1058 results about "Tear production" patented technology

Unitary surgical devices (10) are disclosed. One group of the illustrated devices has a pair of biocompatible, bioresorbable anchors (16,18) connected to fixed lengths suture. The anchors (16,18) and fixed length of suture are connected to each other prior to surgery. Another group of unitary surgical devices has a pair of fixating mechanisms (15,17) connected to a base (21) prior to surgery. The second group of illustrated devices generally includes extracellular matrix material either as part of the base (21) or supported on the base (21). The extracellular matrix material serves as tissue regenerating material. In the second group of unitary surgical devices, the fixating mechanisms illustrated generally comprise suture, anchors or pre-formed holes in the base. All of the illustrated unitary surgical devices are useful in repairing a damaged meniscus. The first group of unitary surgical devices can be used to approximate inner surfaces of a tear in the meniscus. The second group of devices can be used either as an insert to be placed between and approximated to the inner surfaces of the tear or as an insert to replace a void in the meniscus left after a meniscectomy.

The present invention relates to endoscopic clips with multiple independently-controlled legs. The present invention also relates to a method for using a clip with multiple independently actuated legs. The clips and methods of the present invention may be used, for example and without limitation, for repairing tears and other defects endoscopically.

A chain of loops of braided high strength suture for surgical applications. The suture chain is advantageous for use in knotless fixation of soft tissue to bone, and can be used for knotless side-to-side suturing of U-shaped defects, such as rotator cuff tears.

An implant for insertion into a punctum of a patient comprises a body. The body has a distal end, a proximal end, and an axis therebetween. The distal end of the body is insertable distally through the punctum into the canalicular lumen. The body comprises a therapeutic agent included within an agent matrix drug core. Exposure of the agent matrix to the tear fluid effects an effective therapeutic agent release into the tear fluid over a sustained period. The body has a sheath disposed over the agent matrix to inhibit release of the agent away from the proximal end. The body also has an outer surface configured to engage luminal wall tissues so as to inhibit expulsion when disposed therein. In specific embodiments, the agent matrix comprises a non-bioabsorbable polymer, for example silicone in a non-homogenous mixture with the agent.

An ophthalmic lens suited for extended-wear periods of at least one day on the eye without a clinically significant amount of corneal swelling and without substantial wearer discomfort. The lens has a balance of oxygen permeability and ion or water permeability, with the ion or water permeability being sufficient to provide good on-eye movement, such that a good tear exchange occurs between the lens and the eye. A preferred lens is a copolymerization product of a oxyperm macromer and an ionoperm monomer. The invention encompasses extended wear contact lenses, which include a core having oxygen transmission and ion transmission pathways extending from the inner surface to the outer surface.

Utilization of a contact device placed on the eye in order to detect physical and chemical parameters of the body as well as the non-invasive delivery of compounds according to these physical and chemical parameters, with signals being transmitted continuously as electromagnetic waves, radio waves, infrared and the like. One of the parameters to be detected includes non-invasive blood analysis utilizing chemical changes and chemical products that are found in the conjunctiva and in the tear film. A transensor mounted in the contact device laying on the cornea or the surface of the eye is capable of evaluating and measuring physical and chemical parameters in the eye including non-invasive blood analysis. The system utilizes eye lid motion and / or closure of the eye lid to activate a microminiature radio frequency sensitive transensor mounted in the contact device. The signal can be communicated by wires or radio telemetered to an externally placed receiver. The signal can then be processed, analyzed and stored. Several parameters can be detected including a complete non-invasive analysis of blood components, measurement of systemic and ocular blood flow, measurement of heart rate and respiratory rate, tracking operations, detection of ovulation, detection of radiation and drug effects, diagnosis of ocular and systemic disorders and the like.

An improved corneal contact lens for use in orthokeratology wherein the lens has an anterior surface, posterior surface and includes a tear zone which defines a tear reservoir located on the posterior surface of the lens. The improvement involves providing at least one fenestration surface located in the tear zone which defines an opening extending through the contact lens from the anterior surface to the posterior surface. The openings in the tear zone relieve fluid pressure which was found to cause certain symptoms, such as lens adhesion, tightening and general wearing discomfort. The fenestrations in the tear zone provide enhanced wearing comfort without adversely affecting the cornea-shaping properties of the lens.

This invention provides articles and methods for drug delivery including a hydrogel containing one or more drugs for the treatment of a posterior segment disease and / or dry eye conditions. Exemplary drugs are anti-angiogenesis compounds for the treatment of macular degeneration. Allowing passive transference of this drug from a dilute solution into the hydrogel produces the delivery system. The hydrogel, when placed in contact with the eye, delivers the drug. The delivery of the drug is sustained over an extended period of time, which is of particular utility in the eye, which is periodically flushed with tears. This sustained delivery accelerates the treatment process while avoiding potential damaging effects of localized delivery of high concentrations of compounds, e.g., from eye drops.

A method and apparatus are provided by which eyelid diseases may be treated and eyelid hygiene may be performed. In particular, the method and apparatus stimulate eyelid muscles and facial muscles, allowing stimulation of glandular eyelid components that allow optimization of the tear film and the ocular surface. In this manner, the symptoms associated with ocular irritation or with eyelid disorders may be treated by maintaining proper tear film composition.

The present invention is directed to a pliable package that is tear resistant, requires a greater degree of dexterity to open, and prevents accidental discharge during or after opening of the package. The package includes a flexible, liquid storage reservoir having a funnel-shaped outlet passageway leading to a opening. The package also includes a reinforced tear resistant tab portion that may prevent accidental discharge of liquid when the tab portion is bent about the score line. The funnel-shaped outlet passageway may be shaped to allow the liquid to be dispensed in a controlled manner.

A method and apparatus are provided by which eyelid diseases may be treated and eyelid hygiene may be performed. In particular, the method and apparatus stimulate eyelid muscles and facial muscles, allowing stimulation of glandular eyelid components that allow optimization of the tear film and the ocular surface. In this manner, the symptoms associated with ocular irritation or with eyelid disorders may be treated by maintaining proper tear film composition.

An ophthalmic lens suited for extended-wear periods of at least one day on the eye without a clinically significant amount of corneal swelling and without substantial wearer discomfort. The lens has a balance of oxygen permeability and ion or water permeability, with the ion or water permeability being sufficient to provide good on-eye movement, such that a good tear exchange occurs between the lens and the eye. A preferred lens is a copolymerization product of a oxyperm macromer and an ionoperm monomer. The invention encompasses extended wear contact lenses, which include a core having oxygen transmission and ion transmission pathways extending from the inner surface to the outer surface.