55results about How to "Loss of elasticity" patented technology

The invention relates to a cosmetic or dermatological composition containing a carrier comprising at least one fatty phase characterized in that it contains at least one derivative or a mixture of derivatives of 1,7-diphenyl-3,5-heptanedione having a particular structure and at least one oil having, in its structure, at least one amide unit.The invention also relates to its uses in cosmetics and dermatology, in particular for preventing or combating the harmful effects of UV radiation and pollution on human keratinous materials, and more particularly for preventing and / or treating photoaging of the skin.The invention also relates to a method for solubilizing a derivative or a mixture of derivatives of 1,7-diphenyl-3,5-heptanedione having a particular structure with at least one oil having, in its structure, at least one amide unit.

The invention provides compositions for stimulating the formation of one or more extracellular matrix components that contain a lipoaminoacid derivative of the tripeptide carnosine such as N-Octanoyl Carnosine. Also provided are compositions containing N-Octanoyl Carnosine in combination with selected tripeptide and / or tetrapeptides as well as pharmaceutical and / or cosmetic compositions containing such compositions. The invention further provides methods of using the compositions and compositions of the invention to treat, alleviate, and / or ameliorate a symptom, condition, disorder, or disease of the skin or mucosa, wherein the symptom, condition, disorder, or disease is associated with changes in extracellular matrix components.

Personalized skin-specific topical formulations containing conditioned medium obtained from cultures of fibroblasts has been developed. Unlike other topical formulations, these formulations are specific for the recipient-skin type specific, and conditioned medium is obtained from a subject with desired skin characteristics. For example, since African American skin is known to wrinkle less and later than Caucasian skin, conditioned medium may be obtained from African American skin for application to pale skin. In another embodiment, the fibroblasts are obtained from young skin for administration to older skin. In still another embodiment, the fibroblasts are obtained from skin that does not suffer from acne or discoloration, for application to skin that is prone to acne or discoloration. Examples of skin donor selection criteria include delayed wrinkling, small pores, resistance to sunburn, resistance to acne, uniform coloration or lack of blotching or age spots and good moisture retention.

Uses of topical compositions comprising a 2-hydroxycarboxylic acid or related compound to alleviate or improve signs of skin, nail and hair changes associated with intrinsic or extrinsic aging are disclosed. 2-Hydroxycarboxylic acids and their related compounds include, for example, 2-hydroxyethanoic acid, hydroxypropanoic acid, 2-methyl 2-hydroxypropanoic acid, 2-phenyl 2-hydroxyethanoic acid, 2-phenyl 2-methyl 2-hydroxyethanoic acid, 2-phenyl 3-hydroxypropanoic acid, 2,2-diphenyl 2-hydroxyethanoic acid, 2-hydroxybutane-1,4-dioic acid, 2,3-hihydroxybutane-1,4-dioic acid, 2-carboxy 2-hydroxypentane-1,5-dioic acid, 2-ketopropanoic acid, methyl 2-ketopropanoate, ethyl 2-ketopropanoate, and gluconolactone. Topical application of compositions comprising 2-hydroxycarboxylic acid and / or related compounds has been found to alleviate or improve skin lines; blotches; blemishes; nodules; wrinkles; pigmented spots; atrophy; precancerous lesions; elastotic changes characterized by leathery, coarse, rough, dry and yellowish skin; and other skin changes associated with intrinsic aging or skin damages caused by extrinsic factors such as sunlight, radiations, air pollution, wind, cold, dampness, heat, chemicals, smoke and cigarette smoking. Topical applications of such compositions have also been found to improve the overall qualities of nail and hair affected by intrinsic aging or damaged by extrinsic factors.

A tool holder having two distinct phases, a first phase in which the tool is held in an interference fit with sufficient mechanical interaction between two for the tool to be rotated at high speed and perform its intended purpose on a workpiece, and a second phase in which the tool is sufficiently released from the interference fit to be rapidly removed from the holder (as by an automated apparatus).

Provided are methods for improving the appearance aging or of peri-menopausal, menopausal, or post-menopausal skin comprising: applying to the skin tissue of a mammal in need of such regulation, a safe and effective amount of a composition comprising at least one Szeto-Schiller peptide and a dermatologically acceptable carrier. Compositions for use in the methods are also provided.

Provided are methods for improving the appearance aging or of peri-menopausal, menopausal, or post-menopausal skin comprising: applying to the skin tissue of a mammal in need of such regulation, a safe and effective amount of a composition comprising at least one Szeto-Schiller peptide and a dermatologically acceptable carrier. Compositions for use in the methods are also provided.

Topical compositions including niacinamide mononucleotide to improve the appearance of aging skin and to prevent and treat skin aging; and methods of use of topical compositions including niacinamide mononucleotide to improve the appearance of aging skin and to prevent and treat skin aging

The invention provides compositions for stimulating the formation of one or more extracellular matrix components that contain a lipoaminoacid derivative of the tripeptide carnosine such as N-Octanoyl Carnosine. Also provided are compositions containing N-Octanoyl Carnosine in combination with selected tripeptide and / or tetrapeptides as well as pharmaceutical and / or cosmetic compositions containing such compositions. The invention further provides methods of using the compositions and compositions of the invention to treat, alleviate, and / or ameliorate a symptom, condition, disorder, or disease of the skin or mucosa, wherein the symptom, condition, disorder, or disease is associated with changes in extracellular matrix components.

The subject of the present invention is a method for characterizing the distribution of the volumes of the surface of the skin of an individual, more particularly applicable in the evaluation of the effect of firming cosmetic products. This method uses the isolines and the gradients of the slopes computed from a three-dimensional representation of the surface of the skin.

The invention discloses a brightening lipstick and a preparation method thereof, which relates to the technical field of cosmetic. The brightening lipstick comprises the following components in partsby weight: 30-36 parts of diisostearyl malate, 12-16 parts of di-diglycerin fatty acid ester, 11-15 parts of beeswax, 6-10 parts of ceresine, 6-10 parts of phytosteryl Isostearate, 9-15 parts of a softener, 1-3 parts of isopropyl palmitate, 0.1-0.2 parts of an anti-oxidant, 0.1-0.5 parts of an antiseptic, and 0.1-0.5 parts of a coloring agent. The brightening lipstick is capable of keeping moisture and locking water, reducing skin dehydration rate, and restoring injured skin of lip, and has the advantages of lasting effect of moisture retention.

The invention discloses a compound essential oil for whitening skin and removing skin wrinkles and relates to cosmetics and a medical appliance, in particular to a compound essential oil for whitening skin and removing skin wrinkles. The compound essential oil comprises the following raw materials in percentage by weight: 30-55 percent of rosemary essential oil, 20-35 percent of tea tree essential oil, 35-55 percent of orange flower essential oil, 25-35 percent of pogostemon cablin essential oil, 25-45 percent of geranium essential oil and 1,000 percent of caper euphorbia seed essential oil. The compound essential oil for whitening skin and removing skin wrinkles of the invention is prepared by adopting the steps of mixing and stirring the raw materials according to the proportion prescription and then standing. The invention can rapidly and thoroughly whitening skin and restore skin elasticity and achieves the effects of whitening skin and removing skin wrinkles.

The invention belongs to the field of pharmaceuticals, health-care foods or foods and particularly relates to a composition having face-beautifying and weight-losing effects and a preparation method and application thereof.The composition is prepared from, by weight, 15-60 parts of dietary fibers, 10-30 parts of arabinose, 1-10 parts of kidney bean protein, 0.1-5 parts of L-carnitine, 1-2 parts of chitosan oligosaccharide, 0.01-20 parts of collagen peptide, 0.01-20 parts of soybean oligopeptide and 0.01-5 parts of a guarana extract.According to the composition having the face-beautifying and weight-losing effects, full consideration is given to the composition of the raw materials and the mutual proportion of the raw materials is selected to make the raw materials mutually and proportionally matched and produce the combined action.The composition has the weight-losing effect, can improve the radiance and elasticity of the skin and prevent the phenomenon that the skin loses the elasticity and collapses due to weight losing while losing the weight, and meanwhile plays the face-beautifying and weight-losing effects.

A Maillard reaction inhibitor which effectively inhibits the progress of a Maillard reaction in a living body, can be safely applied without adverse side effects, can be manufactured without any complicated process, a skin anti-aging agent, an anti-diabetic complication agent and foods and beverages using the same. The Maillard reaction inhibitor contains 50 to 90% by mass of polyphenol as an active ingredient. The Maillard reaction inhibitor has a potent Maillard reaction inhibitory activity in a living body and allows for the prevention and improvement of the various dysfunction of protein in a living body. Due to this activity, the Maillard reaction inhibitor suppresses aging and can prevent and / or treat diabetic complications. Furthermore, when the above-described tannin is mixed in foods and beverages containing collagen, it is possible to suppress the Maillard reaction in the foods and beverages to suppress the deterioration of the foods and beverages.

The present invention relates to a method for inhibiting or reversing non-enzymatic glycation of the first intermediate of a biological moiety using an α-thiolamine. By inhibiting or reversing non-enzymatic glycation of the biological moiety, conditions such as aging and diabetic complications can be prevented or reversed.

Compositions, methods, and processes are used in topical applications for human or animal skin. In a first embodiment, a combination of active ingredients: caffeine, trehalose, asparagus extract, ceramide 2 (2%), and a resurrection plant, Myrothamnus flabellifolia, extract are used in a topical formulation, such as a cream, lotion, spray or gel to boost or activate autophagy, the body's innate processes for repairing cell damage. In a second embodiment, nutrients, selected from essential fatty acids, and phytonutrients are added to the active ingredients of the first embodiment and used in different formulations to provide products for topical application, including, but not limited to, a cleanser, a spray essence, a day cream, a night cream, a serum, a mask, and a booster. The active ingredients provide a unique “autophagy activating nutrient complex,” that improves skin integrity and changes the way skin ages, restores and renews radiance.

The invention concerns a two-component polyurethane composition including a polyol component K1 and a polyisocyanate component K2, the polyol component K1 including castor oil A1 and 1,2,3-propane triol A2, and the polyisocyanate component K2 including at least one aromatic polyisocyanate B1, the ratio in weight percent of (A1 / A2) being between 4 and 50 and the ratio of all NCO groups of the aromatic polyisocyanates B1 to all the OH groups totaling (A1+A2)=1.15:1-85:1, and the total of all the OH groups of (A1+A2) being >93% of the total of all the OH groups of the two-component polyurethane composition, characterized by controllable hydrolytic degradability.

The invention belongs to the technical field of electronic equipment, and particularly relates to an elastic sheet and electronic equipment. The elastic sheet comprises a base and an elastic arm, wherein a first protection part and a second protection part are respectively arranged at a first side edge and a second side edge of the base, the elastic arm is connected with a third side edge of the base, a contact head is arranged on the elastic arm and protrudes relative to the elastic arm, the elastic arm is arranged near to the base when an external force is applied to the contact head, and the elastic arm deviates from the base when the external force disappears. The electronic equipment comprises the elastic sheet, wherein the elastic sheet is arranged on a PCB and is in contact with a gold finger on a metal frame. The elastic sheet is simple to process and manufacture, is stable to use and is relatively good in reliability and relatively small in size, the size of a protruding structure of the metal frame can be obviously reduced, the occupancy clearance size of an antenna is reduced, and the antenna performance is improved.

The subject invention discloses a sealing assembly that includes a first component and a second component moveable into and out of mating engagement to form a seal therebetween. The first component has a first sealing surface defining a groove and a sealing bead extends upwardly a predetermined height therefrom. The sealing bead is molded within the groove. The second component has a second sealing surface defining a recess for contacting the sealing bead. When the first and the second components are brought into mating engagement, the sealing bead compresses at most 40% of the predetermined height when the second sealing surface contacts the sealing bead.

The invention discloses a labor protection glove. The labor protection glove comprises a glove body which is made of white terylene threads through knitting and a portion (indicated as A in Figure 1) and a portion (indicated as B in Figure 1) on the glove body; the labor protection glove is characterized in that a connecting portion of two 'finger sleeves' of 'the third finger' and 'the little finger' of the glove body is deepened downwards by 15mm, and a portion of the 'finger sleeve' of the little finger of the glove body is widened by 5mm, so that the labor protection glove is formed. The novel labor protection glove has the advantages that the usage time of the glove is prolonged.

The invention relates to the use of a composition containing, in a physiologically acceptable medium having an aqueous phase, at least one oxidation-sensitive hydrophilic active principle selected from the group consisting of ascorbic acid and its derivatives and at least one non-crosslinked N-vinylimidazole polymer or copolymer, the active principle and the polymer or copolymer both being in the aqueous phase, for preventing or combatting the harmful effects of UV radiation and / or of pollution on the skin, in particular loss of firmness and / or of elasticity of the skin.

The invention belongs to the field of drugs, health care products or food, and particularly relates to a composition with both roles of weight losing and facial features beautifying and a preparing method and an application thereof. The composition is prepared from, by weight, 3-15 parts of L-threonic acid magnesium, 6-20 parts of arabinose, 0.5-8 parts of lemon extractive, 1-15 parts of collagen peptide, 1-9 parts of grapefruit extractive and 0.1-5 parts of guarana extractive. The composition with both roles of weight losing and facial features beautifying takes a full consideration of the compositions of the raw materials and chooses the ratios among the raw materials, thus making the raw materials coordinate with each other and play the roles together according to the ratios; in addition, the composition not only plays the role of weight losing, but also can improve the luster and the elasticity of the skin at the time of weight losing so that the skin will not lose elasticity and generate collapse because of fat reducing, thus playing the role of facial features beautifying at the same time.

Compositions, methods, and processes are used in topical applications for human or animal skin. A combination of five (5) active ingredients: caffeine, trehalose, asparagus extract, ceramide 2 (2%) and a resurrection plant, Myrothamnus flabellifolia, extract are used in a topical formulation, such as a cream, lotion, spray or gel to boost or activate autophagy, the body's innate processes for repairing cell damage. The five active ingredients are combined in different formulations to provide at least six (6) products for topical application, including, but not limited to, a cleanser, a spray essence, a day cream, a night cream, a serum and a booster. The five (5) active ingredients provide a unique biological composition, hereinafter called, “autophagy activating complex,” that changes the way skin ages, restores and renews radiance.

The invention relates to a gigohm-level anti-explosion and combustion-proof cover cap of a power battery. The gigohm-level anti-explosion and combustion-proof cover cap comprises an upper cover cap, an anti-explosion membrane with a wall body, a perforated plate, an inner sealing ring and an outer sealing ring, wherein the upper cover cap is arranged on the upper end face of the anti-explosion membrane and is inwards bent and pressed from the wall body in a state of being ultrasonically welded on the upper end face of the upper cover cap by multiple points; a plurality of air holes are uniformly formed in the upper cover cap; a turnover prestress release buckle connected to the upper cover cap is arranged in each air hole; the lower end face of the anti-explosion membrane is welded with the perforated plate; the outer sealing ring is glued to cover the outer walls of the upper cover cap and the anti-explosion membrane; the upper and lower edges of the outer sealing ring are inwards bent and glued to press the upper cover cap or the upper end face of the bent wall body of the anti-explosion membrane and the lower end face of the anti-explosion membrane. The gigohm-level anti-explosion and combustion-proof cover cap is characterized in that a plurality of pressure release lines respectively corresponding to the multiple turnover prestress release buckles are uniformly distributed on the anti-explosion membrane; the pressure release lines are non-closed single arc-shaped curves, or two or more than two pressure release lines with structures intersected at one point.