The invention discloses an injectable
decellularized scaffold for
cartilage repair as well as a preparation method and application of the injectable
decellularized scaffold, and relates to the technical field of medical materials. According to the method, a double-injection mode is adopted, and the gelated gradient injectable
decellularized scaffold is obtained by injecting a pre-gel solution and a
viscosity modifier simultaneously. The decellularized
scaffold can load MSCs to be implanted into a body, is hydrolyzed under a physiological pH value, and slowly releases a
medicine at an injured part, so that the differentiation of the loaded MSCs to
cartilage cells is promoted, and the injured
cartilage tissue is repaired; Due to the gradient property, original biological characteristics of the cartilage tissue can be better simulated, and a better repairing effect is achieved. According to the decellularized
scaffold and the technology, the raw materials are cheap and wide in source, after clinical popularization, the pain of a patient can be remarkably relieved, the operation frequency is reduced, the
treatment effect is improved, and remarkable social and
economic benefits are achieved.