72 results about "Tumor biopsy" patented technology

A device and method of use for securing and coring of tumors within the body during a biopsy of the tumor, specifically breast tumors. An adhesion probe for securing the tumor is described. The probe secures the tumor by piercing the tumor and providing a coolant to the distal tip to cool the tip. The cooled tip adheres to the tumor. A coring instrument adapted for cutting a core sample of the tumor is described. The instrument is provided with a cannula that can cut a core sample of the tumor. The instrument is adapted for use with the probe with the probe fitting within the cannula. The instrument can be used in conjunction with the probe to secure and core a sample of the tumor for biopsy.

Multi-modal approaches to predict tumor immune infiltration are based on integrating gene expression data and imaging features in a neural network-based framework. This framework is configured to estimate percent composition, and thus immune infiltration score, of a patient tumor biopsy sample. Multi-modal approaches may also be used to predict cell composition beyond immune cells via integrated multi-layer neural network frameworks.

The invention discloses a body surface tumor biopsy sampler, which comprises a holding sleeve, a pressing handle, a stable ring and a sampling head. A pair of vertical connecting rods are installed on the outer surface of the holding sleeve, and the connecting rods The bottom is jointly connected with a horizontal stable ring, the inside of the holding sleeve is provided with a vertically penetrating sliding channel, the middle of the pressing handle is symmetrically fixed with lower pressing blocks on both sides, and the holding sleeve passes through the sliding channel It is sleeved outside the pressing handle, and the side of the lower pressing block is in contact with the inner wall of the sliding channel. The pressing handle is covered with a spring. The upper surface of the platform extending from the inner lower part of the pipe to the central axis is abutted and connected. The body surface tumor biopsy sampler has a simple structure, strong integrity, can be operated with one hand, reduces the damage caused by human factors in the sampling process, is more stable, is simple and convenient to replace the sampling head, and has popularization value.

The invention discloses a tumor biopsy sampling device for medical clinic. The device comprises a sampling device body and a sampling cylinder, a storage box is fixedly arranged on the surface of theupper end of the sampling device body, a hydraulic pump is fixedly arranged on the surface of the lower end in the storage box, a hydraulic rod is arranged on one side of the hydraulic pump in a transmission manner, a supporting plate is fixedly arranged at one end of the hydraulic rod, a sampling cylinder is fixedly arranged at one end of the supporting plate, and a plurality of universal wheelsare fixedly arranged on the surface of the lower end of the sampling device body. A second stepping motor is started again to drive a needle cylinder outer sleeve hemming pressing plate to continuously descend, a sampling needle cylinder body compresses a spring, the needle head is pierced into tumor, then the compressing is stopped, at the moment, a driving motor drives an electric push rod to contract, the sampling needle cylinder pressing rod cap is clamped at the lower end of the sampling needle cylinder pressing rod cap, a piston rod is lifted and pulled to move, a sample is extracted, once the operation fails, the other needle head can be rapidly reset and replaced for sampling, shaking is avoided, the success rate is high, and the pain of a patient is reduced.

The invention discloses a device used for preventing tumor spreading after bone neoplasms biopsy, belonging to the technological field of medical instruments, which comprises a plugging body used for plugging biopsy needle passage after biopsy is made; wherein, the plugging body is made of water absorbing expandable material; a plurality of screw threads are arranged at outer surface; one end of the plugging body is plugging end; the maximum diameter of the plugging end is smaller than the diameter of the biopsy needle passage; the other end of the plugging body is an operation end; a jack or an inserting handle grafting the operation wrench along axial direction of the plugging body is arranged on the operation end; maximum diameter of the operation end is bigger than the diameter of the biopsy needle passage; central section of the plugging body is inner concave type connection rod; smooth transition is adopted between the connection rod and the plugging end and the operation end; an anti-cancer drug layer is coated on the plugging end and is used for plugging the needle passage after biopsy is made. The device used for preventing tumor spreading has the advantages of preventing tumor from flowing out from the needle passage to the peripheral of puncturing site and from causing locally spreading and metastasizing, having simple structure and convenient operation.

Described herein are micro-coil hyperpolarized NMR systems and methods for measuring metabolic flux in living and non-living samples. Such systems can perform high throughput measurements (with multiple coils) of metabolic flux without destroying the material, making it useful to analyze tumor biopsies, cancer stem cells, and the like. In certain embodiments, a hyperpolarized micromagnetic resonance spectrometer (HMRS), described herein, is used to achieve real-time, significantly more sensitive (e.g., 103-fold more sensitive) metabolic analyses of live cells or non-living samples. In this platform, a suspension mixed with hyperpolarized metabolites is loaded into a miniaturized detection coil (e.g., about 2 [mu]L), where the flux analysis can be completed within a minute without significant changes in viability. The sensitive and rapid analytical capability of the provided systems enables rapid assessment of metabolic changes by a given drug, which may direct therapeutic choices in patients.

The invention discloses an application of combined utilization of triptolide cisplatin in preparation of a pancreatic cancer drug against drug resistance. Experiments on two drug-resistant pancreatic cancer cells PANC-1 and MIAPaCa-2 and nude mice with inoculated with PANC-1 cells on flanks prove that the effects of synergistic tumor inhibition can be achieved for drug-resistant pancreatic cancer through the combined utilization of triptolide cisplatin. So far, no study on the synergistic inhibition of the pancreatic cancer through the combined utilization of triptolide cisplatin is reported. In the nude mouse xenografting model, the tumor growth can be significantly inhibited through the combined utilization of low doses of triptolide and cisplatin, and cannot be inhibited when only the triptolide or cisplatin is used. The results of immunohistochemistry for each group of tumor biopsies show that the HSP27 protein expression can be reduced significantly through the combined utilization of the two drugs, and the results are identical to the results on cell lines. Therefore, the triptolide and cisplatin can be used together as a sensitizing agent of anticancer drugs.

The invention relates to a novel detachable image-guided puncture device and a production method and application thereof. The device can be directly used for directional positioning of tumor ablation, percutaneous puncture tumor biopsy, intra-tumor intrathecal injection, intervertebral disc puncture decompression, intervertebral disc puncture ablation and the like and can be used for focuses with the depth being more than 10cm. The device can be used for performing next clinical operation flexibly and is more convenient for radio-frequency ablation and seed implantation; the device is reusable but only suitable for single-diameter needles. The device is safe, effective, easy to control, highly practical, simple in production process, low in production cost and remarkable in effect, is a significant improvement on the existing puncture device, is higher in usability and safety and easy to popularize and apply, is more suitable for large-scale production of the pharmaceuticals industry and clinical application of interventional therapy and has good application prospect, the application of the product system in the prior art is expanded, and significant social and economic benefits can be created within short time.

The invention discloses a device for preventing tumor spread after bone tumor biopsy, and belongs to the technical field of medical apparatuses. The device comprises a puncture needle, a sleeve and asampling needle; a sampling coil is fixedly connected to the outer wall of the sampling needle, multiple sampling scraping barbs are fixedly connected to the side wall of the sampling coil, a temporary storage cavity is formed in the sampling needle and located at the bottom of the sampling coil, and the puncture needle sleeves the outer wall of the sampling needle. A sealing platform is fixedly connected to the top of the puncture needle, a liquid injection channel is formed in the middle of the sealing platform, a rubber ring is fixedly connected to the end of the liquid injection channel, asealing gasket is fixedly installed at the junction of the sampling needle and the puncture needle, a sleeve sleeves the outer wall of the puncture needle, a positioning device is fixedly connected to the top of the sleeve, a push needle is matched in an inner cavity of the puncture needle, a fixed needle is fixedly connected to the end of the push needle, and a plug sleeves the outer wall of thefixed needle. By means of the device, the puncture depth is conveniently controlled. Examination tissue cannot shed or get lost, and the puncture success rate is increased. The plug absorbs drugs toplug a puncture channel, a needle passage is subjected to bleeding stopping, and tumor spread is prevented.

Systems and methods of genomic analysis are presented that provide a framework to determine a tumor's clonality, the number and proportion of all major clones, and the variants that distinguish them. Contemplated systems and methods also allow phasing mutations to parental alleles to so time their emergence within the population of tumor cells, and provide an accurate estimate of the amount of contaminating normal tissue that was present in the tumor biopsy.

The invention discloses a tumor biopsy sampling device used for clinical medicine. The device comprises a bottom cylinder which is vertically through, wherein a top base is movably connected with thetop of the bottom cylinder, butt straps are fixedly connected with both sides of the top base, a baseboard is fixedly connected with the inner wall, close to the bottom of the bottom cylinder, on thebottom cylinder, a space in a cavity of the bottom cylinder is divided into a sliding cavity and an accommodating cavity by the baseboard from top to bottom, a sliding hole is formed in the middle portion of the baseboard, a sliding rod is arranged on the inner wall of the sliding hole in a sliding mode, the bottom end of the sliding rod is movably connected with a sampling part after penetratingthrough the accommodating cavity, the top end of the sliding rod is fixedly connected with a press board after penetrating through the sliding cavity, the outer wall of the press board is connected with the inner wall of the sliding cavity in a sliding mode, a reset spring abuts against the opposite surfaces of the press board and the baseboard, a pressing rod is fixedly connected with the top ofthe press board, and the pressing rod is fixedly connected with a pressing board after penetrating through the top base. The tumor biopsy sampling device used for clinical medicine has the advantagesof being simple in structure and convenient to operate, and the problems raised in the background art are solved.

Stereotactic methods are routinely used in neurosurgery for operations such as the aspiration of brain cysts, tumor biopsies and more recently to implant electrodes into brain targets. An integral part of this surgery is a mechanical device called a stereotactic frame (10) that has head holding clamps and bars which puts the head in a fixed position in reference to the coordinate system. Various methods of accurately aligning the frame have been used but a novel device and method are proposed that over-come at least some of the shortcomings of these current techniques. There is disclosed a removable frame attachment (30) that holds the frame in position but allows for fine adjustment, allowing a single operator to quickly and accurately position the frame. The attachment can be removed before surgery without moving the set position of the frame. The device comprises two or more arms (31,32) each arm being coupled to another at a point of intersection. At least one arm comprises a plurality of fixing means (35) and at least one arm is attached to the stereotactic frame (10) using gripping means (33).

The invention discloses a bone tumor biopsy puncture needle. The bone tumor biopsy puncture needle comprises a bone puncture device, a first electric retractor, an electric rotating device and a splayed base, wherein the bone puncture device is connected to the bottom of the first electric retractor; the upper end of the first electric retractor is fixedly connected to the left side of the bottom of the electric rotating device; the electric rotating device is fixedly connected to the bottom of the base; the right side of the bottom of the electric rotating device is fixedly connected with a second electric retractor, and a second high-definition video camera is arranged at the bottom of a connecting rod; the side edge of the base is connected with a monitoring control device. Through the cooperation of the monitoring control device, the electric retractors and the electric rotating device and the unique structure of the puncture and biopsy acquiring device, a biopsy material can be accurately punctured and accurately grasped, the operation success rate is improved, and the pain of patients is reduced.

The invention discloses a device for preventing tumor progression after bone tumor biopsy. The device comprises a T-shaped plugging device which is integrally formed by a plugging head and a base, wherein the plugging head is wrapped by a layer of titanium alloy self-tapping threads; a through hole is formed between the top of the base and the bottom of the plugging head; a plugging rod with a straight line or cross shaped groove in the top and for plugging the through hole is in threaded connection with the through hole; a U-shaped hole is formed in the bottom of the plugging rod; a layer of absorbable medical membrane wraps the bottom of the U-shaped hole. With the combination of a bone substitute material and a titanium alloy, a pore channel or a needle channel left after bone tumor puncture can be permanently and tightly plugged, anti-tumor medicines can be put into the U-shaped hole in advance, and once the pore channel or the needle channel is plugged, the anti-tumor medicines can be dissolved within a certain time by using the absorbable medical membrane and has the lasting treatment effect within a partial plugged area.

The invention provides a device for preventing a tumor from spreading after bone tumor biopsy. The device comprises an occlusion bolt and an occlusion screw, a self-tapping external thread is arrangedon the outer wall of the occlusion bolt, a hollow channel is formed in the occlusion bolt, an internal thread is arranged on the inner wall of the hollow channel, and the portion, from the head to the internal thread section, of the occlusion bolt is grooved into a plurality of sections. The outer diameter of the occlusion screw is larger than the inner diameter of the occlusion bolt, the occlusion screw is matched with the internal thread of the occlusion bolt, and the sections on the head of the occlusion bolt are swelled outwards to form fixation. By means of the technology, the contamination of the tumor to the peripheral tissue can be effectively reduced, convenience is brought to micro-invasive treatment of the tumor, and the difficulty that an occlusion device is taken out in a second operation is reduced.

The invention provides a tumor biopsy apparatus, and relates to the technical field of medical apparatus and instruments. By the aid of the tumor biopsy apparatus, the problem of deficiency of tumor biopsy apparatuses suitable for extracting tumor samples during endoscopic surgery can be solved. The tumor biopsy apparatus comprises a biopsy gun and a puncture needle. The biopsy gun comprises a shell with a cavity, a sleeve is mounted in the cavity, an end of the sleeve extends out of the cavity, a first handle is mounted on the sleeve, the sleeve is provided with a puncture needle accommodating cavity along the length direction, the first handle can drive the sleeve to slide along the cavity, and a fixing assembly for fixing the puncture needle is mounted on the shell; a sample injection groove is formed in an end of the puncture needle, and the puncture needle is connected with the shell by the fixing assembly. The tumor biopsy apparatus has the advantage that tumor can be sampled by the aid of the tumor biopsy apparatus during endoscopic surgery.

The invention discloses a therapy tube device for oncology department chemoradiotherapy. The therapy tube device for oncology department chemoradiotherapy comprises a negative pressure cylinder, a needle tube is fixed to a bottom connecting opening of the negative pressure cylinder, a fixed sleeve is fixed to the outer side surface of the negative pressure cylinder, and an accumulator is installed in a cavity of the fixed sleeve; and a control switch is installed on the position, at the upper side of the fixed sleeve, of the side surface of the negative pressure cylinder, and the input end of the control switch is connected with the output end of the accumulator. According to the therapy tube device for oncology department chemoradiotherapy, partial tissue is sucked into a sucking hole of the needle tube through the negative pressure cylinder, and then a knife blade on a slide shell is utilized to conduct cutting; when tumor biopsy sampling is conducted on a patient, a sample can be prevented from being damaged, other living tissue surrounding a tumor can be protected in the sampling process, damage to other living tissue in a human body in the sampling process is avoided effectively, and the situation that serious sequelae are left to the patient can be avoided; and the structure is compact, operation can be achieved with one hand, using is convenient, and the therapy tube device is suitable for sampling pathological tissue when intracavitary tumor radiotherapy is conducted.

The invention discloses a minimally invasive channel bone tumor biopsy device, relates to the technical field of medical instruments, and solves the problems that the minimally invasive channel bone tumor biopsy device can only observe in one direction during use, a biopsy position cannot be positioned well, and the detection precision and biopsy quality will be affected. The minimally invasive channel bone tumor biopsy device comprises a mounting arm; the left arc of the mounting arm is slidably connected with a group of rotary mounting seats; the front end face of the left side of the mounting arm is fixedly connected with a set of angle adjusting driving pieces. the left portion and the lower portion of the inner side of the rotary mounting seats are respectively rotationally connected with a set of transmitting assemblies. According to the invention, imaging in two directions is achieved, meanwhile, by adjusting the installation angle of the rotary mounting seats, observation and imaging are conducted on the diseased part at different angles, the bone tumor biopsy position can be better determined, biopsy quality is guaranteed, detection accuracy is improved, unfolding and folding of the receiving assembly and the transmitting assembly can be achieved, and installation and use are convenient.

The invention relates to the technical field of biopsy devices, and concretely relates to a safe bone tumor biopsy device. The device comprises a mounting box, a rectangular fixing column is vertically arranged on the surface of the mounting box, a rectangular sliding groove is formed in one side of the rectangular fixing column, a cylindrical mounting bin is formed in the rectangular fixing column, a second spring is arranged in the cylindrical mounting bin, a fixing block is arranged on the other side of the rectangular fixing column and located on the lower middle portion, a locking block is slidably connected to the side face of the fixing block, and a sampling puncture needle body is movably connected to the side face of the rectangular fixing column. The position needing to be sampled is determined through a positioning table, the sampling puncture needle body is inserted into the body of a patient to sample, a pathological specimen can be obtained through a sampling area, a mixture of polyvinyl alcohol and hydrogel in the embolism storage bin is sprayed out from an instantaneous release ring through a micro water pump to timely block a needle hole, and the sampling punctureneedle is thin to avoid the problem of a large incision.

The invention discloses a gastrointestinal tumor biopsy sampling device and belongs to the technical field of medical instrument equipment. The device comprises a lifting assembly, a rotating assembly, a sampling assembly, an expansion assembly, a dirt sucking assembly and a moving assembly, wherein the moving assembly is vertically arranged; the rotating assembly is arranged on the moving assembly and is rotationally connected with the moving assembly; the lifting assembly is arranged at the top of the rotating assembly; the sampling assembly is arranged at the lifting end of the lifting assembly; the sampling assembly comprises a sliding part and two sampling parts; the lifting part is arranged at the lifting end of the lifting assembly; the two sampling parts are symmetrically arrangedat the moving end of the sliding part; the expansion assembly is arranged at the lifting end of the lifting assembly; and the dirt sucking assembly is arranged at the lifting end of the lifting assembly and is positioned at the other end of the sampling assembly. By adopting the device, scraping and sampling operation on a tumor part of a patient is implemented in all direction in multiple anglesthrough swinging of a sampling blade, so that samples of different parts of a tumor of the patient can be obtained.

The invention discloses a medical clinical tumor biopsy sampling device. The sampling device includes a pedestal; each of the four corners at the bottom of the pedestal is provided with a universal wheel having a locking function; the top of the pedestal is connected to the lower end of a first electric push rod; the upper end of the first electric push rod is connected to the bottom of a horizontal plate; a second electric push rod is arranged at the upper part of the horizontal plate; the second electric push rod is connected to a movable plate; the top of the horizontal plate is provided with a disinfection basin; the bottom of the movable plate is provided with a puncture needle; the upper end of the puncture needle is connected to one end of a delivery tube, and the other end of the delivery tube is connected to the liquid inlet of a micro-pump; the liquid outlet of the micro-pump is provided with a collection bag; the micro-pump is arranged on the movable plate; the horizontal plate is provided with a cutting device; and a clamping device is arranged at the bottom of the horizontal plate. Through the cutting device, the needle head of the puncture needle can be cut off and collected, so that virus infection can be avoided; the sampling device can soak aseptic cotton, so that the location where the puncture needle pierces a patient can be disinfected, and the blood of thepatient at the periphery of the puncture needle can be cleaned when the puncture needle is withdrawn; and the sampling device can realize the disinfection of the puncture needle and the delivery tube.

Ex vivo determination of increased tumor immunogenicity of a tumor biopsy is used as a guide to identify immunotherapy of a tumor in a patient. Most preferably, the ex vivo tests will include exposureof biopsy samples to stress conditions to produce pretreated tumor cells that are then assayed with immune competent cells for increased activation or activity. Test conditions include exposure of the biopsy samples to immune stimulatory compositions, antibodies against neoepitopes, and / or modified cells, and an increase of immunogenicity is preferably determined by their exposure to T cells and / or NK cells.

The invention discloses a tumor biopsy penetrator and belongs to the field of medical apparatuses. The tumor biopsy penetrator comprises a medical liquid cylinder body, an outer knife cylinder body and an inner knife cylinder body which sleeve each other from outside to inside, the work ends of the outer knife cylinder body and the inner knife cylinder body are provided with a hook knife and a cutter respectively, and an annular airbag is arranged on the inner wall of the medical liquid cylinder body at the work end; a medical liquid cavity is formed in the medical liquid cylinder body, the medical liquid cavity is communicated with a medicine injection opening, the medical liquid cylinder body is also internally provided with a pushing and injection piston, and the outer knife cylinder body is internally provided with a conductive member connected with an electric interface; a cutter receiving groove and a sampling cavity are formed in the inner knife cylinder body, the cutter receiving groove is rotatably connected to the cutter, a steel wire rope is fixed to the tail end of the cutter, a convex flange is arranged on the side of the cutter, the sampling cavity is communicated with the cutter receiving groove through a bar-shaped hole 2 in the top of the sampling cavity, and the shape of the bar-shaped hole 2 is matched with that of the flange. The tumor biopsy penetrator canprevent proliferation of tumor cells and prevent cross infection, has higher safety, does not cause damage to healthy cells, and achieves drug intervention treatment.

The invention discloses a device for preventing tumor spread after bone tumor biopsy. The device of the invention comprises an operation tube, a connecting tube, a blocking rod and a puncture tube, wherein the puncture tube is in threaded connection below the operation tube; the connecting tube is arranged between a blocking tube and the operation tube; and the puncture tube is used for puncturingtumor tissues, and a biopsy needle extends from the upper end of the blocking rod for sampling during biopsy. Since various parts are tightly connected and tumors can be blocked in all direction, thedevice for preventing tumor spread after bone tumor biopsy has a good anti-spread effect.

The invention discloses a device for preventing tumor diffusion after bone tumor biopsy. The device comprises a base, wherein a plugging plunger is arranged at a front end of the base, an expansion-type plugging assembly is arranged at a front end of the plugging plunger, and a pushing trigger mechanism is arranged at a rear side of the base corresponding to the expansion-type plugging assembly; the expansion-type plugging assembly comprises an expansion pipe arranged at the front end of the plugging plunger, the expansion pipe is superposed with and communicated with an axis of the plugging plunger, and longitudinal grooves are uniformly formed in a peripheral side wall of the expansion pipe; a plunger hole channel is arranged in the plugging plunger; a high-pressure air bag is filled inthe plunger hole channel of the plugging plunger; and the pushing trigger mechanism on the base can push the high-pressure air bag into the expansion pipe. During working, the plugging plunger is installed on a pinhole or a hole channel left after bone tumor biopsy and used for plugging the pinhole or the hole channel, the expansion-type plugging assembly at the front end of the plugging plunger generates an expansion effect to expand and seal the front end of the plugging plunger, thus the sealing effect at the front end of the plugging plunger is greatly improved, and tumor diffusion can beeffectively prevented.

The invention provides a biopsy sampler for a digestive tract tumor, belonging to the technical field of medical instruments. The biopsy sampler for the digestive tract tumor comprises a placing plate, wherein the upper surface of the placing plate is provided with a display device and an inflation device, the lower surface of the placing plate is fixedly connected with an outer tube, the outer tube is internally provided with a connecting steel wire and a ventilation tube, the ventilation tube is internally provided with a cable conductor, one end of the connecting steel wire is fixedly connected with a pull ring, and the other end of the connecting steel wire is fixedly connected with a connecting base. Under the action of an inner support frame, an ellipsoidal air bag is greatly deformed at an elastic bag, so a sampling blade drives the fine hair of insoluble dietary fiber to move out of a sampling groove so as to clean dirt on the surface of the tumor, and then a soluble dietary fiber adhesion layer is dissolved, so the fine hair of the insoluble dietary fiber is separated and enters a digestive tract; after the ellipsoidal air bag is deflated, the elastic bag retracts, the sampling blade cuts the tumor and brings the tumor into the elastic bag, and then the tumor can be taken out after inflation.

The invention relates to the field of medical technology, in particular to a special sampler for digestive tract tumor biopsy tissue, which includes a catheter, a sampling box, a sampling mechanism and a pair of clamping knives. The sampling box is arranged on the catheter head through two rotating shafts. The cylindrical surface is provided with a sampling port, the head of the sampling box fits the sampling port on the conduit, two rotating shafts pass through the sampling box and are inserted at both ends of the sampling port in the length direction, and a pair of clamping knives are symmetrically arranged on the head of the sampling box The tail of each clamping knife can be rotatably sleeved on the rotating shaft at the corresponding position, and the sampling mechanism is arranged in the sampling box and the conduit. The invention has simple structure and convenient operation. Each structure is located in the catheter or adheres to the outer wall of the catheter, which will not cause damage to the digestive tract. When sampling, the sampled tissue is cut and clamped by a clamp knife so that the sampled tissue is not easy to fall and lose.

The invention relates to a safe tumor biopsy apparatus system less likely to cause bleeding. The system is provided with a cystoscopy and an extractor; the cystoscopy is provided with a cystoscopy tube, an eye lens, a cold light source interface and a negative pressure connecting tube, and the inside of the cystoscopy tube is provides with an apparatus channel, an observation channel and a drainage channel; the extractor is provided with a parent cylinder, a daughter cylinder, a negative pressure attraction sphere and a sleeving component, the daughter cylinder is connected to the inside of the parent cylinder in a sleeving mode, the parent cylinder and the daughter cylinder can relatively freely slide, the negative pressure attraction sphere is arranged at the near end of the daughter cylinder, and the sleeving component is used for sleeving tumors which are attracted inside the far end of the daughter cylinder through the negative pressure attraction sphere along the outside of the daughter cylinder; in a work state, the extractor arrives at a focal part through the apparatus channel. The safe tumor biopsy apparatus system is not likely to cause bleeding after biospy, and is easy to study and easy to operate, minimally invasive, fast in postoperative recovery, simple in structure, low in cost and particularly suitable for biopsy of bladder neoplasms.