34 results about "Tarsal Glands" patented technology

A device for stimulating the meibomian glands of the eyelid comprising: a handle; a head that is non-removable and integral to the handle, the head comprising an eyepiece that oscillates to provide a massaging action to an eyelid and that comprises a front end that is concave in shape to fit over an eyelid; a heater located inside of the eyepiece; a temperature sensor located inside of the eyepiece, wherein the temperature sensor causes the eyepiece to heat to a predetermined temperature and then stop heating; and a charging base that supplies power to a motor that causes the eyepiece to oscillate, wherein the motor comprises a motor shaft. A method of applying heat and massaging action to the eyelid at the same time.

The invention relates to a comprehensive ocular surface analyzer based on an expert system. The comprehensive ocular surface analyzer comprises a comprehensive ocular surface analyzer hardware module, an image processing module and an expert system module, wherein the comprehensive ocular surface analyzer hardware module comprises a controller, a structured illumination module and an imaging module; the image processing module comprises a tear meniscus height measuring module, a red eye detection module, a tear film stability detection module, a meibomian gland morphology detection module and a corneal topography analysis module; and the expert system takes information acquired though image processing as the input, performs objective and correct judgment on common diseases of the human ocular surface and provides therapeutic measures.

An occular image of a region including meibomian glands is processed automatically. The processing may derive a grade indicative of the health of the meibomian glands, by using in the occular image to obtain one or more numerical parameters characterizing the meibomian glands shown in the occular image, and determining the grade using the one or more numerical parameters. The numerical parameters include a parameter characterizing the diversity between scale parameters of significant features of the image obtained by a scale-space transform, and / or parameters obtained by measurement of lines in the occular image representing respective glands. Meibomian glands can be identified on ocular images using Gabor filtering as a local filtering technique. The parametrization in shape, local spatial support, and orientation of Gabor filtering is particularly suitable for detecting meibomian glands.

A combined eyelid warming device, resonance frequency generator, coupling device, and tissue response sensor are disclosed in the field of use in dry eye treatment. These combined devices are used to ensure that the entire eyelid surface and periorbital structures receive defined therapeutic warmth and appropriately tuned harmonic resonance frequency for a required period of time to stimulate flow from the Meibomian glands. The combined elements of the invention include an easily moldable heating disc, targeted formulation of the heating material, miniaturized resonant frequency vibrating generator combined with a properly designed reusable mask, to ensure precise location of the heat. Vibration may be delivered continuously or intermittently, and may be delivered according to one or more patterns. A chemical sensor is included to characterize flow as vibration is varied. The external energy source allows for circuitry in the external power module to act as a sweep range device, targeting the specific optimally tuned point or sweep frequency the individual patients body reacts to during initial use. The initial testing device supplied to the Doctor for treatment would include sensing elements to determine the optimal harmonic resonance frequency. Once the frequency is defined, the patient would receive a kit with custom harmonic resonant frequency vibrating generators set to their optimum parameters. This configuration would be amenable to both single use and reusable heater approaches.

A device for stimulating the meibomian glands of the eyelid comprising: a handle; a head that is non-removable and integral to the handle, the head comprising an eyepiece that oscillates to provide a massaging action to an eyelid and that comprises a front end that is concave in shape to fit over an eyelid; a heater located inside of the eyepiece; a temperature sensor located inside of the eyepiece, wherein the temperature sensor causes the eyepiece to heat to a predetermined temperature and then stop heating; and a charging base that supplies power to a motor that causes the eyepiece to oscillate, wherein the motor comprises a motor shaft. A method of applying heat and massaging action to the eyelid at the same time.

The invention discloses a comprehensive analysis system for xerophthalmia. The comprehensive analysis system comprises an imaging system, an analyzing system and a video terminal, wherein the imaging system comprises a lighting source, an imaging assembly, a control panel and a camera shooting module, the lighting source penetrates through the imaging assembly and irradiates the eyes of a patient, and the camera shooting module carries out imaging on the eyes of the patient, and transmits the generated image to a PC machine through a USB interface; the analyzing system is arranged at the PC machine end, and comprises a communication module, an image data collecting module, a tear film breakup time check module, a lacrimal rivus height measuring module, a meibomian gland image collecting and enhancing module, a lipid layer analyzing module, a data analyzing module and an information management output module; the video terminal is connected with the analyzing system. With the comprehensive analysis system for xerophthalmia provided by the invention, the functions of tear film breakup time statistics checking, lacrimal rivus height measurement, meibomian gland image collection and enhancement, human eye lipid layer analysis, and the like are realized, a basis is provided for the clinical diagnosis for xerophthalmia, and the comprehensive analysis system is applied to the medical treatment in the relevant fields of clinical diagnosis of the ophtalmology department.

The invention provides an eyelid massager which comprises a binding part used for being bound with the head of a user, a fixing part arranged at the front end of the binding part, a driving part installed on the fixing part in a rotation mode, a massaging part arranged by corresponding to the eyes, connected with the driving part and used for massaging the eyes under the drive of the driving part and a switch used for starting or stopping the driving part. The massaging part comprises upper eyelid massaging balls corresponding to the upper eyelids of the eyes and lower eyelid massaging balls corresponding to the lower eyelids of the eyes. The driving part is used for driving the upper eyelid massaging balls to extrude and massage the upper eyelids from top to bottom repeatedly and at the same time, driving the lower eyelid massaging balls to extrude and massage the lower eyelids from bottom to top repeatedly. The upper eyelids and the lower eyelids of the user are massaged specifically. The manner of increasing the pressure is used for discharging thick and dense secreta in the meibomian glands so as to eliminate jamming of the meibomian glands and achieve the aim of promoting smooth secretion of the meibomian glands.

The invention provides a meibomian gland massaging device which comprises a massaging device body, a sliding block (6) and a driving mechanism, wherein the massaging device body comprises an upper clamping plate (1) and a lower clamping plate (2), the lower clamping plate (2) is provided with a gasket (22), the sliding block (6) is arranged in the massaging device body and can slide, the extruded surface of the sliding block (6) is arranged opposite to the supporting surface of the gasket (22), and the driving mechanism is connected with the sliding block (6) and drives the sliding block (6) to slide. Compared with the prior art that a doctor needs to turn the eyelid of a patient outside by one hand and massage the meibomian gland by the other hand with a cotton stick, the meibomian gland massaging device provided by the invention can be operated by one hand without turning the eyelid of the patient outside in the meibomian gland massaging process, is simple to operate, reduces the difficulty in massage of meibomian gland of the patient, and improves the safety and the effectiveness of meibomian gland massage.

The invention discloses a dot-matrix meibomian gland dysfunction treatment device which comprises a lining plate, an outer extruder and a controller, wherein the lining plate is provided with a connecting plate; the outer extruder is arranged on the connecting plate; a gap is reserved between the outer extruder and the lining plate; the outer extruder comprises multiple extrusion columns; a drive mechanism is arranged behind each extrusion column; and the drive mechanism is connected with the controller and drives the extrusion columns to realize reciprocating motion. The device disclosed by the invention realizes no-leakage point knock on meibomian gland and can comprehensively extrude the eyelid; and moreover, each extrusion column knocks the meibomian gland so that the meibomian gland vibrates and the obstruction of the meibomian gland is dredged.

An occular image of a region including meibomian glands is processed automatically. The processing may derive a grade indicative of the health of the meibomian glands, by using in the occular image to obtain one or more numerical parameters characterizing the meibomian glands shown in the occular image, and determining the grade using the one or more numerical parameters. The numerical parameters include a parameter characterizing the diversity between scale parameters of significant features of the image obtained by a scale-space transform, and / or parameters obtained by measurement of lines in the occular image representing respective glands. Meibomian glands can be identified on ocular images using Gabor filtering as a local filtering technique. The parametrization in shape, local spatial support, and orientation of Gabor filtering is particularly suitable for detecting meibomian glands.

The invention provides an efficient eye therapeutic apparatus. The efficient eye therapeutic apparatus comprises a shell, a fixing belt, a right massage mechanism, a left massage mechanism, a connecting belt, a right elastic belt, a left elastic belt and two fog guide channels, wherein the fixing belt is connected with two ends of the shell, the right massage mechanism and the left massage mechanism are positioned at the inner side of the shell, each of the right massage mechanism and the left massage mechanism is connected with the shell through one fog guide channel, the right massage mechanism and the left massage mechanism are connected through the connecting belt, the right massage mechanism is connected with the shell through the right elastic belt, the left massage mechanism is connected with the shell through the left elastic belt, and a control button is arranged on the shell. The efficient eye therapeutic apparatus is provided with a heating board, vibrators and an atomizer, the functions of hot compress, meibomian glands massage and aerosol fumigation can be carried out respectively, through the combined action of the heating board, the vibrators and the atomizer, the dry eye disease can be alleviated and treated.

Described methods and compositions for treating Meibomian Gland Disease (MGD) for normalizing gland secretions and improving symptoms of ocular surface diseases associated with MGD. The methods concern treatment of a patient with aldosterone antagonists, such as spironolactone or analogues of spironolactone. Spironolactone is desirably added in a novel treatment composition, preferably in the form of an aqueous solution, emulsion or suspension in small but effective concentrations and in a novel vehicle that adds to the increased solubility of what previously was known to be an insoluble active agent. Moreover, it is believed that the specific lower but effective concentrations of spironolactone, and / or the pluronic vehicle of the treatment composition, permits optimal expression of essential lipids and upregulation of genes that control lipid production necessary to a more normalized lipid component of the tear film for the treatment and / or the prevention of signs and / or symptoms of MGD.

A disposable / removable tip attachable on a distal end of a fiber bundle, allowing transmitting light energy from the fiber bundle to an eyelid and comprising a contact surface made of bio-compatible material, which allows to contact the eyelid and in addition an add-on device, comprising a fiber bundle, having a distal and proximal end, wherein a disposable / removable tip is attachable to the distal end, while the proximal end is connected to an optical coupler, designed for optical and / or energy coupling with a lightguide of a Meibomian gland expression (MGX) treatment device.

Forceps treatment systems are described in which a forceps apparatus may generally comprise a first handle and a second handle coupled to one another near or at respective proximal ends. A first paddle may be coupled to the first handle and define a first inner surface, a second paddle may be coupled to the second handle and define a second inner surface which is positioned in apposition to the first inner surface. Furthermore, a debriding member may extend proximally from the first and second handles and reduce and curve gently to define a debriding edge for debriding tissue in proximity to one or more meibomian glands. The forceps apparatus may be used in combination with a heat treatment for treating one or more meibomian glands in a subject.

A compound represented by the formula (1):wherein R1 represents a hydroxyl group, a dimethylphosphynoyloxy group, etc.; and R2 and R3 represent a methoxy group, etc.,or a pharmaceutically acceptable salt thereof can reduce a score of telangiectasia around the meibomian gland orifices and a number of obstruction at the orifices, so that it is useful as a prophylactic and / or therapeutic agent for meibomian gland dysfunction.

The invention discloses a meibomian gland massaging instrument. The meibomian gland massaging instrument is characterized in that two massaging roller sets of symmetrical structures are installed at the two ends of a multi-head worm and gear set on the back vertical wall of a central motor box, three rotating shafts are fixed to a motor through worm-wheel shafts, and the axes of a pair of upper and lower rollers of each massaging roller set are parallel; gears at the opposite axis ends of the two lower massaging rollers and gears at the ends of the upper massaging rollers are meshed to form avertical column structure through a pair of transmission gears, and each set of massaging rollers oppositely rotate inward; the opposite axis ends of the two lower massaging rollers are perpendicularly fixed through two parallel and vertical hanging rods, parallel supporting pipes are further arranged on the outer sides of the hanging rods to prevent the hanging rods from moving horizontally, andwires are arranged in the supporting pipes. An operation panel is arranged on a Bluetooth remote control device, a Bluetooth wireless communication module and control and heating circuits are arrangedin the operation panel, and a heating control module is provided with two current collecting rings and a rotating shaft, namely, a rotating heating bar; in order to treat the meibomian gland dysfunction, massaging and hot compress can be conducted synchronously, and massaging and hot compress can be conducted separately. A patient can use the meibomian gland massaging instrument conveniently.

The invention discloses a meibomian gland infrared image auxiliary recognition system and method based on deep learning. The meibomian gland infrared image auxiliary recognition system comprises a client, a server and a database. The client is used for uploading the meibomian gland image acquired by the infrared camera equipment to the server, and receiving and displaying an analysis result fed back by the server; The server is used for immediately judging a part corresponding to the image and a part feature according to the image acquired from the client and feeding an analysis result back tothe client; And the database is used for storing the images acquired by the infrared camera equipment and the analysis result fed back by the server. The collected meibomian gland images are identified in real time through the convolutional neural network model, the portions and the portion features are identified, real-time prompting is carried out on the image display system, accurate and reliable reference is provided for doctors, the detection accuracy and effectiveness are improved, the method is simple and easy to use, and remarkable social and economic values are achieved.

Described here are devices, systems, and methods for treating meibomian gland disease and / or blepharitis by providing intranasal stimulation. Generally, the devices may deliver electrical stimulation to the nasal mucosa. Intranasal stimulation may unblock obstructed meibomian glands and increase the lipid content of tears, both acutely during stimulation and subsequent to intranasal stimulation. The methods may include an initial round of stimulation to unblock obstructed meibomian glands, and subsequent shorter rounds of stimulation to cause meibum secretion and maintain the open glands.

The invention discloses a visual meibomian gland massage system. The massage system comprises a massage part and a head mounted display part; the massage part comprises a cavity shell, a protection shell, a small light source device and a small camera shooting device are arranged on the top of the cavity shell, a lower massage piece installation rod is fixedly arranged on the outer side of the protection shell, a lower massage piece is installed at the end of the lower massage piece installation rod, and a pulling rod, a right angle rod, an extension spring and a traction rope are arranged at the upper end inside the cavity shell; the horizontal section of the right angle rod is located on the upper portion of the lower massage piece installation rod and protrudes out of the cavity shell, an upper massage piece is connected to the horizontal section, the meibomian gland is subjected to extrusion massage through the upper massage piece and the lower massage piece, and the driving mode is simple and reliable.

The invention discloses a dry eye treatment instrument. The instrument comprises a casing (1), a bracket (2), a pair of eye mask bodies (3) capable of fitting the eye sockets of the human body and made of a flexible material, a heating assembly and a vibration assembly; the casing (1) is installed on the bracket (2), the eye mask bodies (3) are arranged on the bracket (2), the bracket (2) is provided with two first through holes (2.1), and the eye mask bodies (3) are provided with second through holes (3.1) corresponding to the first through holes (2.1) respectively; the instrument is characterized in that each eye mask body (3) is provided with a flange structure extending toward the center, and a bent supporting part of each flange structure is a part, fitting the corresponding eye socket of the human body, of the corresponding eye mask body (3). By means of the dry eye treatment instrument, hot compress and massage vibration on the meibomian glands are conducted synchronously, the effects are good, the same part is adopted, the requirements of the eye sockets of different human bodies can be better met, the eyeballs are not squeezed, and the structure is compact.

The invention discloses a meibomian gland heating massage fingerstall. The fingerstall is used for heating and massaging the meibomian gland. The fingerstall comprises a fingerstall body, a heating component, a switching module and power source. An interlayer is arranged inside the fingerstall. The heating component is arranged inside the interlayer, the heating component is connected with the switching module, and the switching module is connected with the power source. After the power source is turned on, the switching module can be powered on, the heating component is opened or closed, thetemperature of the heating component can be regulated, and the meibomian gland can be heated and massaged when the fingerstall is put on. According to the meibomian gland heating massage fingerstall,the fingerstall is heated, the hot compressing effect is achieved, it is ensured that manual massage force is suitable, operation is easy, use is convenient, the fingerstall is not affected by terrains, materials and other factors, the economic cost is saved, and the massage quality is ensured.

The invention provides an eyelid massage spectacles which comprises a spectacle frame, a massage part, a driving component for driving the massage part to move, and a switch for starting or stopping the running of the driving component, wherein the driving component is arranged on the spectacle frame; the massage part comprises an upper eyelid massager corresponding to an upper eyelid and a lower eyelid massager corresponding to a lower eyelid; the upper eyelid massager is driven to move from top to bottom by the driving component while the lower eyelid massager is driven to move from bottom to top by the driving component; a pressure-boosting mode is utilized to discharge the stiff excreta from the meibomian glands, so that the block of the meibomian glands is eliminated and the purpose of promoting the smooth secretion of the meibomian glands is achieved.

Forceps treatment systems are described in which a forceps apparatus may generally comprise a first handle and a second handle coupled to one another near or at respective proximal ends. A first paddle may be coupled to the first handle and define a first inner surface, a second paddle may be coupled to the second handle and define a second inner surface which is positioned in apposition to the first inner surface. Furthermore, a debriding member may extend proximally from the first and second handles and reduce and curve gently to define a debriding edge for debriding tissue in proximity to one or more meibomian glands. The forceps apparatus may be used in combination with a heat treatment for treating one or more meibomian glands in a subject.

The invention discloses a dot-matrix meibomian gland dysfunction treatment device which comprises a lining plate, an outer extruder and a controller, wherein the lining plate is provided with a connecting plate; the outer extruder is arranged on the connecting plate; a gap is reserved between the outer extruder and the lining plate; the outer extruder comprises multiple extrusion columns; a drive mechanism is arranged behind each extrusion column; and the drive mechanism is connected with the controller and drives the extrusion columns to realize reciprocating motion. The device disclosed by the invention realizes no-leakage point knock on meibomian gland and can comprehensively extrude the eyelid; and moreover, each extrusion column knocks the meibomian gland so that the meibomian gland vibrates and the obstruction of the meibomian gland is dredged.

The embodiment of the invention discloses an ion negative-pressure fatting pouch-eliminating method and device. A 'three-dimensional digital imaging technology' is applied to clearly display the distribution state of orbital septum adipose tissues, a thermal effect dissolving principle is applied to liquefy and dissolve excessive fat in the orbital septum according to the condition of fat herniation, liquefied fat is discharged out of the body through the meibomian glands by means of an ion negative-pressure technology, and meanwhile an orbital septum supporting structure is strengthened. Theflabby infraorbital tissues are integrally lifted, the normal physiological function of the lower eyelids is restored, the skin of the lower eyelids cannot be flabby while orbital fat is removed, accordingly pouches are eliminated, and the pouch problem is thoroughly solved.

The invention discloses a device for delivering medicine to the meibomian glands, which includes a handle, a treatment head, and a meibomian gland drug delivery patch. A control system is installed in the handle, and the treatment head is detachably connected to the meibomian gland. On the upper end of the handle, an electromagnet is arranged in the treatment head, and the meibomian gland drug delivery patch is magnetically connected with the treatment head through the electromagnet, and the meibomian gland drug delivery patch is provided on the left side. There is a microneedle drug delivery component, the drug layer is arranged inside the microneedle drug delivery component, and the electromagnetic control module of the control system intermittently controls the power on and off of the electromagnet to drive the treatment head and the meibomian gland The dosing patch is intermittently clamped and released on the patient's upper and lower eyelids. The invention has the advantages of fast and efficient administration, comfort and convenience, reasonable design, good therapeutic effect, safe and painless drug delivery, and the like.

Provided herein are pharmaceutical compositions comprising a therapeutically effective amount of a lipophilic compound and a pharmaceutically acceptable carrier adapted for peri-ocular transdermal delivery of the lipophilic compound to one or more periorbital glands and / or the ocular surface tissues of a subject. Further provided herein are methods of using such pharmaceutical compositions for providing relief of one or more signs or symptoms of an ocular disease, methods of using one or more Meibomian glands (and meibum therein) as a drug delivery system for a lipophilic compound (e.g., a steroid) to the ocular surface, and kits related thereto.

The invention relates to a meibomian gland heating and fumigating device for xerophthalmias. The meibomian gland heating and fumigating device comprises a wearable assembly, a temperature control assembly and a medicine assembly. The meibomian gland heating and fumigating device is simple in operation, the temperature is controllable in a meibomian gland hot compressing process, and the guarantee of controlling the skin around eyes at a relatively appropriate temperature in a working process is realized, so that the problems that an existing physical hot compressing method is great in temperature fluctuation and the hot compressing time and temperature are difficult to control are avoided, and the hot compressing effect is improved. Heating power generated by infrared rays can permeate through the deep layer of the skin, so that the blood circulation is quickened; the operating temperature of an infrared heating plate is controlled at 38-42 DEG C; the therapy of the infrared heating plate is a non-invasive therapy, safe and convenient, and is free of toxic and side effects; the heating temperature and time can be individually selected according to the conditions of each patient. Meanwhile, the device provided by the invention contains traditional Chinese medicine fumigation; medicine absorption and availability can be promoted while pipes of meibomian glands are open; the device is suitable for different types of xerophthalmias, and the therapeutic safety and effectiveness for the xerophthalmias are improved.