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45results about How to "Extensive interaction" patented technology

Cell flow apparatus and method for real-time of cellular responses

An apparatus and method for real-time measurement of a cellular response of a test compound or series of test compounds (303) on a flowing suspension of cells (349), in which a homogeneous suspension of each member of a series of cell types (349) is combined with a concentration of a test compound (303), directed through a detection zone (355), and a cellular response of the living cells is measured in real time as the cells in the test mixture are flowing through the detection zone (355). The apparatus may be used in automated screening of libraries of compounds, and is capable of real-time variation of concentrations of test and standard compounds and generation of dose / response profiles within a short time span.
Owner:CAPLIPER LIFE SCI INC

Yb: and Nd: mode-locked oscillators and fiber systems incorporated in solid-state short pulse laser systems

The invention describes classes of robust fiber laser systems usable as pulse sources for Nd: or Yb: based regenerative amplifiers intended for industrial settings. The invention modifies adapts and incorporates several recent advances in FCPA systems to use as the input source for this new class of regenerative amplifier.
Owner:IMRA AMERICA

Cell flow apparatus and method for real-time measurements of cellular responses

An apparatus and method for real-time measurement of a cellular response of a test compound or series of test compounds (303) on a flowing suspension of cells (349), in which a homogeneous suspension of each member of a series of cell types (349) is combined with a concentration of a test compound (303), directed through a detection zone (355), and a cellular response of the living cells is measured in real time as the cells in the test mixture are flowing through the detection zone (355). The apparatus may be used in automated screening of libraries of compounds, and is capable of real-time variation of concentrations of test and standard compounds and generation of dose / response profiles within a short time span.
Owner:CAPLIPER LIFE SCI INC

Antimicrobial charged polymers that exhibit resistance to lysosomal degradation during kidney filtration and renal passage, compositions and method of use thereof

InactiveUS20030181416A1Minimizing spreadMinimizing worseningAntibacterial agentsBiocideSulfated polysaccharidesLysosome
Methods and compositions for treating or preventing microbial infection in mammals with sulfated polysaccharides wherein the polysaccharides have a degree of sulfation effective to enable maximal interaction of constituent sulfate groups with the microbe which causes the infection and wherein the sulfated polysaccharide is not substantially endocytosed or degraded by cell receptor binding in the mammal and thereby retains antimicrobial activity in vivo.
Owner:MONASH UNIV

Method and apparatus for generating combustible synthesis gas

The present application discloses an apparatus for gasification of solid, liquid and gaseous organic feed materials having a fuel value into synthesis gas. The apparatus comprises: a gasification reactor vessel having a tapered interior with a minimum of four zones for introducing reaction gas mixtures, a central perforated diffuser pipe, a solid and liquid material inlet at the upper end of the uppermost zone, a solid and gas discharge outlet at the lower end of the bottom zone, wherein the reactor vessel defining a sequence of reaction zones from the material inlet to the material outlet including drying, pyrolysis, combustion and gasification zones, and confining downwardly moving the column of the feed materials within the zones, gas feed inlet pipes for introducing reaction gas into the zones, a synthesis gas discharge pipe below the zones, and a heat exchanger below the zones.
Owner:JC ENVIRO ENTERPRISES CORP

Yb: and Nd: mode-locked oscillators and fiber systems incorporated in solid-state short pulse laser systems

The invention describes classes of robust fiber laser systems usable as pulse sources for Nd: or Yb: based regenerative amplifiers intended for industrial settings. The invention modifies adapts and incorporates several recent advances in FCPA systems to use as the input source for this new class of regenerative amplifier.
Owner:IMRA AMERICA

Modular seed treatment apparatus

The apparatus of the invention is directed toward a modular seed treatment apparatus that is capable of receiving various component pieces of equipment for application of liquid treatment compositions and powders to seeds on a frame assembly to accommodate the various component pieces. The apparatus of the invention is further directed toward a modular seed treatment apparatus that is capable of receiving a treatment container for treatment of various small quantities of seed including 0.5 to two pounds, two to five pounds and 5 to 10 pounds of seed.
Owner:GUSTAFSON INC

Methods and devices for targeting a site in a mammal and for removing species from a mammal

Methods and devices for improved targeting to a site in an organism, particularly to a tumor target site and for extracorporeal affinity adsorption, particularly in the treatment of cancer, atherosclerosis, including coronary artery disease, unstable angina, other acute ischemic syndromes and idiopathic dilated cardiac myopathy. In one aspect of the invention, a combination is provided comprising an extracorporeal device (1) having contained therein a binding compound (11) bound to a carrier (9), the binding compound having affinity for a binding partner, and a plurality of affinity binders (15), each of said affinity binders comprising a first portion (19) comprising the binding partner and a second portion (17) adapted to bind selectively with a species, the second portions of each of said affinity binders differing from each other.
Owner:STRAHILEVITZ MEIR

Monolithic all-semiconductor optically addressed spatial light modulator based on low-photoconductive semiconductors

An optically addressed spatial light modulator (OASLM), and an optical pattern processor employing the same. An embodiment of the OASLM includes a transparent electrode; a buffer layer; a detector region; and a modulator region, wherein the detector and modulator regions are optically isolated and resist electron movement therebetween. In one embodiment, the detector region includes a photoconductive semiconductor region with a higher band gap than the modulator region and the modulator region comprises a low-photoconductive semiconductor material.
Owner:CIENA

Flourescent organic nanofibrils as sensory materials for explosives detection

The present invention relates to a class of fluorescent, organic nanofibrils, and particularly the films comprising entangled piling of these nanofibrils exhibiting effective quenching of their fluorescence upon exposure the vapor of explosives. The invention also relates to a sensor and a method for sensing the explosives vapor and other volatile organic compounds, including the explosives taggants through the modulation of the fluorescence of the nanofibril film and the electrical conductivity of the nanofibrils. The invention also relates to a development of synthetic methods, protocols and techniques that leads to production of various arylene-ethynylene macrocycle (AEM) molecules, which consist of a shape-persistent, toroidal scaffold in planar conformation, with minimal ring strain and highly tunable ring sizes (from 0.5 nm to above 10 nm). The invention also relates to an approach to optimization of the one-dimensional molecular arrangement along the long axis of the nanofibril, which provides increased exciton (excited state) migration (via cofacial intermolecular electronic coupling) and charge transport (via pi-electronic delocalization). A combination of long-range exciton migration and efficient charge transport makes the nanofibrils ideal as sensory materials for detecting explosives and other volatile organic compounds through both optical and electrical sensing mechanisms.
Owner:SOUTHERN ILLINOIS UNIVERSITY

Network application program interface facilitating communication in a distributed network environment

A request broker receives a request from a client, including a description of a method and parameters to be used in executing the method. The parameters have one of multiple acceptable native formats. The request broker determines the native format and communicates the parameters in the native format to a selected one of multiple translators for translation to an internal format, where each translator is associated with a different native format. The request broker communicates the parameters in the internal format to an application server system to enable execution of the method, receives a return value from the application server system reflecting execution of the method, communicates the return value in the internal format to the selected translator for translation to the native format, generates a reply including the description of the method and the return value in the native format, and communicates the reply to the client.
Owner:JDA SOFTWARE GROUP

Anti-Fouling Coatings for Combustion System Components Exposed to Slag, Ash and/or Char

A coating for use in combustion systems includes a plurality of refractory metal particles in a ceramic, glass or metal matrix disposed on surfaces of the system that are prone to slag, ash, and / or char buildup during operation of the combustion system. The coating is effective to prevent any substantial interaction with the slag, ash, and / or char.
Owner:THE PROCTER & GAMBNE CO +1

Charged polysaccharides resistant to lysosomal degradation during kidney filtration and renal passage and their use to treat or prevent infection by coronaviruses

This invention relates to methods for treating, preventing or managing coronavirus infections in mammals using sulfated polysaccharides. More particularly, this invention relates to methods of treating, preventing or managing infection by coronaviruses, particularly viral infections leading to or causing diseases such as the newly discovered Severe Acute Respiratory Syndrome (“SARS”). The invention involves the use of sulfated polysaccharides which are abundant, non-toxic and inexpensive and which are potent antivirals in vivo.
Owner:MONASH UNIV

System and method for uploading 3D (three-dimensional) video to video website by user

The invention discloses a system for uploading a 3D (three-dimensional) video to a video website by a user. The system is characterized by comprising the following modules: a user uploading platform (1) for uploading the video and carrying out classified identification on the video, a website video processing background (2) for carrying out content auditing, 3D auditing and 3D video transcode operation on the video on the background, a middle layer (3) for adding a 3D attribute label to the 3D video, a website front end (4) for returning video meta information and providing related information of the 3D video to a website user and a player, and a front end player (5) for carrying out 3D video playing according to the attribute label of the video marked to be 3D, and forming a final 3D video on the website for watching by the user.
Owner:ALIBABA (CHINA) CO LTD

Compounds and methods for treating HIV

Inhibitors of HIV-1 protease and compositions containing them are described. Use of the inhibitors and compositions containing them to treat HIV, AIDS, and AIDS-related diseases is described.
Owner:PURDUE RES FOUND INC

Method and apparatus for generating combustible synthesis gas

The present application discloses an apparatus for gasification of solid, liquid and gaseous organic feed materials having a fuel value into synthesis gas. The apparatus comprises: a gasification reactor vessel having a tapered interior with a minimum of four zones for introducing reaction gas mixtures, a central perforated diffuser pipe, a solid and liquid material inlet at the upper end of the uppermost zone, a solid and gas discharge outlet at the lower end of the bottom zone, wherein the reactor vessel defining a sequence of reaction zones from the material inlet to the material outlet including drying, pyrolysis, combustion and gasification zones, and confining downwardly moving the column of the feed materials within the zones, gas feed inlet pipes for introducing reaction gas into the zones, a synthesis gas discharge pipe below the zones, and a heat exchanger below the zones.
Owner:JC ENVIRO ENTERPRISES CORP

Fluorescent organic nanofibrils as sensory materials for explosives detection

InactiveUS20120288950A1Efficiently quenchedMinimal ring strainMaterial analysis by electric/magnetic meansNanosensorsFiberSynthesis methods
A class of fluorescent, organic nanofibrils, and particularly the films comprising entangled piling of these nanofibrils exhibiting effective quenching of their fluorescence upon exposure the vapor of explosives is disclosed. A sensor and a method for sensing the explosives vapor and other volatile organic compounds is disclosed, including the explosives taggants through the modulation of the fluorescence of the nanofibril film and the electrical conductivity of the nanofibrils. A development of synthetic methods is disclosed, such as protocols and techniques that lead to the production of various arylene-ethynylene macrocycle (AEM) molecules, which consist of a shape-persistent, toroidal scaffold in planar conformation, with minimal ring strain and highly tunable ring sizes (from 0.5 nm to above 10 nm). An approach to optimization of the one-dimensional molecular arrangement along the long axis of the nanofibril is also disclosed, which provides increased exciton migration and charge transport (via pi-electronic delocalization).
Owner:SOUTHERN ILLINOIS UNIVERSITY

Antimicrobial charged polymers that exhibit resistance to lysosomal degradation during kidney filtration and renal passage, compositions and method of use thereof

Methods and compositions for treating or preventing microbial infection in mammals with sulfated polysaccharides wherein the polysaccharides have a degree of sulfation effective to enable maximal interaction of constituent sulfate groups with the microbe which causes the infection and wherein the sulfated polysaccharide is not substantially endocytosed or degraded by cell receptor binding in the mammal and thereby retains antimicrobial activity in vivo.
Owner:MONASH UNIV

Flourescent organic nanofibrils based on arylene-ethylene macrocycles as sensory materials for explosives detection

ActiveUS8153065B2Efficiently quenchedMinimal ring strainAnalysis using chemical indicatorsAnalysis by electrical excitationFiberFluorescence
The present invention relates to a class of fluorescent, organic nanofibrils, and particularly the films comprising entangled piling of these nanofibrils exhibiting effective quenching of their fluorescence upon exposure the vapor of explosives. The invention also relates to a sensor and a method for sensing the explosives vapor and other volatile organic compounds, including the explosives taggants through the modulation of the fluorescence of the nanofibril film and the electrical conductivity of the nanofibrils. The invention also relates to a development of synthetic methods, protocols and techniques that leads to production of various arylene-ethynylene macrocycle (AEM) molecules, which consist of a shape-persistent, toroidal scaffold in planar conformation, with minimal ring strain and highly tunable ring sizes (from 0.5 nm to above 10 nm). The invention also relates to an approach to optimization of the one-dimensional molecular arrangement along the long axis of the nanofibril, which provides increased exciton (excited state) migration (via cofacial intermolecular electronic coupling) and charge transport (via pi-electronic delocalization). A combination of long-range exciton migration and efficient charge transport makes the nanofibrils ideal as sensory materials for detecting explosives and other volatile organic compounds through both optical and electrical sensing mechanisms.
Owner:SOUTHERN ILLINOIS UNIVERSITY

Cap/endo dual inhibitors and their use in the treatment, amelioration or prevention of a viral disease

InactiveUS9827244B2Increasing ligand efficiency and selectivityInfluence overall polarityOrganic active ingredientsOrganic chemistryMedicineEnantiomer
The present invention relates to a compound having the general formula (V), optionally in the form of a pharmaceutically acceptable salt, solvate, polymorph, codrug, cocrystal, prodrug, tautomer, racemate, enantiomer, or diastereomer or mixture thereof,which are useful in treating, ameloriating or preventing a viral disease. Furthermore, specific combination therapies are disclosed.
Owner:F HOFFMANN LA ROCHE & CO AG +2

Antiviral charged polymers that exhibit resistance to lysosomal degradation during kidney filtration and renal passage, compositions and methods of use thereof

The invention provides methods and compositions for treating, preventing or managing a viral infection in a subject comprising administering one or more sulfated polysaccharides, wherein the polysaccharides have a percent of sulfur with respect to the sugar residue effective to enable maximal interaction of constituent sulfate groups with the microbe which causes the infection and wherein the sulfated polysaccharide is not substantially endocytosed or degraded by cell receptor binding in the mammal and thereby retains antimicrobial activity in vivo. The invention also provides methods and compositions for treating, preventing or managing a non-viral. microbial infection in a subject comprising administering one or more substituted polysaccharides.
Owner:MONASH UNIV

Antimicrobial charged polymers that exhibit resistance to lysosomal degradation during kidney filtration and renal passage, compositions and method of use thereof

InactiveUS20070027109A1Reducing and avoiding adverse effectRetain activityBiocideOrganic active ingredientsSulfated polysaccharidesFiltration
Methods and compositions for treating or preventing microbial infection in mammals with sulfated polysaccharides wherein the polysaccharides have a degree of sulfation effective to enable maximal interaction of constituent sulfate groups with the microbe which causes the infection and wherein the sulfated polysaccharide is not substantially endocytosed or degraded by cell receptor binding in the mammal and thereby retains antimicrobial activity in vivo.
Owner:MONASH UNIV

Antimicrobial charged polymers that exhibit resistance to lysosomal degradation during kidney filtration and renal passage, compositions and method of use thereof

Methods and compositions for treating or preventing microbial infection in mammals with sulfated polysaccharides wherein the polysaccharides have a degree of sulfation effective to enable maximal interaction of constituent sulfate groups with the microbe which causes the infection and wherein the sulfated polysaccharide is not substantially endocytosed or degraded by cell receptor binding in the mammal and thereby retains antimicrobial activity in vivo.
Owner:MONASH UNIV
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