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1679results about "Magnetic variable regulation" patented technology

Method and system for predictive physiological gating

A method and system for physiological gating is disclosed. A method and system for detecting and predictably estimating regular cycles of physiological activity or movements is disclosed. Another disclosed aspect of the invention is directed to predictive actuation of gating system components. Yet another disclosed aspect of the invention is directed to physiological gating of radiation treatment based upon the phase of the physiological activity. Gating can be performed, either prospectively or retrospectively, to any type of procedure, including radiation therapy or imaging, or other types of medical devices and procedures such as PET, MRI, SPECT, and CT scans.
Owner:VARIAN MEDICAL SYSTEMS

Method and kit for imaging and treating organs and tissues

Provided are methods and compositions for detecting and treating normal, hypoplastic, ectopic or remnant tissue, organ or cells in a mammal. The method comprises parenterally injecting a mammalian subject, at a locus and by a route providing access to above-mentioned tissue or organ, with an composition comprising antibody / fragment which specifically binds to targeted organ, tissue or cell. The antibody / fragment may be administered alone, or labeled or conjugated with an imaging, therapeutic, cytoprotective or activating agent.
Owner:IMMUNOMEDICS INC

Systems and methods for evaluating the urethra and the periurethral tissues

The present invention provides systems and methods for the evaluation of the urethra and periurethral tissues using an MRI coil adapted for insertion into the male, female or pediatric urethra. The MRI coil may be in electrical communication with an interface circuit made up of a tuning-matching circuit, a decoupling circuit and a balun circuit. The interface circuit may also be in electrical communication with a MRI machine. In certain practices, the present invention provides methods for the diagnosis and treatment of conditions involving the urethra and periurethral tissues, including disorders of the female pelvic floor, conditions of the prostate and anomalies of the pediatric pelvis.
Owner:THE JOHN HOPKINS UNIV SCHOOL OF MEDICINE +1

MRI and RF compatible leads and related methods of operating and fabricating leads

RF / MRI compatible leads include at least one conductor that turns back on itself at least twice in a lengthwise direction, and can turn back on itself at least twice at multiple locations along its length. The at least one electrical lead can be configured so that the lead heats local tissue less than about 10 degrees Celsius (typically about 5 degrees Celsius or less) or does not heat local tissue when a patient is exposed to target RF frequencies at a peak input SAR of at least about 4 W / kg and / or a whole body average SAR of at least about 2 W / kg. Related devices and methods of fabricating leads are also described.
Owner:MRI INTERVENTIONS INC +1

Biopsy apparatus

InactiveUS20050113715A1Eliminate riskMaximizes length and overall size of coreSurgical needlesVaccination/ovulation diagnosticsPneumatic circuitMedicine
A disposable tissue removal device comprises a “tube within a tube” cutting element mounted to a handpiece. The inner cannula of the cutting element defines an inner lumen and terminates in an inwardly beveled, razor-sharp cutting edge. The inner cannula is driven by both a pneumatic rotary motor and a pneumatic reciprocating motor. At the end of its stroke, the inner cannula makes contact with the cutting board to completely sever the tissue. An aspiration vacuum is applied to the inner lumen to aspirate excised tissue through the inner cannula and into a collection trap removably mounted to the handpiece. The rotary and reciprocating motors are hydraulically or pneumatically powered through a foot pedal operated pneumatically circuit. In one embodiment, the cutting element includes a cannula hub that can be connected to a fluid source, such as a valve-controlled saline bag.
Owner:TISSUE EXTRACTION DEVICES

Method and apparatus for medical intervention procedure planning

An imaging system for use in medical intervention procedure planning includes a medical scanner system for generating a volume of cardiac image data, a data acquisition system for acquiring the volume of cardiac image data, an image generation system for generating a viewable image from the volume of cardiac image data, a database for storing information from the data acquisition and image generation systems, an operator interface system for managing the medical scanner system, the data acquisition system, the image generation system, and the database, and a post-processing system for analyzing the volume of cardiac image data, displaying the viewable image and being responsive to the operator interface system. The operator interface system includes instructions for using the volume of cardiac image data and the viewable image for bi-ventricular pacing planning, atrial fibrillation procedure planning, or atrial flutter procedure planning.
Owner:GENERAL ELECTRIC CO +1

MR imaging method and medical device for use in method

The invention relates to an MR imaging method for representing and determining the position of a medical device inserted in an examination object, and to a medical device used in the method. In accordance with the invention, the device (11) comprises at least one passive oscillating circuit with an inductor (2a, 2b) and a capacitor (3a, 3b). The resonance frequency of this circuit substantially corresponds to the resonance frequency of the injected high-frequency radiation from the MR system. In this way, in a locally limited area situated inside or around the device, a modified signal answer is generated which is represented with spatial resolution.
Owner:AMRIS PATENTE VERW

Production and use of novel peptide-based agents for use with bi-specific antibodies

The present invention relates to a bi-specific antibody or antibody fragment having at least one arm that is reactive against a targeted tissue and at least one other arm that is reactive against a linker moiety. The linker moiety encompasses a hapten to which antibodies have been prepared. The antigenic linker is conjugated to one or more therapeutic or diagnostic agents or enzymes. The invention provides constructs and methods for producing the bispecific antibodies or antibody fragments, as well as methods for using them.
Owner:IMMUNOMEDICS INC

System and method for magnetic-resonance-guided electrophysiologic and ablation procedures

InactiveUS7155271B2Increased resolution and reliabilityImprove accuracySurgical instrument detailsDiagnostic recording/measuringMr guidanceMr contrast agent
A system and method for using magnetic resonance imaging to increase the accuracy of electrophysiologic procedures is disclosed. The system in its preferred embodiment provides an invasive combined electrophysiology and imaging antenna catheter which includes an RF antenna for receiving magnetic resonance signals and diagnostic electrodes for receiving electrical potentials. The combined electrophysiology and imaging antenna catheter is used in combination with a magnetic resonance imaging scanner to guide and provide visualization during electrophysiologic diagnostic or therapeutic procedures. The invention is particularly applicable to catheter ablation, e.g., ablation of atrial fibrillation. In embodiments which are useful for catheter ablation, the combined electrophysiology and imaging antenna catheter may further include an ablation tip, and such embodiment may be used as an intracardiac device to both deliver energy to selected areas of tissue and visualize the resulting ablation lesions, thereby greatly simplifying production of continuous linear lesions. The invention further includes embodiments useful for guiding electrophysiologic diagnostic and therapeutic procedures other than ablation. Imaging of ablation lesions may be further enhanced by use of MR contrast agents. The antenna utilized in the combined electrophysiology and imaging catheter for receiving MR signals is preferably of the coaxial or “loopless” type. High-resolution images from the antenna may be combined with low-resolution images from surface coils of the MR scanner to produce a composite image. The invention further provides a system for eliminating the pickup of RF energy in which intracardiac wires are detuned by filtering so that they become very inefficient antennas. An RF filtering system is provided for suppressing the MR imaging signal while not attenuating the RF ablative current. Steering means may be provided for steering the invasive catheter under MR guidance. Other ablative methods can be used such as laser, ultrasound, and low temperatures.
Owner:THE JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE

Integrated high-frequency generator system utilizing the magnetic field of the target application

ActiveUS8786284B2Easily and simply adapted for DNP operationSmall and compactMeasurements using double resonanceTubes with helical electron streamInternal modeMicrowave
An integrated high-frequency generator system utilizing the magnetic field of the target application including a magnetic resonance magnet having an application zone and a high-frequency (microwave / terahertz) generator zone in the magnetic field of the magnetic resonance magnet; and a high-frequency (microwave / terahertz) generator disposed in the high-frequency (microwave / terahertz) generator zone and utilizing the magnet field of the magnetic resonance magnet to generate the high-frequency (microwave / terahertz) radiation. The magnetic resonance magnet may have an auxiliary magnetic field source for modifying the magnetic field profile in the high-frequency (microwave / terahertz) generator zone. The high-frequency (microwave / terahertz) generator may include an electron gun for generating an electron beam adapted to be focused by a magnetic field source having a spatially rising region, a homogenous region and a decaying region, an interaction structure for generating high-frequency (microwave / terahertz) radiation, an internal mode converter in the homogenous region for extracting the high-frequency (microwave / terahertz) radiation through a window, and a reduced collector disposed substantially in the homogenous region before the electron beam spreads in the decaying region.
Owner:BRIDGE 12 TECH

Method for Configuring an IC Card in Order to Receive Personalization Commands

An IC card is configured to receive personalization commands which are used to transmit data to the IC card. An access control list is associated with the data. The data is stored in the IC card in a record structure that includes a plurality of entries. The access control list is stored in the IC card in the record structure. The personalization commands include a card personalization specification (CPS).
Owner:STMICROELECTRONICS INT NV

Device and method for preventing magnetic resonance imaging induced damage

An electromagnetic shield has a first patterned or apertured layer having non-conductive materials and conductive material and a second patterned or apertured layer having non-conductive materials and conductive material. The conductive material may be a metal, a carbon composite, or a polymer composite. The non-conductive materials in the first patterned or apertured layer may be randomly located or located in a predetermined segmented pattern such that the non-conductive materials in the first patterned or apertured layer are located in a predetermined segmented pattern with respect to locations of the non-conductive materials in the second patterned or apertured layer.
Owner:MEDTRONIC INC

Energy shunt for producing an MRI-safe implantable medical device

A neurostimulation system is configured for implantation into a patient's body and comprises a neurostimulator, a conductive stimulation lead having a first proximal end and a first distal end, at least one distal electrode electrically coupled proximate the first distal end, and a lead extension having a second proximal end electrically coupled to the neurostimulator and having a second distal end electrically coupled to the first proximal end. A shunt is electrically coupled to the first proximal end for diverting RF energy from the lead.
Owner:MEDTRONIC INC

Method and apparatus for reducing contamination of an electrical signal

The method of reducing contamination of electrical signals recorded in the presence of repeated interference contamination comprises obtaining an electrical signal recorded in the presence of a contaminating signal, and detecting a timing signal that occurs at a fixed time point during the electrical signal relative to the onset of the contaminating signal. The electrical signal is digitized, wherein the digitizing begins with the timing signal. A plurality of digitized electrical signals is analyzed, wherein the electrical signals are synchronized with respect to the timing signal, to obtain an estimated contaminating signal that is subtracted from the digitized electrical signal. This method can be used with electrophysiological signals, such as EEG, ECG, EMG and galvanic skin response, and for elimination of noise associated with concurrently used methods such as MRI. The method of noise reduction is applicable to recordings of other electrical signals, including audio recordings.
Owner:RGT UNIV OF CALIFORNIA

Workflow configuration and execution in medical imaging

A computer-implemented method and apparatus is provided for workflow configuration and execution in medical imaging. One method embodiment comprises the steps of creating and storing a workflow template (the workflow template comprising a standard form for entering data and activities), filling out the workflow template with data and a sequence of activities, and executing the sequence of activities according to the workflow template.
Owner:KK TOSHIBA +1

Systems and methods for evaluating the urethra and the periurethral tissues

The present invention provides systems and methods for the evaluation of the urethra and periurethral tissues using an MRI coil adapted for insertion into the male, female or pediatric urethra. The MRI coil may be in electrical communication with an interface circuit made up of a tuning-matching circuit, a decoupling circuit and a balun circuit. The interface circuit may also be in electrical communication with a MRI machine. In certain practices, the present invention provides methods for the diagnosis and treatment of conditions involving the urethra and periurethral tissues, including disorders of the female pelvic floor, conditions of the prostate and anomalies of the pediatric pelvis.
Owner:THE JOHN HOPKINS UNIV SCHOOL OF MEDICINE +1

MRI-guided temperature mapping of tissue undergoing thermal treatment

Systems and methods using magnetic resonance imaging for monitoring the temperature of a tissue mass being heated by energy converging in a focal zone that is generally elongate and symmetrical about a focal axis. A first plurality of images of the tissue mass are acquired in a first image plane aligned substantially perpendicular to the focal axis. A cross-section of the focal zone in the first image plane is then defined from the first plurality of images. A second plurality of images are acquired of the tissue mass in a second image plane aligned substantially parallel to the focal axis, the second image plane bisecting the first image plane at approximately a midpoint of the defined focal zone cross-section.
Owner:INSIGHTEC

Magnetic resonance imaging having patient video, microphone and motion tracking

Critical needs for MRI patient instruction, testing, comfort, motion control, and speech communication are provided for better imaging which leads to more effective medical care. An MRI Digital Video Projection System is disclosed which provides better quality display to the patient to better inform, instruct, test, and comfort the patient plus the potential to stimulate the brain with microsecond onset times to better diagnose brain function. An MRI Motion Tracker and Patient Augmented Visual Feedback System enables monitoring patient body part motion, providing real time feedback to the patient and / or technician to substantially improve diagnostic yield of scanning sessions, particularly for children and mentally challenged individuals. An MR Forward Predictive Noise Canceling Microphone System removes the intense MRI acoustic noise improving patient communication, patient safety and enabling coding of speech output. These systems can be used individually but maximum benefit is from providing all three.
Owner:PITTSBURGH UNIV OF +1

Black blood angiography method and apparatus

To produce a black body angiographic image representation of a subject (42), an imaging scanner (10) acquires imaging data that includes black blood vascular contrast. A reconstruction processor (38) reconstructs a gray scale image representation (100) from the imaging data. A post-acquisition processor (46) transforms (130) the image representation (100) into a pre-processed image representation (132). The processor (46) assigns (134) each image element into one of a plurality of classes including a black class corresponding to imaged vascular structures, bone, and air, and a gray class corresponding to other non-vascular tissues. The processor (46) averages (320) intensities of the image elements of the gray class to obtain a mean gray intensity value (322), and replaces (328) the values of image elements comprising non-vascular structures of the black class with the mean gray intensity value.
Owner:KONINKLIJKE PHILIPS ELECTRONICS NV +1

Band stop filter employing a capacitor and an inductor tank circuit to enhance MRI compatibility of active medical devices

InactiveUS20060247684A1Decrease QCapacitor is relatively minimizedMultiple-port networksInternal electrodesCapacitanceEngineering
A band stop filter is provided for a lead wire of an active medical device (AMD). The band stop filter includes a capacitor in parallel with an inductor. The parallel capacitor and inductor are placed in series with the lead wire of the AMD, wherein values of capacitance and inductance are selected such that the band stop filter is resonant at a selected frequency. The Q of the inductor may be relatively maximized and the Q of the capacitor may be relatively minimized to reduce the overall Q of the band stop filter to attenuate current flow through the lead wire along a range of selected frequencies. In a preferred form, the band stop filter is integrated into a TIP and / or RING electrode for an active implantable medical device.
Owner:WILSON GREATBATCH LTD

Magnetic resonance imaging interference immune device

InactiveUS20040263174A1Reduce the impactReducing the effects of induced voltages upon a deviceMultiple-port networksInternal electrodesCharacteristic impedanceVoltage compensation
A voltage compensation unit reduces the effects of induced voltages upon a device having a single wire line. The single wire line has balanced characteristic impedance. The voltage compensation unit includes a tunable compensation circuit connected to the wire line. The tunable compensation circuit applies supplemental impedance to the wire line. The supplemental impedance causes the characteristic impedance of the wire line to become unbalanced, thereby reducing the effects of induced voltages caused by changing magnetic fields.
Owner:MEDTRONIC INC

Magnetic resonance scanner with electromagnetic position and orientation tracking device

A system for combining electromagnetic position and orientation tracking with magnetic resonance scanner is provided. One embodiment includes a magnetic resonance scanner defining a reference coordinate system for scanning a target. Coupled to the magnetic resonance scanner is a magnetic field source which produces a magnetic field. The magnetic field is sensed by a magnetic field sensor which produces a signal proportional to the magnetic field. The magnetic field sensor has a location relative to the reference coordinate system. The location of the magnetic field sensor relative to the reference coordinate system of the magnetic resonance scanner is determined by a location tracking device using at least a line segment model of the magnetic field source and the signal from the magnetic field sensor.
Owner:JAKAB PETER D
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