78results about How to "The synthesis method is scientific and reasonable" patented technology

The invention discloses fluoro-siloxane resin, a preparation method thereof and application thereof as an artificial stone antifouling agent. The fluoro-siloxane resin, the preparation method and the application have the benefits that vinyl silicone, 2-(perfluorinated butyl) ethyl methyl acrylic ester and the like are adopted to prepare a series of fluoro-siloxane resin; the synthesis method is scientific and reasonable, so that a universal method for synthesizing a series of fluoro-siloxane resin is provided, and the preparation method is easy to get raw materials, wide in application range, high in yield and simple and feasible in industrial production operation.

The invention discloses a preparation method of isoxazoloisoquinolinone derivatives under electrocatalysis, which belongs to the technical field of organic synthesis. The method is as follows: into the reactor, add substituted N-alkoxybenzamides and tetra-n-butylammonium hexafluorophosphate with a molar ratio of 1:1, add 95% ethanol as a solvent, and use an electrocatalytic strategy to promote the reaction. After the reaction was completed, the crude product was obtained by concentrating with a rotary evaporator, and then separated by silica gel column chromatography to obtain the target product. The synthesis method of the multi-substituted isoxazoloisoquinolinone derivative provided by the invention is scientific and reasonable, and the synthesis route is green and environment-friendly without metal catalyst; the reaction solvent is 95% ethanol instead of the toxic solvent; the substrate is ready to use under weak current It can be reacted; the synthesis method is simple, the reaction is fast; the yield of the target compound is high, and the product is easy to purify. Its reaction equation is as follows:

The invention discloses a preparation method of a 6-phosphoryl substituted phenanthridine derivative, and belongs to the technical field of organic synthesis. The method comprises the steps that biphenyl isothiocyanate and diaryl oxygen and phosphorus are added into a reactor, by being catalyzed by manganese, heating is conducted in a solvent, after a reaction is completed, cooling is conducted to reach room temperature, a system is diluted with ethyl acetate and washed with saturated sodium chloride, an organic phase is combined, a filtrate is concentrated through a rotary evaporator, a coarse product is obtained, and finally a product is obtained through column chromatography separation. The synthetic method is easy to implement, raw materials are easy to prepare, multiple substituent groups are introduced simultaneously, the product is easy to purify and separate, the yield is high, and the method is suitable for synthesizing the 6-phosphoryl substituted phenanthridine derivative. The reaction equation of the derivative is defined in the description.

The invention discloses a preparation method of a novel poly-substituted diphenylethylene indole derivative and belongs to the technical field of organic synthesis. The method comprises the followingsteps: adding substituted N-methoxy indole formamide, diphenyl acetylene, dichloro-bi(4-methyl isopropyl phenyl)ruthenium (II) and sodium acetate into a reactor. After the stirring and the reacting are finished in a solvent, a rotary evaporator is used for concentrating a filtrate to obtain a crude product, and the crude product is separated through silica gel column chromatography to obtain a target compound. The provided synthesis method of the poly-substituted diphenylethylene indole derivative has the characteristics that the synthesis method is scientific, reasonable and simple, the yieldof the target compound is high, the product is easy to purify, the reaction time is relatively short, the reaction condition is room-temperature aqueous phase, and the synthesis method is environmentally friendly. The reaction equation is as shown in the specification.

The invention discloses a silolene compound shown in formula I, and discloses a method for preparing the silolene compound and application of the silolene compound in serving as a luminescent material.

The invention discloses a preparation method of a 2-alkylsulfenylquinoline derivative. The method comprises the following steps of sequentially adding a compound as shown in the formula II, a compound as shown in the formula III and trifluoromethanesulfonie ester into a reaction vessel, then, adding a solvent, uniformly mixing the solution, and carrying out continuous electrophilic reaction to obtain the 2-alkylsulfenylquinoline derivative as shown in the formula I. The method is scientific and reasonable and capable of synthesizing the 2-alkylsulfenylquinoline derivative which can not be synthesized by using other methods; moreover, the preparation method also has the characteristics of high synthesis yield, good selectivity, easy product purification, no any metal introduction in the synthesis process and the like.

The invention discloses silca bridged cycloalkene compounds of formula (I) and discloses a preparation method of the silca bridged cycloalkene compounds and the use of the silca bridged cycloalkene compounds as luminescent materials.