The invention discloses an on-board computer safety protection box for driverless automobiles, including a base, an expansion spring, a connecting rod, fixing rods, a fan, a motor, a mounting bracket,a damping spring, a baffle, a stop block, a slider and a control panel. A placement groove is arranged on the top of the base, a box body is arranged in the placement groove, through holes are equidistantly arranged at the bottom of the box body, the mounting bracket is fixed on the inner part of the box body, the motor is fixed on the top of the mounting bracket, the output shaft of the motor passes through the side wall of the mounting bracket and is fixedly provided with a fan, the fixing rods are symmetrically arranged on both sides of that placement groove, the top end of each fixing rodis rotatably connected with the base through a hinge. The box body can be damped by the interaction of a limit spring, the expansion spring and the damping spring, the box is simple in structure andconvenient in operation, the stability of the device is increased, the vibration of the device is damped, and internal parts are prevented from being damaged.