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60results about How to "Reduce the number of surgeries" patented technology

Surgical Tool

ActiveUS20080172052A1Facilitate tissue cauterizationEliminates, the bleedingDiagnosticsSurgical instruments for heatingClinical psychologyRadio frequency
The invention is concerned with cauterizing and resecting tissue. A pair of electrodes are placed on opposed tissue surfaces, and radio frequency power is applied through the electrodes to cauterizing a tissue mass therebetween. After cauterization has been effected, the tissue may be resected along a plane within the cauterized region with minimum or no bleeding. The tissue mass may then be removed.
Owner:AESCULAP AG

Micro-incision iol and positioning of the iol in the eye

An intraocular lens that is capable of being inserted through a micro-incision includes an optic having an anterior and a posterior surface and a plurality of projections extending from the anterior and posterior surfaces. The anterior and posterior surfaces include a recess. The optic is implanted such that a rim of the capsulorhexis is disposed in the recess such that the plurality of projections grip the capsular bag.
Owner:AMO GRONINGEN

Tplo bone plate

A bone plate is dimensioned for securing the rotated cut segment of an upper tibia to the lower portion of the tibia as part of a tibial leveling osteotomy procedure for an animal. The bone plate includes an elongated shaft, a head portion pre-bent with respect to the elongated shaft, and a transition between the elongated shaft and head portion including opposing concave sidewalls. The elongated shaft has a centerline and the pre-bent head portion has a centerline angled with respect to the centerline of the elongated shaft to dispose the elongated shaft collinear or approximately collinear with respect to the lower portion of the tibia and to better fit the head portion to the rotated cut segment of the upper tibia.
Owner:MWI VETERINARY SUPPLY

Artificial dental abutment, artificial dental multi-part implanting system and implanting method

The invention provides an artificial dental abutment, an artificial dental multi-part implanting system and an implanting method. A crown connection section and an implant connection section are respectively arranged at two ends of the artificial dent abutment, wherein the included angle of the axis of the crown connection section and the axis of the implant connection section is 10-30 degrees. The artificial dental abutment can adapt to various oral implanting conditions and angles. An artificially implanted tooth has a harmonious and beautiful repairing effect with surrounding tissues and remained dentition by adopting the abutment. The invention discloses an artificial dental multi-part implanting system comprising the artificial dental abutment, wherein the implant is a multi-part and nonsubmerged technology combined implant, is high in stability and strength, and can adapt to various oral implanting conditions and angles, can be used for effectively reducing the local stress, shortening the healing time and reducing the hurt of patients.
Owner:DALIAN SANSHENG SCI & TECH DEV

System and method for forming a curved tunnel in bone

A drill system for forming a curved tunnel in a bone includes a drill bit guidance device. The drill bit guidance device includes an elongated stationary outer tube extending along a first axis and an elongated inner tube. The elongated inner tube is configured to slidably move within the elongated stationary outer tube along the first axis and to exit from a distal end of the elongated outer tube. The elongated inner tube has a partially slotted distal end portion including a plurality of semi-cross-sectional slots extending perpendicular to the first axis. Each slot is configured to collapse inward in the slot direction when exiting the distal end of the elongated outer tube, thereby curving the distal end portion of the elongated inner tube.
Owner:ASPEN SURGICAL PRODUCTS INC

System and method for forming a curved tunnel in bone

A drill system for forming a curved tunnel in a bone includes a drill bit guidance device. The drill bit guidance device includes an elongated stationary outer tube extending along a first axis and an elongated inner tube. The elongated inner tube is configured to slidably move within the elongated stationary outer tube along the first axis and to exit from a distal end of the elongated outer tube. The elongated inner tube has a partially slotted distal end portion including a plurality of semi-cross-sectional slots extending perpendicular to the first axis. Each slot is configured to collapse inward in the slot direction when exiting the distal end of the elongated outer tube, thereby curving the distal end portion of the elongated inner tube.
Owner:SPECIALTY SURGICAL INSTR INC

Easily-removing implant device and screwing-out tool thereof

InactiveCN103550003AReduce the risk of absorbingAvoid secondary surgeryDental implantsNeck partsImplanted device
The invention discloses an easily-removing implant device and a screwing-out tool thereof. The easily-removing implant device comprises an implant, a base station and a central bolt; the easily-removing implant device is characterized in that the implant comprises a gum-penetrating neck part and a head part, wherein a thread is formed on the outer surface of the head part, at least two spiral self-tapping grooves are also formed in the outer surface of the head part, a connecting hole coaxial with the implant is formed in the implant, the connecting hole comprises a tapered hole, an anti-rotation hole, an implant taking-out section and a blind threaded hole, which are sequentially connected coaxially, the base station comprises a dental crown connecting section and an implant connecting section, the implant connecting section comprises a conical table and an anti-rotation column, a stepped hole matched with the central bolt is formed in the base station, and the central bolt penetrates through the stepped hole to be connected with the blind threaded hole, so that the base station and the implant are fixed integrally. According to the easily-removing implant device, the implant taking-out section with a reverse thread is additionally arranged in the implant, the problem that a part of the implant, which is remained in dentale due to fracture of the implant, is difficult to take out is solved, and the easily-removing implant device has the advantages of simple structure, strong practicability, and the like.
Owner:DALIAN SANSHENG SCI & TECH DEV

Diagnosis of melanoma by nucleic acid analysis

The present invention provides methods for diagnosing melanoma and / or solar lentigo in a subject by analyzing nucleic acid molecules obtained from the subject. The present invention also provides methods for distinguishing melanoma from solar lentigo and / or dysplastic nevi and / or normal pigmented skin. The methods include analyzing expression or mutations in epidermal samples, of one or more skin markers. The methods can include the use of a microarray to analyze gene or protein profiles from a sample.
Owner:DERMTECH INT

Parallel external fixator and application method thereof

The invention discloses a parallel external fixator and an application method thereof, and relates to bone treating devices or methods. The external fixator comprises a frame part and a matching computer software part, wherein the frame part is composed of a reference ring, a shift ring and six drive rod. The application method comprises the steps that the parallel external fixator is installed; standard frontal and lateral X-ray photographs are shot; a local coordinate system of the parallel external fixator and a global coordinate system of the parallel external fixator are built; malformation parameters and installation parameters are acquired by measurement; the lengths of the six drive rods of the parallel external fixator is obtained; precise fracture reduction is achieved through treatment days given by a doctor. The parallel external fixator and the application method thereof overcome the defect in the prior art that good extremities abutting needs multiple repeated reduction which can increase the risk of secondary damages to soft tissues and nerves and blood vessels.
Owner:SHANGHAI LAIYING MEDICAL TECH CO LTD

System and method for forming a curved tunnel in bone

InactiveUS20150141998A1Reduce risk of infectionReduce surgical proceduresSuture equipmentsBiomedical engineeringDrill bit
A drill system for forming a curved tunnel in a bone includes a drill bit guidance device. The drill bit guidance device includes an elongated stationary outer tube extending along a first axis and an elongated inner tube assembly. The elongated inner tube assembly is configured to slidably move within the elongated stationary outer tube along the first axis and to exit from a distal end of the elongated outer tube. The elongated inner tube assembly includes an actuating tube and an actuator tube. The actuating tube slidably moves within the actuator tube and includes a plurality of semi-cross-sectional slots extending in a slot direction perpendicular to the first axis. Each slot of the actuating tube is configured to collapse inward in the slot direction when exiting the distal end of the elongated outer tube, thereby causing a distal end portion of the elongated inner tube assembly to follow a curved path.
Owner:SPECIALTY SURGICAL INSTR INC

Source/seed delivery surgical staple device for delivering local source/seed direclty to a staple margin

A source delivery surgical staple device delivers a source / seed to a staple margin. The surgical staple delivery device includes a main staple body segment hingedly attached to a second body segment. Each of the segments is appointed for engagement to dispense the sources / seeds and / or a surgical staple to the staple margin. The device also includes a cartridge removably attached and snapped onto the main staple body segment. The cartridge has at least one staple line appointed for housing surgical staples, and being operative to form at least one staple line of surgical staples, and at least one cut line. The cartridge also has at least one source / seed / brachy staple line forming a brachy or radioactive seeds and / or chemotherapy agent dosage source. The radioactive seeds have a radioactive and / or chemotherapy source supported by leg portions that are manipulated during insert for fastening the radioactive staples to tissue at an incision margin. With this arrangement, a hybrid of chemotherapy agent and radiation is delivered directly into the staple lines and different dosage brachy loads can be loaded in the cartridge.
Owner:SHARIATI NAZLY MAKOUI

Injectable decellularized scaffold for cartilage repair as well as preparation method and application of injectable decellularized scaffold

ActiveCN112807489ASolve the problem of repairing irregular cartilage damagePromote degradationTissue regenerationProsthesisCartilage cellsAcellular scaffold
The invention discloses an injectable decellularized scaffold for cartilage repair as well as a preparation method and application of the injectable decellularized scaffold, and relates to the technical field of medical materials. According to the method, a double-injection mode is adopted, and the gelated gradient injectable decellularized scaffold is obtained by injecting a pre-gel solution and a viscosity modifier simultaneously. The decellularized scaffold can load MSCs to be implanted into a body, is hydrolyzed under a physiological pH value, and slowly releases a medicine at an injured part, so that the differentiation of the loaded MSCs to cartilage cells is promoted, and the injured cartilage tissue is repaired; Due to the gradient property, original biological characteristics of the cartilage tissue can be better simulated, and a better repairing effect is achieved. According to the decellularized scaffold and the technology, the raw materials are cheap and wide in source, after clinical popularization, the pain of a patient can be remarkably relieved, the operation frequency is reduced, the treatment effect is improved, and remarkable social and economic benefits are achieved.
Owner:GUANGDONG GENERAL HOSPITAL

Source/seed delivery surgical staple device for delivering local source/seed direclty to a staple margin

A source delivery surgical staple device delivers a source / seed to a staple margin. The surgical staple delivery device includes a main staple body segment hingedly attached to a second body segment. Each of the segments is appointed for engagement to dispense the sources / seeds and / or a surgical staple to the staple margin. The device also includes a cartridge removably attached and snapped onto the main staple body segment. The cartridge has at least one staple line appointed for housing surgical staples, and being operative to form at least one staple line of surgical staples, and at least one cut line. The cartridge also has at least one source / seed / brachy staple line forming a brachy or radioactive seeds and / or chemotherapy agent dosage source. The radioactive seeds have a radioactive and / or chemotherapy source supported by leg portions that are manipulated during insert for fastening the radioactive staples to tissue at an incision margin. With this arrangement, a hybrid of chemotherapy agent and radiation is delivered directly into the staple lines and different dosage brachy loads can be loaded in the cartridge.
Owner:SHARIATI NAZLY MAKOUI

Combined-type soft tissue horizontal dental implant

The invention discloses a combined-type soft tissue horizontal dental implant which comprises a base of the dental implant, an implant root and a fixing screw which connects the base with the implant root. An outer thread is arranged at the implant root, and the surfaces of dental sides of one or more sides of the outer thread are rough surfaces. By means of the combined-type soft tissue horizontal dental implant, 'synostosis' between the dental implant root and the surrounding bone tissue is more facilitated, and meanwhile the phenomenon of spin of the implant under the action of external force can be hindered.
Owner:吴大怡

CT guide multi-functional navigation puncture treating template

The invention relates to a multi-functional navigation puncture treating template. The multi-functional navigation puncture treating template comprises a template body, puncture main needle holes, puncture subsidiary needle holes, marking lines and lead numbers, puncture needle holes with different sizes distributed in rows and in columns are evenly arranged on the template body, the lead numbers are placed at the positions, corresponding to left side needle holes, of row marking lines as row marks, and lead threads are placed at the positions, corresponding to the upper portion of the needle holes, of column marking lines as column marking lines. The multi-functional navigation puncture treating template can fast determine the positions of the needle holes, precisely guide the puncturing direction of a puncture needle, the puncture needle is precisely inserted, the operation time is shortened, the operation risk is lowered, and the operation difficulty is reduced. Different puncture holes can simultaneously combines a puncture biopsy with various kinds of minimally invasive treatment, the puncture biopsy is conducted at the same time of the treatment, and the pain of a patient is lowered; various kinds of the minimally invasive treatment can also be combined, all own advantages are given play to, the disadvantages of various kinds of the minimally invasive treatment are avoided, the maximum tumor treating effect is achieved, and the combined operation not only relieves the burden on the patient, but also improves the curative effect of tumor treatment.
Owner:于江平

Method for preparing matrix-induced autologous bone mesenchymal stem cell composite scaffold

The invention discloses a method for preparing a matrix-induced autologous bone mesenchymal stem cell composite scaffold. The method specifically comprises the steps of preparing bone marrow suspension; taking peripheral blood of a patient and putting the peripheral blood of the patient in a blood bag; preparing autoserum; obtaining target cells; adding 15 ml DMEM high glucose culture medium to the target cells, inoculating a T25 cell culture bottle with the target cells, and placing the T25 cell culture bottle in an incubator for culture; rinsing the cells twice with PBS solution; adding the DMEM high glucose culture medium into the culture bottle dropwise to stop digestion; obtaining cleaned sediment; inoculating the cell culture bottle with the cells for continuous culture; conducting passage three times; adding trypsin-EDTA solution into the culture bottle; washing the cells three times with PBS; conducting cell resuspension; placing a sterile pig source I / III type collagen membrane in a sterile plastic culture dish, and soaking the membrane in the DMEM high glucose culture medium for one night; and dropping cell suspension onto the pig source I / III type collagen membrane, and conducting culture for 3 days. The method has the advantages of being high in treatment precision and the like.
Owner:安徽安龙基因科技有限公司

Medical equipment for congenital esophageal atresia and preparation method thereof

The invention discloses medical equipment for congenital esophageal atresia and a preparation method thereof. The equipment includes an upper section guide device, a lower section guide device and a digital Gauss meter. The upper section guide device comprises a first upper section hose and an upper section magnetic attraction device arranged at the lower end of the first upper section hose, the upper section guide device comprises a first lower section hose and a lower section magnetic attraction device arranged at the upper end of the first lower section hose. The invention also discloses the preparation method of the medical equipment for congenital esophageal atresia. According to the invention, the upper blind end and the lower blind end of the esophagus can synchronously grow, self-healing and running through are achieved, the structure and the functional integrity of the esophageal of a child patient are preserved, the operation mode of replacing the esophagus by the other device tubes is avoided, and the upper blind end and the lower blind end esophagus are automatically matched and communicated through the magnetic action, with the aid of the digital Gauss meter, the growth condition of the esophagus growth is observed, the number of operations is reduced, and the wound caused by the operation treatment is reduced to a great extent.
Owner:广州星顿医疗科技有限公司

Anti-infection internal fixation apparatus for long bones of limbs

An anti-infection internal fixation apparatus for long bones of limbs, belonging to the technical field of orthopedic medical devices, is used for fighting infections during internal fixation. The technical scheme comprises: a board of a bone plate and the surface of a nail body of an intramedullary nail are provided with several grooves or circular bulges filled up with medicine; the grooves are arranged in parallel in the longitudinal direction of the bone plate board and of the intramedullary nail body. Or the circular bulges are evenly distributed on the bone plate board and the surface of the intramedullary nail body. Medicine is added in the grooves or between the circular bulges. The grooves or the circular bulges can be filled up with slow-release sensitive antibiotics so that the medicine can be delivered directly to the lesion. The targeted control of infection increases the replacement success rate of internal fixation, improves therapeutic effect, and reduces pains and financial burden for patients. The provided anti-infection internal fixation apparatus for long bones of limbs is an innovation in the technical field of orthopedic medical device, effectively overcoming the defect that the internal fixture works as one of sources of infection, giving solution to a long term unsolved problem, greatly decreasing the number of operation and time of recovery, and having great application value.
Owner:陈卫 +1

Children type tumor joint prosthesis reserving femur neck and knee joint surface

InactiveCN111789702APreserve bone growth functionImprove stabilityJoint implantsFemoral headsEngineeringFEMORAL CONDYLE
The invention provides a children type tumor joint prosthesis reserving a femur neck and a knee joint surface. The children type tumor joint prosthesis reserving a femur neck and a knee joint surfacecomprises a backbone extension segment, wherein a femur near end prosthesis and a femur far end prosthesis are respectively assembled and connected to two ends of the backbone extension segment; porous structure grooves having bone trabecula are formed in the junction surface of the femur near end prosthesis and a femur and the junction surface of the femur far end prosthesis and femur condyle; afemur outside steel plate is in dismountable connection to the outer side of the femur far end prosthesis; and a femur near end central pulling force nail and femur near end assistant nail are connected with the femur near end prosthesis and the femur, and locking nails and spongy bone pulling force nails are connected with the femur far end prosthesis and the femur condyle. The prosthesis is connected with metaphyseal dysplasia tissue of a femur upper segment and a femur far end, and the bone growth function of a child patient is reserved. The situation that the skeleton growth of a postoperative child patient is not limited by the steel plate can be guaranteed, after the prosthesis and bone tissue form reliable biological fixation, the femur outside steel plate can be demounted, and theincreased spongy bone pulling force nails crossed inside and outside can further improve the stability and the reliability of the prosthesis.
Owner:BEIJING LIDAKANG TECH

TPLO bone plate

A bone plate is dimensioned for securing the rotated cut segment of an upper tibia to the lower portion of the tibia as part of a tibial leveling osteotomy procedure for an animal. The bone plate includes an elongated shaft, a head portion pre-bent with respect to the elongated shaft, and a transition between the elongated shaft and head portion including opposing concave sidewalls. The elongated shaft has a centerline and the pre-bent head portion has a centerline angled with respect to the centerline of the elongated shaft to dispose the elongated shaft collinear or approximately collinear with respect to the lower portion of the tibia and to better fit the head portion to the rotated cut segment of the upper tibia.
Owner:MWI VETERINARY SUPPLY

Human body induction wireless charging device

The invention provides a human body induction wireless charging device which comprises an induction part, a power supply network part and an application part. The induction part comprises a heat energy converter and / or a human body current receiving device which are / is in contact with a human body, and transmits the electric energy to the power supply network part through a coupling resonance typetransmission coil; the power supply network part charges a rechargeable battery and transmits the electric energy to the application part through the coupling resonance type transmission coil; and the application part comprises an application element and is used for using the electric energy. The device can be charged wirelessly and continuously by using the electric energy and heat energy generated by the human body, and has the good sustainability and environmental friendliness.
Owner:TIANJIN POLYTECHNIC UNIV

Method for automatically extracting feature points of digital model of preoperative nasal-alveolar process appliance

The invention discloses a method for automatically extracting feature points of a digital model of a preoperative nasal-alveolar process appliance. The method comprises the following steps: S1, acquiring an oral impression model file and preprocessing the oral impression model file; S2, performing coordinate system transformation on the preprocessed oral impression model; S3, performing segmentation processing on the oral impression model after coordinate system transformation; S4, performing two-dimensional plane projection on digital models of the alveolar bones on the two sides, and performing image fitting on the projected images of the alveolar bones on the two sides to obtain a fitting graph; and S5, performing side plane projection on the alveolar bones of the healthy side and the affected side according to the fitting graph, segmenting a ridge line according to the side plane projection, and extracting feature point coordinates according to the trend of the ridge line. Dimension reduction processing is performed on three-dimensional digital model data, and feature points are extracted by using image fitting and feature recognition technologies; the method can provide guidance for the design of a preoperative cleft lip and palate correction model, reduces the operation risk, improves the correction success rate, and has good commercial prospect and values.
Owner:WUHAN UNIV

Bone plane root-form dental implant

The invention discloses a bone plane root-form dental implant which comprises a dental implant abutment, an implant abutment jack, an implant root and an implant abutment central fixing screw. External threads are arranged at the implant root, a truncated cone is arranged on a lower section of the implant root, a small end of the truncated cone is arranged on the lower side, a threaded surface is arranged on an upper section of a cone surface of the truncated cone, a smooth surface is arranged on a lower section of the cone surface of the truncated cone, rough surfaces are arranged on dental-side surfaces of two edges of the external threads, and rough surfaces are arranged on dental-side surfaces of two edges of threads on the upper section of the cone surface of the truncated cone. The bone plane root-form dental implant has the advantages that the bone plane root-form dental implant is favorable for promoting tissue healing after the dental implant root is implanted in a patient and is particularly favorable for regeneration and bonding of peripheral bone tissues which are flush with interface planes of the implant root abutment; the bone plane root-form dental implant is favorable for early implementing states of 'synosteosis' between the implant root and the tissues; the bone plane root-form dental implant is favorable for acquiring excellent initial retention states, and spinning of the implant under the effect of external force can be prevented; the implant root and the upper abutment can be precisely matched with each other, and accordingly poor conditions such as micro-leakage of interfaces and rotation of the abutment can be prevented.
Owner:吴大怡

Isolation perfusion part, ablation electrode tip and tumor radiofrequency ablation treatment device

An isolation perfusion member, an ablation electrode tip and a tumor radiofrequency ablation treatment device, the isolation perfusion member comprises an arc baffle, an extrusion airbag, a flexible substrate and a plurality of perfusion puncture heads, and the radiofrequency ablation electrode tip comprises an electrode needle, an outer sleeve and an isolation perfusion assembly or (the isolation perfusion assembly and a puncture perfusion member); the tumor radiofrequency ablation treatment device comprises a host, an image system, an auxiliary electrode, a radiofrequency ablation electrode tip, a normal saline pumping system and an air supply system. According to the radiofrequency ablation electrode tip, normal saline can be evenly poured into tumor tissue in the treatment process, on one hand, the ion content of the tumor tissue can be increased, then ablation energy is improved, the size of an ablation focus is increased, and the treatment effect is improved, on the other hand, the form of a solidification area of the tumor tissue is more regular and controllable, therefore, tumor residues and thermal damage to important anatomical structures adjacent to the target site are avoided.
Owner:洛阳嘉泽医疗科技有限公司

Elastic expansion spine growth rod system

The invention discloses an elastic expansion spine growth rod system. The system comprises an orthopedic rod, a clip, a spring and a spring sleeve; the orthopedic rod is a round rod, the clip comprises a snap ring and a locking screw, the snap ring sleeves the orthopedic rod, the snap ring is provided with a screw hole, and the locking screw runs through the screw hole to be in locked connection with the orthopedic rod; the spring sleeves the orthopedic rod between the end of the orthopedic rod and the clip, and the spring is sleeved with the spring sleeve; the spring sleeve is a square tube.The elastic expansion spine growth rod system can not only prevent scoliosis from being aggravated, but also can continuously exert an expansion effect along with the growth of the spine of a child patient, the structure is simple, the use is convenient, the manufacturing cost is low, the operation frequency is greatly reduced, the bending expansion force is larger, and the corrective effect on patients with large curvature of the scoliosis is better.
Owner:PEKING UNION MEDICAL COLLEGE HOSPITAL CHINESE ACAD OF MEDICAL SCI

Injectable hyaluronic acid hydrogel for cartilage repair and preparation method of injectable hyaluronic acid hydrogel

The invention relates to a medical material, in particular relates to the field of cartilage damage regeneration and mainly discloses an injectable hyaluronic acid hydrogel for cartilage repair and apreparation method of the injectable hyaluronic acid hydrogel. The hyaluronic acid hydrogel product provided by the invention mainly aims at cases that cartilage defect shapes are irregular and conventional regenerated cartilage is not well combined with host cartilage, can be injected, can be spontaneously formed as a gel in a liquid environment, is good in adhesiveness, and achieves seamless combination of cartilage defect parts and filling materials.
Owner:GUANGDONG GENERAL HOSPITAL

Autologous fat transplantation device capable of increasing fat cell survival rate

The invention discloses an autologous fat transplantation device capable of increasing the fat cell survival rate. Multiple liposuction cavities and injection cavities are utilized for liposuction and injection steps, the positions of liposuction and fat injection in the human body are dispersed, and the problem of cutis laxa caused by over-concentrated liposuction position and the problem of low fat cell survival rate caused by over-concentrated fat injection position are prevented; the liposuction cavities and injection cavities are formed in a support by means of sliding blocks and sliding rails, needles of all liposuction cavities and injection cavities can be controlled to be in different working planes through limiting devices, and therefore the device conforms to the structure of the liposuction or injection part of the human body; in addition, fat cells and adipose-derived stem cells are separated from fat tissue which is taken out by means of a processing device, cultured respectively and then co-cultured, the adipose-derived stem cells are induced to be differentiated into capillaries in the fat cells, the survival rate of the fat cells is increased, and then the frequency of surgery is reduced.
Owner:北京欧扬医疗美容门诊部有限公司

Preparation method for collagen membrane inoculated with autologous mesenchymal stem cells

The invention discloses a preparation method for a collagen membrane inoculated with autologous mesenchymal stem cells. The preparation method comprises the following concrete steps: carrying out uniform mixing so as to obtain a marrow suspension; preparing autologous serum; adding the marrow suspension into a centrifuge tube containing a cell separating medium and carrying out gradient centrifugation to obtain a sediment which is target cells; adding the target cells into 15 ml of a DMEM high-glucose medium containing FGF-2, the autologous serum and gentamycin, carrying out culturing in an incubator and replacing the DMEM high-glucose medium once every three days; after cell culture for 3 to 4 weeks, carrying out passage three times; subjecting cells to resuspension with normal saline; slowly adding the cell suspension onto the rough surface of a prepared pig-sourced I / III type collagen membrane with a plastic sleeve drop by drop; and allowing the collagen membrane to adsorb cells for 10 to 15 min so as to obtain the collagen membrane inoculated with the autologous mesenchymal stem cells. The collagen membrane inoculated with autologous mesenchymal stem cells prepared in the invention has the advantages of good treatment effect, convenience in treatment, low cost, etc.
Owner:安徽安龙基因科技有限公司
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