267results about How to "Reduce dead volume" patented technology

The invention describes features that can be used to control flow to an array of microchannels. The invention also describes methods in which a process stream is distributed to plural microchannels.

Microfluidics packages and methods of use are described, comprising in one embodiment a substrate having a top surface and means to lower pressure on the top surface; a fluidics card having a bottom surface and means to allow fluids to traverse through the card; and a polymeric barrier film, the polymeric barrier film positioned between the top surface of the substrate and the bottom surface of the fluidics card.

The present invention relates to a fluid sample transport device (1) with reduced dead volume for processing, controlling and / or detecting a fluid sample (3), comprising: a substrate (2), wherein the upper surface of said substrate (2) comprises at least one processing, controlling and / or detecting element (19); at least one flexible membrane (4), wherein the flexible membrane (5) is arranged on the upper surface of said substrate (2); at least one plunger (5) and / or actuating element (9) for actuating an up and / or down movement of the flexible membrane (4) to cause a fluid flow and / or to stop a fluid flow; at least one cover plate (6) arranged on the upper outer surface or lower outer surface of the flexible membrane (4), wherein the cover plate (6) comprises at least one through going hole (10) and / or cut-out (10) for receiving a plunger (5) and / or actuating element (9), so that movement of said plunger (5) and / or actuating element (9) causes a pump and / or valve action of the adjacent arranged flexible membrane area to cause a fluid flow between the upper surface of said substrate (2) and the lower surface of said flexible membrane (4); and wherein at least one channel (7) to direct the fluid sample (3) flow on the substrate (2) is temporally formed by the flexible membrane.

A fluid dispenser comprising a fluid reservoir of variable working volume, at least one deformable wall defining an inside surface, and a dispenser orifice through which the fluid is dispensed while the working volume of the reservoir is being reduced by deforming the deformable wall, the dispenser further comprising a piston element that is in leaktight sliding contact with the inside surface of the deformable wall, said piston element comprising an upstream face that is not in contact with the fluid, and a downstream face that is in contact with the fluid and that forms a displaceable wall of the reservoir, said upstream face being separated from said downstream face by a zone that is in leaktight contact with the inside surface.

A device for dispensing a liquid-to-pasty product to be placed at the open end of a rigid container and consisting of a manual metering pump for dispensing a predetermined amount of the product to be dispensed, includes a base member to be placed on the container, a push button provided with a dispensing spout capable of acting, when pumped, against an intermediate bellows comprising an opening / closing device provided at the upper end of the bellows, characterized in that the push button is combined with a cylindrical chamber directed towards the inside of the bellows and extending inside the bellows so as to form a dead volume with a predetermined value inside same and to accordingly reduce the available air volume, thereby improving the compression rate when pumped.

In injecting a sample sucked into a sample loop in an autosampler from an injection needle into an analytical flow path via an injection port by a mobile phase, a sending flow rate of the mobile phase is reduced from a certain flow rate determined in an analysis condition to reduce pressure applied on a joint section between the needle and the injection port to thereby reduce the sample remaining in the injection port.

The invention relates to an LC / MS interface provided with structure that the end of a spray capillary is rarely damaged and the object is to provide the LC / MS interface which a general user can easily operate, which inhibits the extension of a separation band and the deterioration of detection sensitivity and which enables high separation and sensitive analysis. A metallic member having a hole for connecting a separation column and a spray capillary and a resin member for fixing the upstream side of the short spray capillary are used. Further, to enhance operability, spray ionization using gas spraying is used.

The invention relates to a disposable breast cup set which comprises a coupling element (2) to be coupled to a milk collection receptacle (1) and a breast cup connecting element (3) to be coupled to a breast cup funnel (5). The coupling element (5) and the breast cup connecting element (3) are interlinked via a tamper-evident element (4), said connection being destroyed when the coupling element (2) is for the first time separated from the breast cup connecting element (3) and preventing re-use of the set.