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39results about How to "The synthesis process is simple and green" patented technology

Preparation method of injectable natural polysaccharide self-healing hydrogel

The invention relates to a preparation method of injectable natural polysaccharide self-healing hydrogel. The preparation method of the injectable natural polysaccharide self-healing hydrogel comprises the following steps: firstly synthesizing water soluble N-carboxyethyl chitosan by carrying out a Michael addition reaction on acrylic acid and chitosan, carrying out an oxidization reaction on sodium periodate and sodium alginate to obtain oxidized sodium alginate, then carrying out a dehydration condensation reaction on N-carboxyethyl chitosan and oxidized sodium alginate and on adipic dihydrazide and oxidized sodium alginate in a phosphate buffer liquid at the temperature of 37 DEG C, so as to respectively generate invertible imine bond and acylhydrazone bond, and finally preparing injectable natural polysaccharide macromolecular hydrogel with self-healing property. The preparation method of the injectable natural polysaccharide self-healing hydrogel has the advantages that a synthetic process of the injectable self-healing hydrogel is simple and green, reaction conditions are mild, the injectable self-healing hydrogel can form gel in a physiological environment and has self-healing capability, and the injectable self-healing hydrogel has a good application prospect in the fields of drug sustained release and the like.
Owner:XI AN JIAOTONG UNIV

Green method for increasing enzymolysis efficiency of cellulose in rice straws through stepwise pretreatment with two deep co-melting solvents

The invention belongs to the fields of utilization of lignocelluloses and energy and chemical industry application, and discloses a green method for increasing enzymolysis efficiency of cellulose in rice straws through stepwise pretreatment with two deep co-melting solvents. The method includes the steps of: with one deep co-melting substance as a solvent, pre-treating the rice straws, and performing filtration and separation to obtain a residue; drying the residue and pre-treating the residue with the other one deep co-melting solvent in the same way, thus finally obtaining pre-treated rice straws; enzymolyzing the rice straw residue, as a substrate, with cellulase to finally obtain a saccharide liquid mainly comprising glucose. The method increases the enzymolysis efficiency of the rice straws, increases yield of fermentable reduced saccharide (glucose), overcomes defects that an ionic liquid pretreatment process is high in cost and is not environment-friendly, and also solves a problem of poor pretreatment effect with single deep co-melting solvent. The method also expands application range and increases utilization rate of some green deep co-melting solvents.
Owner:GUANGDONG UNIV OF TECH

Green method for increasing cellulose enzymolysis efficiency in rice straws by utilizing lactic acid/guanidine hydrochloride to extract hemicellulose

The invention belongs to the fields of lignocellulose utilization and energy and chemical application, and discloses a green method for increasing a cellulose enzymolysis efficiency in rice straws by utilizing lactic acid / guanidine hydrochloride to extract hemicellulose. The green method includes: taking the lactic acid / the guanidine hydrochloride as a solvent to preprocessing the rice straws, filtering and separating to obtain residues, and drying to obtain preprocessed rice straws; taking the rice straw residues as a base material, and subjecting the base material to enzymolysis by cellulose so as to obtain a liquid sugar which mainly comprises glucose. The green method has the advantages that the enzymolysis efficiency of the rice straws can be increased effectively, a yield rate of fermentable reducing sugar is increased, and the defects of high cost and environmental unfriendliness of an ionic liquid preprocessing process are overcome.
Owner:GUANGDONG UNIV OF TECH

N,N-coordinated palladium complex with meta-carborane ligand and preparation and application of palladium complex

The invention relates to an N,N-coordinated palladium complex with a meta-carborane ligand and preparation and application of the palladium complex. A preparation method of the palladium complex comprises the following steps that (1) an n-BuLi solution is added into a meta-carborane solution and then a reaction is performed at a room temperature for 30-60 min; (2) 3-chloromethylpyridine is added and reacts at the room temperature for 3-5 h; (3) PdCl2 is added and reacts at the room temperature for 2-5 h, and the palladium complex is obtained through post-treatment; and the palladium complex isused for catalyzing an arylamine formylation reaction to prepare an arylamine formamide compound. Compared with the prior art, the synthesis process of the palladium complex is simple and green, andhas excellent selectivity and a high yield; and the palladium complex has the characteristics such as stable physicochemical properties and thermal stability, and exhibits excellent catalytic activityin the arylamine formylation reaction.
Owner:SHANGHAI APPLIED TECHNOLOGIES COLLEGE

Composite photocatalyst doped in heterojunction interface and preparation method

The invention discloses a composite photocatalyst doped in a heterojunction interface and a preparation method. The prepared Bi12O17Cl2 / g-C3N4 composite photocatalyst doped in a heterojunction interface has extremely strong capability in converting carbon dioxide into methane under visible light. Since g-C3N4 and Bi12O17Cl2 nanosheets are adopted to be combined, a large-area heterojunction can be more easily formed, and thereby the separation of current carriers is promoted; by thermal diffusion, bismuth atoms on Bi12O17Cl2 at the heterojunction interface are successfully doped into a g-C3N4 crystal lattice, consequently, a super strong electric field at the heterojunction interface is induced, and super performance in reducing carbon dioxide under the visible light is achieved; the extremely large specific surface area and countless pores of porous g-C3N4 provide convenience for interface doping; the flow direction of current carriers is successfully controlled by matched band-gap structure and interface doping, selectively reducing carbon dioxide into methane is realized, and the recyclability of the photocatalyst is enhanced; material synthesis is simple and green, the scale is large, and the industrial application prospect is good.
Owner:HUAIBEI NORMAL UNIVERSITY

Synthesis method of pyrrole[1,2-a]quinoxaline derivative

The invention relates to a synthesis method of a pyrrole [1,2a] quinoxaline derivative. The method comprises the steps: dissolving a cuprous complex, 2-bromoaniline, a pyrrole formaldehyde compound and an alkali in an organic solvent, carrying out a reaction, and carrying out separation and purification to obtain the pyrrole[1,2a] quinoxaline derivative, wherein the molar ratio of the cuprous complex to the 2-bromoaniline to the pyrrole formaldehyde compound to the alkali is (0.01-0.03): 1.0: 1.0: 1.5, the reaction temperature is 50-65 DEG C, and the reaction time is 6-8 hours. Compared with the prior art, the method has the advantages of mild reaction conditions, high yield, high substrate universality, less waste and the like.
Owner:SHANGHAI INST OF TECH

Ruthenium complex containing carboranyl benzimidazole structure as well as preparation method and application of ruthenium complex

The invention relates to a ruthenium complex containing a carboranyl benzimidazole structure as well as a preparation method and application of the ruthenium complex. The preparation method of the ruthenium complex comprises the following steps: 1) adding a n-BuLi solution into a carborane solution, and performing a reaction at room temperature for 30-60 min; 2) adding bromobenzimidazole, and performing a reaction at room temperature for 6-8 h; and 3) adding [(p-cymene)RuCl2]2, performing a reaction at room temperature for 3-5 h, and performing post treatment to obtain the ruthenium complex. The ruthenium complex is used to catalyze self-oxidative coupling of primary amines to prepare imine compounds. Compared with the prior art, the method provided by the invention uses the dinuclear ruthenium compound [(p-cymene)RuCl2]2 as a raw material, and the [(p-cymene)RuCl2]2 is reacted with the n-BuLi and o-carbonboryl benzimidazole to obtain the bivalent half-sandwich ruthenium complex containing the o-carbonboryl benzimidazole structure; and the ruthenium complex provided by the invention has stable physicochemical properties and thermal stability, is still stable at high temperature of300 DEG C, has a simple and green synthetic process, and exhibits excellent activity in the reaction of catalyzing the self-oxidative coupling of primary amines to prepare the imine compounds.
Owner:SHANGHAI INST OF TECH

Nuclear magnetic imaging and photodynamic/chemotherapy degradable silicon-based nano diagnosis agent and preparation method thereof

The invention belongs to the field of nano material preparation and biological medical application and particularly relates to a nuclear magnetic imaging and photodynamic / chemotherapy degradable silicon-based nano diagnosis agent and a preparation method thereof. The nano diagnosis agent disclosed by the invention is a SiO2-TA-Mn<+>-medicine-PEI compound nano particle; under a low pH and high GSHenvironment stimulation, a TA-Mn<+> structure in the compound nano particle can perform protonation and reduction reaction, a net structure is deconstructed, and medicine and metal ions for nuclear magnetic imaging are released out. Therefore, the nuclear magnetic imaging and photodynamic / chemotherapy degradable silicon-based nano particle nano diagnosis agent disclosed by the invention has the characteristics that the SiO2-TA-Mn<+>-medicine-PEI compound nano particle nano diagnosis agent has tumor position degradation response, magnetic resonance imaging, medicine response control release andthe like, and photodynamic therapy and chemotherapy combined synergistic oncotherapy under nuclear magnetic resonance imaging guidance is achieved.
Owner:FUZHOU UNIV

Application of palladium complex to fatty amine formylation reaction

The invention relates to application of a palladium complex to a fatty amine formylation reaction. A N,N-coordinated palladium complex containing a meta-carbobane ligand is used as a catalyst, N,N-dimethyl formamide is used as a formylating reagent and a solvent to catalyze the fatty amine formylation reaction to prepare a fatty amine carboxamide compound. Compared with the prior art, the N,N-coordinated divalent palladium complex containing the metacarbanyl ligand in the application is high in catalytic activity under mild conditions and can catalyze the formylation reaction of a fatty amine.DMF is further used as a formylating reagent and a solvent, and is inexpensive, low in toxicity, easy to separate and high in yield (88-96%).
Owner:SHANGHAI INST OF TECH

Application of dinuclear rhodium complex in fatty amine N-methylation reaction

The invention relates to application of a dinuclear rhodium complex in a fatty amine N-methylation reaction. The dinuclear rhodium complex is taken as a catalyst, CH3I is taken as a methylation reagent, and the fatty amine N-methylation reaction is catalyzed in an organic solvent for preparing a fatty amine N-methylation derivative. Compared with the prior art, according to the application of thedinuclear rhodium complex, the dinuclear rhodium complex has high catalytic activity at the indoor temperature and can be used for catalyzing the fatty amine N-methylation reaction for preparing the fatty amine N-methylation derivative, according to the catalytic reaction, the yield (90-97%) is high, and the reaction conditions are mild; participation of strong alkali is not needed, all the reagents have stable performance for air and water, the requirements for reaction equipment are low, and the dinuclear rhodium complex has a wide industrial application prospect.
Owner:SHANGHAI INST OF TECH

Palladium complex containing ortho-position carborane based benzimidazole structure, preparation method and application thereof

The invention relates to a palladium complex containing an ortho-position carborane based benzimidazole structure, a preparation method and application thereof. The palladium complex is prepared by the following method of: dropwise adding an n-BuLi solution into a carborane solution and carrying out stirring reaction, then adding bromo-benzimidazole for continuous reaction, then adding PdCl2 intoa reaction system for continuous reaction, performing separation at the end of the reaction to obtain a palladium complex containing an ortho-position carborane based benzimidazole structure, and applying the complex to catalyzing the reaction of alkyne, carboxylic acid and olefin to prepare the alpha-methylene-gamma-butyrolactone compounds by a one-pot method. Compared with the prior art, the palladium complex disclosed by the invention is high in catalytic efficiency, and the lactone compound can be synthesized by utilizing simple and cheap raw materials under mild conditions.
Owner:SHANGHAI INST OF TECH

Iridium complex containing carboryl benzimidazole structure and its preparation method and application

The invention relates to an iridium complex containing a carboryl benzimidazole structure and a preparation method and application thereof. The preparation method of the iridium complex comprises the following steps: 1) adding the n-BuLi solution to the carborane solution, and then React at room temperature for 30-60min; 2) Add bromobenzimidazole and react at room temperature for 6-8h; 3) Add [Cp*IrCl 2 ] 2 , and react at room temperature for 3‑5h, after post-treatment to obtain the iridium complex; the iridium complex is used to catalyze the asymmetric reduction of aryl ketones to prepare chiral alcohols. Compared with prior art, the present invention uses binuclear iridium compound [Cp*IrCl 2 ] 2 As a raw material, it is reacted with n-BuLi and ortho-carboryl benzimidazole to obtain a trivalent iridium complex containing an ortho-carboryl benzimidazole structure. The iridium complex has stable physical and chemical properties and Thermal stability, and the synthesis process is simple and green. It catalyzes the asymmetric reduction reaction of aryl ketones to synthesize chiral alcohols under mild conditions. It has excellent catalytic activity, enantioselectivity and high yield.
Owner:SHANGHAI INST OF TECH

Ruthenium complex containing carboryl benzimidazole structure and its preparation method and application

The invention relates to a ruthenium complex containing a carboranyl benzimidazole structure as well as a preparation method and application of the ruthenium complex. The preparation method of the ruthenium complex comprises the following steps: 1) adding a n-BuLi solution into a carborane solution, and performing a reaction at room temperature for 30-60 min; 2) adding bromobenzimidazole, and performing a reaction at room temperature for 6-8 h; and 3) adding [(p-cymene)RuCl2]2, performing a reaction at room temperature for 3-5 h, and performing post treatment to obtain the ruthenium complex. The ruthenium complex is used to catalyze self-oxidative coupling of primary amines to prepare imine compounds. Compared with the prior art, the method provided by the invention uses the dinuclear ruthenium compound [(p-cymene)RuCl2]2 as a raw material, and the [(p-cymene)RuCl2]2 is reacted with the n-BuLi and o-carbonboryl benzimidazole to obtain the bivalent half-sandwich ruthenium complex containing the o-carbonboryl benzimidazole structure; and the ruthenium complex provided by the invention has stable physicochemical properties and thermal stability, is still stable at high temperature of300 DEG C, has a simple and green synthetic process, and exhibits excellent activity in the reaction of catalyzing the self-oxidative coupling of primary amines to prepare the imine compounds.
Owner:SHANGHAI INST OF TECH

Method for synthesizing beta-(N-pyrazolyl) ketone compound through base catalysis

The invention relates to a method for synthesizing a beta-(N-pyrazolyl) ketone compound by base catalysis, which comprises the following steps of dissolving pyrazole and alpha, beta-unsaturated ketonein an organic solvent, adding base, reacting at a room temperature for 6-12 hours, and separating and purifying to obtain the beta-(N-pyrazolyl) ketone compound. Compared with the prior art, the method has the advantages of simple and green synthesis process, excellent selectivity, higher yield and wide substrate range, and has the wide application value in the fields of biology, pharmaceutical chemistry industry and the like.
Owner:SHANGHAI INST OF TECH

Single-phase samarium titanate nano-powder prepared by using solution method, and method for preparing single-phase samarium titanate nano-powder

The invention relates to single-phase samarium titanate nano-powder prepared by using a solution method, and a method for preparing the single-phase samarium titanate nano-powder. The method comprisesthe following steps: firstly dispersing a samarium source and a titanium source into a solvent according to a molar ratio of 1 to (1.1-1.3) to obtain a solution A; adjusting the pH value of the solution A to be neutral to obtain a milk-white mixed solution B; separating the milk-white mixed solution B to obtain white powder; drying the powder obtained in the third step, and then calcining to obtain the single-phase samarium titanate nano-powder. According to the method, the aim of accurately controlling the stoichiometric ratio of ternary Sm-Ti-O chemical elements is achieved by fully dissolving and dispersing the samarium source and the titanium source in a solvent medium as well as mixing and reacting the samarium source and the titanium source at an atomic scale, so that other impurities are prevented from appearing, and the aim of preparing the single-phase Sm2Ti2O7 is further realized.
Owner:成都莒纳新材料科技有限公司

A heterojunction interface doped composite photocatalyst and its preparation method

The invention discloses a composite photocatalyst doped in a heterojunction interface and a preparation method. The prepared Bi12O17Cl2 / g-C3N4 composite photocatalyst doped in a heterojunction interface has extremely strong capability in converting carbon dioxide into methane under visible light. Since g-C3N4 and Bi12O17Cl2 nanosheets are adopted to be combined, a large-area heterojunction can be more easily formed, and thereby the separation of current carriers is promoted; by thermal diffusion, bismuth atoms on Bi12O17Cl2 at the heterojunction interface are successfully doped into a g-C3N4 crystal lattice, consequently, a super strong electric field at the heterojunction interface is induced, and super performance in reducing carbon dioxide under the visible light is achieved; the extremely large specific surface area and countless pores of porous g-C3N4 provide convenience for interface doping; the flow direction of current carriers is successfully controlled by matched band-gap structure and interface doping, selectively reducing carbon dioxide into methane is realized, and the recyclability of the photocatalyst is enhanced; material synthesis is simple and green, the scale is large, and the industrial application prospect is good.
Owner:HUAIBEI NORMAL UNIVERSITY

Method for catalytically synthesizing aryl oxazole compound by using nickel complex

The invention relates to a method for catalytically synthesizing an aryl oxazole compound by using a nickel complex, which comprises the following steps: by taking the nickel complex containing an ortho-carborane benzothiazole structure as a catalyst and taking benzoxazole and aryl halide compounds as raw materials, carrying out oxidative coupling reaction at room temperature in the presence of alkali, thereby obtaining the aryl oxazole compound. The aryl oxazole compound is obtained. Compared with the prior art, the method has the advantages that the nickel complex containing the ortho-carborane benzothiazole structure is utilized to efficiently catalyze the multi-component reaction at room temperature to synthesize the aryl oxazole compound through the one-pot method, synthesis of the aryl oxazole compound at room temperature is achieved, the using equivalent of the catalyst is low, the reaction condition is mild, the substrate universality is high, raw materials are low in price and easy to obtain, and the method is suitable for industrial production. The product yield is high.
Owner:SHANGHAI INST OF TECH

Method for synthesizing enamine under catalysis of palladium imine complex containing pyridine ligands

The invention relates to a method for synthesizing enamine under catalysis of a palladium imine complex containing pyridine ligands. The method comprises steps as follows: phenylacetylene and secondary amine are taken as raw materials, the palladium imine complex containing the pyridine ligands is taken as a catalyst, a hydroamination reaction is performed in a solvent, aftertreatment is performed, and enamine is obtained. Compared with the prior art, the method for preparing enamine compounds through the hydroamination reaction of phenylacetylene under the catalysis of a divalent palladium imine complex containing the pyridine ligands is provided, raw materials are simple and easy to obtain, a synthesis process is simple and green, the method has excellent selectivity and high yield, theatom economy is high, three wastes are reduced, and the method is environmentally friendly, simple and convenient to operate and suitable for industrial synthesis of the high-value enamine compounds.
Owner:SHANGHAI INST OF TECH

Method for catalytically synthesizing N-arylated derivative of pyrimidine-2-amine

The invention relates to a method for catalytically synthesizing an N-arylated derivative of pyrimidine-2-amine, which comprises the following steps: by taking an N, N-coordinated meta-carborane ligand-containing cuprous complex as a catalyst and taking pyrimidine-2-amine compounds and aryl halide compounds as raw materials, carrying out coupling reaction at room temperature to obtain the N-arylated derivative of pyrimidine-2-amine. The N-arylation derivative of the pyrimidine-2-amine is obtained. Compared with the prior art, the preparation method disclosed by the invention has the advantages that the N, N-coordinated cuprous complex containing the meta-carborane ligand is used as the catalyst, has higher catalytic activity under a mild condition, can be used for catalyzing Buchwald-Harwig coupling reaction of the pyrimidine-2-amine compound and the aryl halide compound to prepare the N-arylated derivative of pyrimidine-2-amine, is good in universality, and can be used for preparing the N-arylated derivative of pyrimidine-2-amine. The method has the advantages of mild reaction conditions, high catalytic efficiency, few byproducts, lower cost and easiness in separation of products.
Owner:SHANGHAI INST OF TECH

Application of a dinuclear rhodium complex in n-methylation reaction of aliphatic amines

The present invention relates to the application of a kind of binuclear rhodium complex in fatty amine N-methylation reaction, with binuclear rhodium complex as catalyst, with CH 3 I, as a methylating agent, catalyzes the N-methylation reaction of fatty amines in an organic solvent to prepare N-methylated derivatives of fatty amines. Compared with the prior art, the binuclear rhodium complex in the present invention has higher catalytic activity at room temperature, and can be used to catalyze the N-methylation reaction of fatty amines to prepare N-methylated derivatives of fatty amines, and the catalytic reaction The yield is high (90‑97%), the reaction conditions are mild, no strong base is required, all reagents are stable to air and water, the requirements for reaction equipment are not high, and there is a wide range of industrial application prospects.
Owner:SHANGHAI INST OF TECH
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