed micelles of endoxifen in which the compositions further contain any of a variety of neutral or charged lipids and desirably, cholesterol and cholesterol derivatives, sterols, Z- and E-guggulsterones, phospholipids, fatty acids, vitamin D, and vitamin E. The present invention also provides methods of preparing endoxifen. The present invention provides methods for treating and preventing breast cancer and other breast related diseases by administrating novel formulations or compositions comprising a therapeutically effective amount of endoxifen.

The invention discloses a time intensity characteristic-based computer aided method for diagnosing benign and malignant breast lesions, comprising the following steps of: selecting an image sequence layer with suspicious lesions from a DCE(Dynamic Contrast-Enhanced)-MRI (Magnetic Resonance Imaging) image sequence set; carrying out denoising and filtering treatment on each image layer and acquiring a photographic subtraction sequence of the layer; determining a time intensity curve according to the photographic subtraction sequence of the layer; analyzing the characteristic of the time intensity curve and giving out a diagnosis result of the layer, namely a preliminary diagnosis result of the lesion; and fusing diagnosis results of the time intensity curves for different layers to give out a final lesion diagnosis result. According to the time intensity characteristic-based computer aided method disclosed by the invention, by comprehensively analyzing the characteristic of the time intensity curve on each layer, the accuracy of benign and malignant diagnosis of the lesions can be greatly improved for assisting clinical diagnosis for breast diseases and further the misdiagnosis rate is reduced.

The invention discloses a system and method for three-dimensional breast X-ray and three-dimensional color Doppler ultrasound fusion imaging. The system for fusion imaging comprises a breast X-ray machine for collecting three-dimensional X-ray images of the breast, an ultrasonic machine for collecting three-dimensional ultrasound images of the breast and a collecting terminal for performing fusion treatment on the three-dimensional X-ray images and the three-dimensional ultrasound images of the breast so as to obtain a two-dimensional image group. The two-dimensional image group comprises two or more fused two-dimensional images. The collecting terminal is in communication connection with the breast X-ray machine and the ultrasonic machine. According to the system, the advantages of the X-ray technology and the color Doppler ultrasound technology are combined, so that the breast two-dimensional image group fusing X-ray and color Doppler ultrasound imaging information is obtained, and thus clinical doctors can make a diagnosis on breast diseases more accurately and more conveniently.

The invention provides a medicine for treating hyperplasia of mammary glands, mastodynia and general mammary diseases and a preparation method thereof, relating to the field of traditional Chinese medicine. At present, hormone replacement therapy is commonly used in western medicine, but the side effects are large, and the curative effects are dubious, however, traditional Chinese medicine has a good development prospect. The medicine comprises the following ingredients: 10-15 g of Chinese angelica, 9-15 g of rhizoma corydalis, 9-15 g of thunberg fritillary bulb, 9-15 g of cowherb seed, 9-15 g of Cyperus rotundus, 9-15 g of curcuma aromatica, 9-15 g of radix bupleuri, 10-15 g of turtle shell, 9-15 g of bighead atractylodes rhizome, 9-15 g of banksia rose, 9-15 g of Poria cocos, 6-9 g of gleditsia sinensis, and 9-15 g of motherwort. Experiments of pharmacodynamics,toxicology and clinical experiment prove that the medicine provided by the invention has the advantages of substantial curative effect, little toxic and side effect, convenient usage, low cost and the like.

The invention discloses a taxus chinensis-containing bra, which is made from taxus chinensis serving as a raw material. The taxus chinensis-containing bra selectively contains one or more of dandelion having effects of clearing heat and releasing toxin, removing swelling and masses and treating mastitis, nutgrass galingale rhizome having effects of regulating qi and relieving depression, regulation menstruation and relieving pain, and treating mammary swelling, orange leaf having an effect of treating hypochondriac pain and acute mastitis, rose having an effect of treating swollen breasts, and corydalis having effects of activating blood circulation to dissipate blood stasis and promoting circulation of qi and relieving pain. The invention has the advantages that: the taxus chinensis-containing bra has obvious effects of regulating qi and relieving pain, activating blood circulation to dissipate blood stasis, softening hardness to dissipate stagnation and preventing and treating breast diseases such as swollen breasts, mammary gland hyperplasia, breast fibroadenoma and the like, and can prevent and inhibit breast cancer.

The invention relates to a mammary gland electronic medical record entity recognition system based on multi-standard active learning, and the system is characterized in that the system comprises a preprocessing module; an entity identification module; and an active learning module. According to the invention, the active learning selection strategy for text sequence annotation is designed by considering three aspects of annotation data volume, sentence annotation cost and data sampling balance, so the total annotation workload is reduced. On the one hand, the system can be used for constructingsystems such as breast disease risk patient identification marks, disease medicine recommendation and auxiliary decision diagnosis, doctors are helped to improve the execution efficiency of breast disease standardized diagnosis and treatment, and scientific bases and suggested schemes are provided; on the other hand, doctors can be assisted in finding out potential abnormal conditions in the diagnosis and treatment process, the misdiagnosis and missed diagnosis rate is reduced, the curing probability of breast disease patients is increased, and important value is achieved for intelligent development of breast disease research.

The invention belongs to the field of an intelligent wearing technology, and specifically an intelligent corsage for detecting breast diseases. The intelligent corsage for detecting the breast diseases is provided with a signal acquisition module, a wireless communication module and a control module which are sequentially connected; the signal acquisition module comprises an infrared transmitter, an infrared receiver and a signal processor which are sequentially connected, wherein the signal processor is connected with the wireless communication module; the control module comprises a microprocessor, a memory and a buzzer, wherein the microprocessor is respectively connected with the memory and the buzzer, and the microprocessor is connected with the wireless communication module. Mammary abnormity is judged by acquiring the near infrared ray grey scale signals of mammary tissues through the intelligent corsage; by adopting the wireless communication module, an electronic circuit in the corsage can be reduced, the comfort of the corsage can be improved, and the life of washing and prolonging the corsage can be conveniently prolonged; and compared with the self-check of females through specific skills and annual periodic physical examination, the intelligent corsage is high in reliability and is capable of discovering the mammary abnormity.

The present invention relates to a Chinese medicine for curing mamary aggregation. It is a compound Chinese medicine preparation made up by using 11 Chinese medicinal materials of prunella spike, ligusticum root, silkworm, turtle shell, bupleurum root, red peony root and others.

The invention discloses a method for efficiently separating and purifying mammary epithelial cells. The method is suitable for a plurality of mammals. The mammary tissues of adult mammals, which are in the middle and later periods of gestation or in the lactation period, are collected through aseptic operation. According to the provided method, the separation and purification can be achieved in one step, the whole experiment is simple and efficient; the purification, which comprises repeated differential digestion and differential attachment, in the conventional method is eliminated, the purity of mammary epithelial cells obtained by the provided method can reach 98% or more, the obtained mammary epithelial cells can be continuously cultured in-vitro and passed down for 40 generations, and the lactating function of mammary epithelial cells is not affected. The obtained mammary epithelial cells can be applied to the researches on growth of mammary gland, lactating mechanism, mammary bioreactor, transgenic animals, mammary diseases, and the like.