32 results about "Fibroadenoma" patented technology

A cryosurgical system adapted for treatment of fibroadenomas within the breast of a patient. The system includes cryoprobes and a control system which operates the cryoprobes to accomplish freezing in two stages, including a high power freeze and a low power freeze.

A cryosurgical system adapted for treatment of fibroadenomas within the breast of a patient. The system includes cryoprobes and a control system which operates the cryoprobes to accomplish freezing in two stages, including a high power freeze and<custom-character file="US20040082943A1-20040429-P00999.TIF" wi="151.6" he="8.4" id="custom-character-00001" alt="text missing or illegible when filed" / >

The invention relates to a thermoacoustic, photoacoustic and ultrasonic three-mode breast tumor detection device and a thermoacoustic, photoacoustic and ultrasonic three-mode breast tumor detection method. The thermoacoustic, photoacoustic and ultrasonic three-mode breast tumor detection device comprises a pulse train generator, a microwave source, a laser source, an ultrasonic emitting source, acoupler, a detector, a data acquisition module and an image processing module, wherein a tissue to be detected is placed inside the coupler; energy of the microwave source, the laser source and the ultrasonic emitting source is radiated into the coupler; generated thermoacoustic, photoacoustic and ultrasonic signals are jointly received by the detector; then, the signals are acquired by the data acquisition module and transmitted into the image processing module; the image processing module reconstructs thermoacoustic, photoacoustic and ultrasonic images by a back-projection algorithm to obtain three-mode images; finally, the three-mode images are superposed and synthesized on the same image. The thermoacoustic, photoacoustic and ultrasonic three-mode breast tumor detection device integrates the advantages of respective single modes in one system, and can not only eliminate misdiagnosis of breast edema, inflammation and fibroadenoma, but also improve the accuracy of early breast cancerdetection through combination of multiple parameter indexes.

The invention provides a medicament for treating adenofibroma of breast and cyclomastopathy. The medicament is prepared by the following raw materials in portion by weight: 30 to 50 portions of Chinese thorowax, 50 to 70 portions of rhizoma cyperi, 10 to 30 portions of trigone, 50 to 70 portions of tulip, 30 to 50 portions of rhizoma arisaematis, 20 to 40 portions of seaweed, 20 to 40 portions of sea-tangle, 20 to 40 portions of radix codonopsitis, 20 to 40 portions of radix astragali, 20 to 40 portions of fritillary bulb, 30 to 50 portions of green tangerine orange peel, 20 to 40 portions of radix linderae, 50 to 70 portions of oyster, 10 to 30 portions of woodlouse, 10 to 30 portions of spina gleditsiae, 20 to 40 portions of rhizoma zedoariae, and 20 to 40 portions of radix curcumae. In the medicament, the Chinese medicines are compatible with each other, compact but not complex, and play the efficacies of promoting qi circulation and removing obstruction in the collateral, promoting blood circulation and removing obstruction in channels, resolving phlegm and softening hard masses, and can treat breast diseases perfectly. The medicament is mainly used for treating adenofibroma of breast and cyclomastopathy, and has good treatment effect and short treatment period.

A method for selectively heating cancerous conditions of the breast including invasive ductal carcinoma and invasive glandular lobular carcinoma, and pre-cancerous conditions of the breast including ductal carcinoma in-situ, lobular carcinoma in-situ, and intraductal hyperplasia, as well as benign lesions (any localized pathological change in the breast tissue) such as fibroadenomas and cysts by irradiation of the breast tissue with adaptive phased array focused microwave energy is introduced. Microwave energy provides preferential heating of high-water content breast tissues such as carcinomas, fibroadenomas, and cysts compared to the surrounding lower-water content normal breast tissues. To focus the microwave energy in the breast, the patient's breast can be compressed and a single electric-field probe, inserted in the central portion of the breast, or two noninvasive electric-field probes on opposite sides of the breast skin, can be used to measure a feedback signal to adjust the microwave phase delivered to waveguide applicators on opposite sides of the compressed breast tissue. The initial microwave power delivered to the microwave applicators is set to a desired value that is known to produce a desired increase in temperature in breast tumors. Temperature feedback sensors are used to measure skin temperatures during treatment to adjust the microwave power delivered to the waveguide applicators to avoid overheating the skin. The microwave energy delivered to the waveguide applicators is monitored in real time during treatment, and the treatment is completed when a desired total microwave energy dose has been administered. By heating and destroying the breast lesion sufficiently, lesions can be reduced in size and surrounding normal breast tissues are spared so that surgical mastectomy can be replaced with surgical lumpectomy or the lesions can be completely destroyed so that surgical mastectomy or lumpectomy is avoided.

A method of treating fibroadenomas with optimized freezing periods at a single freezing temperature and minimal thawing time between freezing periods, and a system for accomplishing the method.

A method of differentiating among the presence of ductal carcinoma in situ in the breast, benign fibroadenoma of the breast, and non-cancerous breast tissue in a subject is disclosed. The method comprises: measuring the concentration of at least one protein biomarker selected from a group of forty-nine differentially expressed proteins in the saliva of persons with DCIS, or benign fibroadenoma, or in persons who are cancer-free. The resulting test data is compared to a reference panel. From the comparison the presence in the subject of either ductal carcinoma in situ of the breast, or benign fibroadenoma of the breast is determined.

The invention discloses a nutritional breast patch and a preparation method thereof. The nutritional breast patch comprises nutrition liquid and an adhering membrane carrier. The nutrition liquid is mainly prepared by following raw materials including frankincense, rhizoma cyperi, fritillaria, Chinese angelica, green tangerine peels, ligusticum chuanxiong hort, ginseng, Chinese wolfberry, Chinese wolfberry seed oil, vitamin E, peony seed oil and hydrolyzed collagen. The nutritional breast patch has effects of tretching liver to smooth qi, promoting blood circulation to remove blood stasis and resolving hard lump, and has a good healthcare effect and / or a prevention effect for diseases of breast glands lobular hyperplasia, fibroadenoma of the breast, breast mass, breast dysplasia and the like.

The invention discloses a novel Chinese traditional medicine preparation for treating hyperplasia of mammary glands and a method for preparing the same, which belongs to the technical field of Chinese traditional medicine preparations. The Chinese traditional medicine preparation is extracted from the following natural Chinese herbal medicines in portion by weight: 10 to 20 portions of radix bupleuri, 12 to 24 portions of radix paeoniae alba, 10 to 20 portions of rhizoma atractylodis macrocephalae, 12 to 24 portions of chinese angelica, 12 to 24 portions of tuckahoe, 12 to 24 portions of gardenia, 5 to 10 portions of mint, 10 to 20 portions of liquorice, and the like, wherein the materials are prepared into capsules, granules or tablets according to the prior preparation process. Clinical studies prove that the novel Chinese traditional medicine preparation has the efficacies of soothing liver and qi stagnation, softening hardness to dissipate stagnation, and regulating vital energy and invigorating blood circulation, can be applied to treating diseases of hyperplasia of mammary glands, fibroadenoma of breast, and the like, has certain effect of improving the mood of a sufferer, increasing the appetite and improving sleeping, and has no obvious untoward effects and good safety; besides, the adoption of the novel Chinese traditional medicine preparation can lighten the economic burden of sufferers.

Devices, systems, and methods appropriate for use in medical training that include materials that better mimic natural human tissue are disclosed. In one aspect a polysiloxane mixture for simulating human biological tissue, especially human breast tissue, is disclosed. In another aspect, a method of manufacturing a biological tissue ultrasound phantom is disclosed. In another aspect, a human breast tissue models are disclosed. In some instances, the human breast tissue model includes at least one simulated pathological structure that simulates such pathologies as a cyst, a medullary carcinoma, a ductal carcinoma, an infiltrating scirrhus carcinoma, a lobular carcinoma, and a fibroadenoma.

The invention discloses a traditional Chinese medicinal composition for treating breast hyperplasia, an oral preparation and a preparation method of the oral preparation, wherein the traditional Chinese medicinal composition consists of ligusticum wallichii, salvia miltiorrhiza, pericarpium citri reticulatae viride, dried orange peel, radix bupleuri, angelica, radix paeoniae alba, liquorice root, cortex moutan, cape jasmine fruit, dandelion, fructus trichosanthis, frankincense and myrrh. The traditional Chinese medicinal composition for treating breast hyperplasia disclosed by the invention, which is prepared by combining various medicines in accordance with a prescription, has functions of discharging liver and relieving depression, nourishing blood and tonifying spleen, clearing heat and removing stasis, clearing heart and cooling blood, eliminating carbuncle and stagnation, promoting blood circulation and removing stasis, and relieving pain; the traditional Chinese medicinal composition is significant in curative effect on various breast hyperplasia caused by endocrine dyscrasia, qi stagnation and blood stasis, and is capable of treating both symptoms and root causes, with an effective rate above 90%; and meanwhile, the traditional Chinese medicinal composition has a significant effect on treating fibroadenoma of breast.

A method for selectively heating cancerous conditions of the breast including invasive ductal carcinoma and invasive glandular lobular carcinoma, and pre-cancerous conditions of the breast including ductal carcinoma in-situ, lobular carcinoma in-situ, and intraductal hyperplasia, as well as benign lesions (any localized pathological change in the breast tissue) such as fibroadenomas and cysts by irradiation of the breast tissue with adaptive phased array focused microwave energy is introduced. Microwave energy provides preferential heating of high-water content breast tissues such as carcinomas, fibroadenomas, and cysts compared to the surrounding lower-water content normal breast tissues. To focus the microwave energy in the breast, the patient's breast can be compressed and a single electric-field probe, inserted in the central portion of the breast, or two noninvasive electric-field probes on opposite sides of the breast skin, can be used to measure a feedback signal to adjust the microwave phase delivered to waveguide applicators on opposite sides of the compressed breast tissue. The initial microwave power delivered to the microwave applicators is set to a desired value that is known to produce a desired increase in temperature in breast tumors. Temperature feedback sensors are used to measure skin temperatures during treatment to adjust the microwave power delivered to the waveguide applicators to avoid overheating the skin. The microwave energy delivered to the waveguide applicators is monitored in real time during treatment, and the treatment is completed when a desired total microwave energy dose has been administered. By heating and destroying the breast lesion sufficiently, lesions can be reduced in size and surrounding normal breast tissues are spared so that surgical mastectomy can be replaced with surgical lumpectomy or the lesions can be completely destroyed so that surgical mastectomy or lumpectomy is avoided.

The invention discloses a traditional Chinese medicinal preparation for treating fibroadenoma of breast. The traditional Chinese medicinal preparation is prepared from vinegar-baked bupleurum root, rhizoma cyperi, curcuma tuber, fiveleaf akebia fruit, Chinese yew, trichosanthes kirilowii Maxim, prunella vulgaris, laminaria japonica, Pinellia ternata, dried orange peel, pangolin, Poria cocos, Arisaema cum Bile, bushy sophora, Zhejiang fritillaria bulb, fried white peony root, Chinese angelica, fried atractylodes, rabdosia rubescens, barbat skullcap, pseudobulubs cremastrae seu pleiones and Radix Glycyrrhizae according to a certain weight ratio. The traditional Chinese medicinal preparation has effects of soothing the liver and resolving depression, softening hardness and dissipating binds and drying damp and eliminating phlegm, and has remarkable treatment effect.

The invention relates to the technical field of traditional Chinese medicines and particularly relates to a traditional Chinese medicine composition for treating breast diseases as well as a preparation method and a breast patch thereof. The traditional Chinese medicine composition is prepared from herba taraxaci, fructus forsythiae, frankincense, euphorbia lunulata, caulis lonicerae, herba houttuyniae, flos caryophylli, radix aucklandiae, radix astragali seu hedysari, fructus trichosanthis, radix trichosanthis, Chinese honeylocust spine, tetrapanax papyriferus, rhizoma atractylodis, radix linderae, seed of garden balsam, radix cudramiae, semen persicae, cortex magnoliae officinalis, rhizoma coptidis, rhizoma zingiberis, radix angelicae pubescentis, radix angelicae lateralis preparata and gynura divaricata. The traditional Chinese medicine composition aims to the diseases and syndromes based on the knowledge and research of the modern novel medicine research mode; 24 traditional Chinese medicines are combined according to the compatibility theory of assistant and guide; the clinical research shows that the traditional Chinese medicine composition is capable of effectively treating multiple breast diseases such as mastitis, breast lump, breast hyperplasia, fibroadenoma of breast, lactocele and breast cancer. The clinical test and research show that the traditional Chinese medicine composition is capable of effectively treating multiple breast diseases.

A Chinese medicine in the form capsule for treating mastoplasia and mastofibroma is prepared from 12 Chinese-medicinal materials including scrophularia root, red sage root, dandelion herb, white peony root, etc. Its preparing process is also disclosed.

The invention relates to traditional Chinese medicine paste for treating a pain. The traditional Chinese medicine paste can effectively solve the pharmacy problem of treatment of the pain. The technical scheme is as follows: the traditional Chinese medicine paste is prepared from the following materials by weight: 28-32g of radix aconiti kusenzoffii, 28-32g of radix aconite, 28-32g of cortex cinnamomi, 13-17g of asarum, 18-22g of rhizoma zingiberis, 13-17g of clove and 3-5g of menthol as crude drugs and is prepared by the following steps of: respectively crushing the radix aconiti kusenzoffii, the radix aconite, the cortex cinnamomi, the asarum, the rhizoma zingiberis and the clove are by an 80-100mesh sieve, and evenly mixing to obtain fine drug powder; adding the menthol; blending the materials into viscous paste by white spirit of which the volume concentration is 50-65% at the temperature of 15-37 DEG C; and attaching the traditional Chinese medicine paste to the pain part when being used, and effectively treating various pain illnesses, such as various tumor pains of internal organs, pains in neck, shoulder, waist and lower extremities, tenosynovitis, diffuse idiopathic skeletal hyperostosis, and the pains caused by expanded tissue of various subdermal cysts, fibroadenoma of breast, thyrophyma and the like. The traditional Chinese medicine paste is good in curative effect, free of toxic and side effects, convenient and simple to take, safe and reliable.

The invention relates to a traditional Chinese medicine composition for treating mammary fibroadenoma. The traditional Chinese medicine composition is prepared from the following raw medicinal materials: 8-12 g of radix bupleuri, 8-12 g of curcuma tuber, 8-12 g of green tangerine peel, 8-12 g of Sinapis alba, 13-18 g of cowherb seed, 13-18 g of Zhejiang fritillaria bulb, 10-15 g of Chinese angelica, 13-18 g of Radix Astragali, 13-18 g of Radix Codonopsis, 10-15 g of radix paeoniae rubra, 10-15 g of Fructus Forsythiae, 4-7 g of Uniflower Swisscentaury Root, 15-25 g of spatholobus stem, 10-20 g of radish seed, 10-20 g of stir-fried millet sprout, 4-7 g of banksia rose, 10-15 g of corydalis tuber, 10-15 g of toosendan fruit, 10-15 g of Cortex moutan, 10-15 g of dandelion, 8-12 g of donkey-hide gelatin and 4-7 g of licorice. The traditional Chinese medicine composition has advantages of simple preparation, wide medicinal herbs resource and low cost. By water decoction for medication, the traditional Chinese medicine composition has efficacy of activating blood circulation to dissipate blood stasis, softening hardness and dissipating binds, clearing away heat and toxic materials, invigorating blood circulation and softening hardness and reinforcing qi and nourishing blood, can be used for effectively treating mammary fibroadenoma, has definite therapeutic effect and has high cure rate. By the use of the traditional Chinese medicine composition, mammary fibroadenoma is not easy to recur. The traditional Chinese medicine composition has no toxic or side effect.

The mastoproliferation treating Chinese medicine is prepared with ten kinds of Chinese medicinal materials including epimedium, astragalus root, bupleurum root, angelica, curcuma root, kelp, etc. The Chinese medicine of the present invention has the functions of soothing the liver, alleviating mental depression, softening the dry feces, dissipating mass, regulating vital energy and promoting blood circulation, and is used in treating acute mastitis, mastoproliferation, fibroadenoma of breast, male's mammary development and other diseases.

A cryosurgical system adapted for treatment of fibroadenomas within the breast of a patient. The system includes cryoprobes and a control system which operates the cryoprobes to accomplish freezing in two stages, including a high power freeze and a low power freeze.

A method of treating fibroadenomas with optimized freezing periods at a single freezing temperature and minimal thawing time between freezing periods, and a system for accomplishing the method.

A method of differentiating among the presence of ductal carcinoma in situ in the breast, benign fibroadenoma of the breast, and non-cancerous breast tissue in a subject is disclosed. The method comprises: measuring the concentration of at least one protein biomarker selected from a group of forty-nine differentially expressed proteins in the saliva of persons with DCIS, or benign fibroadenoma, or in persons who are cancer-free. The resulting test data is compared to a reference panel. From the comparison the presence in the subject of either ductal carcinoma in situ of the breast, or benign fibroadenoma of the breast is determined.

The invention discloses a nutritional breast patch and a preparation method thereof. The nutritional breast patch comprises nutrition liquid and an adhering membrane carrier. The nutrition liquid is mainly prepared by following raw materials including frankincense, rhizoma cyperi, fritillaria, Chinese angelica, green tangerine peels, ligusticum chuanxiong hort, ginseng, Chinese wolfberry, Chinese wolfberry seed oil, vitamin E, peony seed oil and hydrolyzed collagen. The nutritional breast patch has effects of tretching liver to smooth qi, promoting blood circulation to remove blood stasis and resolving hard lump, and has a good healthcare effect and / or a prevention effect for diseases of breast glands lobular hyperplasia, fibroadenoma of the breast, breast mass, breast dysplasia and the like.

The present invention relates to peptides that inhibit the excessive production and / or accumulation of an extracellular matrix in an organ or tissue. The peptides of the invention have the general formula sequence Xa-Leu-Gln-Gly-Xb (SEQ ID NO: 1) wherein Xa is selected from the group consisting of Pro-Gly, Gly and Ac-Gly and Xb is selected from the group consisting of Glu and Glu-NH2, which peptides are capable of inhibiting excessive production and excessive accumulation of extracellular matrix in organs or tissues in the form of linear peptides and cyclic peptides. In particular, the peptides disclosed herein are useful for the treatment of fibrotic disorders characterized by excessive accumulation of extracellular matrix, such as liver fibrosis, cirrhosis, pulmonary fibrosis, chronic respiratory failure, cardiac fibrosis, ischemic heart disease, heart failure, diabetic nephropathy, glomerulonephritis, myelofibrosis, and various types of cancers, such as liver fibrosis, liver cirrhosis, pulmonary fibrosis, chronic respiratory failure, cardiac fibrosis, ischemic heart disease, heart failure, diabetic nephropathy, glomerulonephritis, myelofibrosis, and the like. Such as breast cancer, uterine cancer, prostate cancer, pancreatic cancer, colon cancer, skin cancer, blood cell cancer, central nervous system cancer, fibromyoma, fibroma, fibroadenoma and fibrosarcoma.

A Chinese medicine in the form capsule for treating mastoplasia and mastofibroma is prepared from 12 Chinese-medicinal materials including scrophularia root, red sage root, dandelion herb, white peony root, etc. Its preparing process is also disclosed.

The present invention discloses a Chinese medicine for external application for quickly curing hyperosteogeny of cervical vertebrae, hyperosteogeny of lumbar vertebrae, hyperplasia of lobuli glandulae mammariae and fibroadenoma of breast with obvious therapeutic effect. Said Chinese medicine is made up by using 11 Chinese medicinal materials of clematis root, speranskia / balsam, paederia, trichosanthes seed, dahurian angelica root, carthamus flower, silkworm and others as raw material, mixing them and grinding them. Said invention also provides its application method.

The invention discloses a medicine for conditioning myoma, mammary gland and menstruation and a preparation method thereof. The medicine for conditioning myoma, mammary gland and menstruation is prepared from the following raw materials in parts by weight: 23 to 34 parts of cassia twig, 18 to 25 parts of radix aconiti lateralis praeparata, 17 to 24 parts of herba asari, 16 to 22 parts of root of paris polyphylla, 13 to 20 parts of rhizoma sparganii, 14 to 23 parts of curcuma zedoary, 10 to 16 parts of centipede, 8 to 14 parts of herb of patrinia heterophylla bunge, 6 to 13 parts of turtle shell, 4 to 9 parts of earthworm, 3 to 6 parts of dung beetle, 2 to 4 parts of woodlouse, 4 to 9 parts of frankincense, 6 to 12 parts of myrrh, 3 to 5 parts of calcinated pig iron, 7 to 13 parts of radixbupleuri, 3 to 7 parts of musk, 4 to 11 parts of borneol and 35 to 48 parts of honey. The main traditional Chinese medicine preparation with the effects of activating blood, promoting qi circulation and resolving hard lump is used for treating hysteromyoma; the use effect proves that after the medication, the hysteromyoma is controlled to different degrees; a tumor body is reduced; the symptoms ofirregular menstruation, waist and abdomen pain, hyperplasia of mammary glands, fibroadenoma of breast, intimitis, ovarian cyst and the like are obviously relieved.

The invention discloses a novel Chinese traditional medicine preparation for treating hyperplasia of mammary glands and a method for preparing the same, which belongs to the technical field of Chinese traditional medicine preparations. The Chinese traditional medicine preparation is extracted from the following natural Chinese herbal medicines in portion by weight: 10 to 20 portions of radix bupleuri, 12 to 24 portions of radix paeoniae alba, 10 to 20 portions of rhizoma atractylodis macrocephalae, 12 to 24 portions of chinese angelica, 12 to 24 portions of tuckahoe, 12 to 24 portions of gardenia, 5 to 10 portions of mint, 10 to 20 portions of liquorice, and the like, wherein the materials are prepared into capsules, granules or tablets according to the prior preparation process. Clinicalstudies prove that the novel Chinese traditional medicine preparation has the efficacies of soothing liver and qi stagnation, softening hardness to dissipate stagnation, and regulating vital energy and invigorating blood circulation, can be applied to treating diseases of hyperplasia of mammary glands, fibroadenoma of breast, and the like, has certain effect of improving the mood of a sufferer, increasing the appetite and improving sleeping, and has no obvious untoward effects and good safety; besides, the adoption of the novel Chinese traditional medicine preparation can lighten the economicburden of sufferers.

The invention discloses a traditional Chinese medicine composition for treating fibroadenoma of breasts.The traditional Chinese medicine composition is prepared from raw medicinal herb materials: by weight, 10-30 parts of Herba Salviae Chinensis, 10-20 parts of Herba Menthae, 5-15 parts of Nidus Vespae, 10-20 parts of Spica Prunellae, 10-20 parts of Sargassum, 10-30 parts of Concha Ostreae, 5-15 parts of edible tulip, 10-20 parts of Fructus Gardeniae, 10-20 parts of Herba Epimedii, 5-15 parts of Rhizoma Dioscorea Bulbifera, 10-20 parts of Fructus Corni, 10-20 parts of Rhizoma Curcumae, 5-15 parts of Pericarpium Citri Reticulatae, 10-20 parts of Fructus Citri Sarcodactylis, 10-20 parts of Cortex Moutan, 5-15 parts of Boswellia Carteri, 10-20 parts of Herba Houttuyniae, 10-20 parts of Cortex Eucommiae, 10-20 parts of Caulis Spatholobi, 10-20 parts of Oldenlandia Diffusa and 5-15 parts of Folium Citri Reticulatae.The traditional Chinese medicine composition has efficacy of soothing liver to remove depression, activating blood to remove stasis, stimulating qi, reliving pain and softening hard lump to dissipate stagnation, and particularly has remarkable curative effect in treating fibroadenoma of breasts with reliable action.