The invention discloses a flue gas traversing type high-pressure spraying dust remover, which comprises a high-pressure spraying chamber, a water storage tank, a circulating water flowing tank, an inlet smoke passing chamber and an outlet smoke passing chamber, the high-pressure spraying chamber is of a funnel-shaped cavity structure composed of a porous side plate and a shell outer plate, an L-shaped water receiving plate is arranged on the inner side surface of the porous side plate, and smoke passing holes are formed in a vertical plate section; the multiple stages of L-shaped water receiving plates form a step structure, and a spraying pipe is arranged at the top of the high-pressure spraying chamber; activated carbon filler and a top plate water outlet are arranged at the bottom of the reservoir; the inlet smoke passing chamber is provided with a first porous partition plate, a smoke inlet pipe connector and a first baffle plate. The outlet smoke passing chamber is provided with asecond porous partition plate, a smoke outlet pipe connector and a second baffle plate. By means of the perforated plate smoke guide structure and reasonable structural design and space layout, smokeis sequentially subjected to the water-gas fusion process of high-pressure spraying, water curtain traversing and water mist, the fusion process is reasonable and orderly, the contact area and fusiondegree of water fluid and the smoke are increased, and the desulfurization and dust removal effects are improved.