94 results about "Orthokeratology" patented technology

An improved corneal contact lens for use in orthokeratology wherein the lens has an anterior surface, posterior surface and includes a tear zone which defines a tear reservoir located on the posterior surface of the lens. The improvement involves providing at least one fenestration surface located in the tear zone which defines an opening extending through the contact lens from the anterior surface to the posterior surface. The openings in the tear zone relieve fluid pressure which was found to cause certain symptoms, such as lens adhesion, tightening and general wearing discomfort. The fenestrations in the tear zone provide enhanced wearing comfort without adversely affecting the cornea-shaping properties of the lens.

Two types of compositions having an eye-drop delivery system are used during or after an orthokeratology procedure to prevent or retard relaxation of corneal tissue back to the original anterior curvature of the cornea. Each composition functions independently from the others and is a different approach of preparing a stabilizing agent. The first composition is directed to a biologically compatible composition comprising fibril associated collagens with interrupted triple helices (FACITs) and / or small leucine-rich repeat proteoglycans (SLRPs). The fibril associated collagen family includes various types of collagens, such as type VI, type XX, type XII, and type XIV. The small leucine-rich repeat proteoglycans family includes decorin, keratocan, biglycan, epiphycan, lumican, mimecan, and fibromodulin. The second composition includes the enzyme found as a normal component of tissues, plasma, or epidermis, such as transglutaminase.

This invention relates to methods of shaping the anterior surface of the eye for controlling the progression of refractive error of the eye, in particular, myopia. The method employs the fitting of orthokeratology lenses having a precisely shaped posterior surface adapted to accurately shape the peripheral region of the eye. The method includes the steps of assessing central and peripheral refractive error parameters for the eye, determining the optimal anterior surface profile for the eye, including at both the optical centre of the cornea and at a selected optical periphery of the cornea, which would result in a desired refractive correction to achieve good vision for the eye and the desired peripheral refraction (curvature of field) for the eye for controlling progression of myopia. Accurate measurement of the shape of the pre-treated eye is important, thereby enabling a corresponding lens profile to be designed or selected so that the treatment process achieves a post-treatment peripheral profile which optimally focuses peripheral rays anteriorly of the retina, thereby controlling the progression of myopia. The invention extends to a lens manufactured so as to optimally treat the peripheral region of the eye.

A contact lens is fitted to a cornea of a patient's eye to gradually alter the patient's cornea during continued wear to reshape the cornea to reduce the hyperopia and / or presbyopia condition. The contact lens has a plurality of zones that includes one or two optical zones, a plateau zone, a fitting zone, an alignment zone and a peripheral zone. The one or more optical zones are utilized to redistribute cornea tissue to cause the cornea to have a steepened central portion surrounded by a flat mid-peripheral ring The plateau zone helps steepening the central cornea by two ways: a positive molding effect of pushing the cornea tissue inward to pile up and a negative molding effect to flatten the mid-peripheral cornea for enhancing.

Lenses are designed using the corneal topography or wavefront measurements of the eye derived by subtracting the optical power of the eye after orthokeratology treatment from the optical power before orthokeratology treatment.

Lenses are designed using the corneal topography or wavefront measurements of the eye derived by subtracting the optical power of the eye after orthokeratology treatment from the optical power before orthokeratology treatment.

A contact lens is fitted to a cornea of a patient's eye to gradually alter the patient's cornea during continued wear to reshape the cornea to reduce the hyperopia and / or presbyopia condition. The contact lens has a plurality of zones that includes one or two optical zones, a plateau zone, a fitting zone, an alignment zone and a peripheral zone. The one or more optical zones are utilized to redistribute cornea tissue to cause the cornea to have a steepened central portion surrounded by a flat mid-peripheral ring The plateau zone helps steepening the central cornea by two ways: a positive molding effect of pushing the cornea tissue inward to pile up and a negative molding effect to flatten the mid-peripheral cornea for enhancing.

Ophthalmic conditions such as presbyopia, myopia, and astigmatism can be corrected by the use of a molding contact lens in combination with a pharmaceutical composition suitable for delivery to the eye. The molding contact lenses are preferably commercially available and are not specifically designed for orthokeratology. The agents in the pharmaceutical compositions such as hyaluronase allow the cornea of the eye to be molded in order to correct the refractive error of the eye. The contact lenses and the pharmaceutical composition induce a change in the radius of curvature of the anterior surface of the cornea, thereby correcting the refractive error of the eye. One advantage of the inventive technique is that the patient with his or her own individual visual needs guides the treatment until the patient near and far visual needs are met. The present invention also provides for kits, which contain molding contact lenses, pharmaceutical composition suitable for delivery to the eye, and instructions, useful in the inventive system.

Lenses are designed using the corneal topography or wavefront measurements of the eye derived by subtracting the optical power of the eye after orthokeratology treatment from the optical power before orthokeratology treatment.

A contact lens for vision correction, comprising a central zone, an alignment zone located concentrically around the central zone, and a bearing zone that is coupled to both the central zone and the alignment zone. The bearing area is configured to directly contact a cornea and prevent both the central zone and alignment zone from directly contacting the cornea

The present invention is directed to a contact lens design and methods of manufacturing, fitting and using such lenses. As an example, the contact lens may be designed to be used in an orthokeratology treatment program. The contact lens according to the invention overcomes the deficiencies of the prior art, and provides a design which allows proper fitting of a patient, whether for corrective contact lenses or for use in an orthokeratology treatment program. The ability to properly fit a patient will alleviate, at least to a great degree, corneal abrasions from poorly distributed bearing, corneal warpage from decentered lenses, edema from tight fitting lenses and discomfort. The design allows a great deal of flexibility to the fitter to enhance the functionality of the lens. The lens of the present invention includes a central zone and first annular zone located adjacent to and concentrically around the central zone. The two zones are integral with each other and the radius of curvature of the first annular or connecting zone is greater than that of the central zone. In addition, such a design provides a vast amount of alternative methods of manufacture, and lifts the constraint of requiring the origin of the radius of curvature for the first annular zone curve to reside on the central axis of the central base curve or zone.

Methods of increasing the permeability of corneal epithelium to facilitate the diffusion of agents into the collagen fibrillar network of the stroma are provided. Used in combination, these methods open the epithelium to facilitate diffusion of stabilization molecules into the stroma and dissociate bridging molecules from stromal collagen fibers, thereby priming the collagen fibrillar network for restabilization by stabilization molecules. These methods can be used to increase the effectiveness and longevity of non-invasive corneal reshaping, such as orthokeratology, for correcting myopia, hyperopia and astigmatism.

Methods of treating a refractive error of the eye are disclosed comprising applying a treatment that induces swelling of the corneal tissue and applying an orthokeratology lens configured to correct the refractive error that provides a controlled distribution of the corneal tissue.

The invention relates to an OCT (Optical Coherence Tomography) imaging system and a measurement method for monitoring the shaping effect of an orthokeratology lens by using a living body, wherein the OCT imaging system comprises a control computer, a spectral-domain OCT imaging module, a human eye scanning module and an optotype aligning module; the spectral-domain OCT imaging module comprises a partial spectral-domain OCT imaging module and a full spectral-domain OCT imaging module; a movable 45-degree spectroscope is arranged between the partial spectral-domain OCT imaging module and the full spectral-domain OCT imaging module. The measurement method comprises the following steps of (1) obtaining a full orthokeratology image of a living body; (2) obtaining an actual lens thickness contour image; (3) analyzing the center positioning state of the whole orthokeratology lens; (4) obtaining a partial high-definition image of the orthokeratology lens, and obtaining the length, width and area of a transition region. According to the OCT imaging system and the measurement method for monitoring the shaping effect of the orthokeratology lens by using the living body, the orthokeratology image of the living body and the partial orthokeratology image in a feature region are analyzed, the transition region of the orthokeratology lens is directly imaged, and a purpose of dynamically monitoring the cornea flattening progress and the cornea shaping effect according to the dynamic variation of a tear film along with time is achieved.

The present invention is directed to a contact lens design and methods of manufacturing, fitting and using such lenses. As an example, the contact lens may be designed to be used in an orthokeratology treatment program. The contact lens according to the invention overcomes the deficiencies of the prior art, and provides a design which allows proper fitting of a patient, whether for corrective contact lenses or for use in an orthokeratology treatment program. The ability to properly fit a patient will alleviate, at least to a great degree, corneal abrasions from poorly distributed bearing, corneal warpage from decentered lenses, edema from tight fitting lenses and discomfort. The design allows a great deal of flexibility to the fitter to enhance the functionality of the lens. The lens of the present invention includes a central zone and first annular zone located adjacent to and concentrically around the central zone. The two zones are integral with each other and the radius of curvature of the first annular or connecting zone is greater than that of the central zone. In addition, such a design provides a vast amount of alternative methods of manufacture, and lifts the constraint of requiring the origin of the radius of curvature for the first annular zone curve to reside on the central axis of the central base curve or zone.

Ophthalmic conditions such as presbyopia, myopia, and astigmatism can be corrected by the use of a molding contact lens in combination with a pharmaceutical composition suitable for delivery to the eye. The molding contact lenses are preferably commercially available and are not specifically designed for orthokeratology. The agents in the pharmaceutical compositions such as hyaluronase allow the cornea of the eye to be molded in order to correct the refractive error of the eye. The contact lenses and the pharmaceutical composition induce a change in the radius of curvature of the anterior surface of the cornea, thereby correcting the refractive error of the eye. One advantage of the inventive technique is that the patient with his or her own individual visual needs guides the treatment until the patient near and far visual needs are met. The present invention also provides for kits, which contain molding contact lenses, pharmaceutical composition suitable for delivery to the eye, and instructions, useful in the inventive system.

The invention relates to a method for manufacturing an orthokeratology lens. The orthokeratology lens comprises an inner surface facing cornea of the human beings when in wearing and an outer surfaceopposite to the inner surface, wherein the inner surface comprises a basic arc area disposed at the center. The method comprises the following steps: determining a maximum curvature radius of the basic arc area; determining a presbyopia correction amount for a wearer; determining a minimum curvature radius of the basic arc area; and manufacturing the orthokeratology lens, so that the basic arc area comprises two or more regions, a first region in the two or more regions has the maximum curvature radius, and the second region of the two or more regions has the minimum curvature radius. The orthokeratology lens manufactured according to the method of the invention can play a role in correcting ametropia and presbyopia.

The invention relates to an orthokeratology lens. The internal surface of the orthokeratology lens is continuously provided with a basic curve zone, a reverse curve zone, a positioning curve zone and a circumference curve zone from center to outside. The center of a circle of the basic spherical curve of the reverse curve zone is not in a line connecting the center of a circle of the basic spherical curve of the basic curve segment and the center of a circle of the basic spherical curve of the positioning curve segment. The orthokeratology lens can control a refractive power difference between the reverse curve and the basic curve in a stable value, so the stable volume of a tear storage space is guaranteed, and the wearing safety and validity of the lens is guaranteed; the matching degree of a lens matching curve zone and the shape of cornea is improved, the quantity of curve zone connecting segments is reduced, and the surface cleanness is improved; and the wearing visual sense quality of a patient is improved.

The invention is applied to the field of orthokeratology glasses,and provides orthokeratology glasses with an ultra-high or ultra-low cornea K value and a designing method thereof. According to the orthokeratology glasses,the positioning problems of the orthokeratology glasses in special cornea forms is solved by conducting optometry computing with accurate cornea topographic map data adding withophthalmology experience data,and suitable orthokeratology glasses can be designed for corneas with the cornea flat K values between 46.5 D-53 D and between 39.0 D-33.5 D to greatly expand the using range of the orthokeratology glasses.

The invention relates to an orthokeratology lens for myopia correction and control, wherein the inner surface is divided into four regions such as a base arc region, a reverse arc region, a modulation arc region and a periphery arc region from the center to the edge, the modulation arc region is a spherical or aspherical arc connected with the reverse arc region and the periphery arc region, and various small width waveform modulations are performed so as to effectively increase a center positioning function of the orthokeratology lens, promote lacrimal fluid exchange, optimize positive pressure of the base arc region, and increase the effective pressure surface of the base arc region.

The embodiment of the invention provides a method and a device for checking and fitting an orthokeratology lens. The method comprises the following steps: obtaining corneal topography data, wherein the corneal topography data comprise corneal eccentricity ratio and flat meridian refractive power; computing the diopter of a location arc of a cornea according to the corneal topography data and a preset correction value; computing the target diopter of a try-on orthokeratology lens according to the computed diopter of the location arc of the cornea and the corneal eccentricity ratio; outputting the target diopter, and reminding to select and try on a corresponding orthokeratology lens according to the target diopter. In such a way, the diopter suitable for the try-on orthokeratology lens canbe computed according to the corneal topography data, so that the checking and fitting accuracy of theorthokeratology lens is increased, and theoretical support is provided for checking and fitting oftheorthokeratology lens.

A corneal reshaping by means of a soft contact lens to manipulate tear pressure gradient to produce a dimensional change to the surface profile of the cornea of the wearer to provide at least a temporary change in the refractive state of the eye eliminating the need for other refractive corrections. The contact lens has mechanical properties and / or a geometric shape such that when the lens is fitted to the eye the pressure applied to the eye via the lens will vary in a radial direction between at least one zone of higher pressure and at least one zone of lower pressure so that wearing the lens will over time cause a dimensional change to the surface layer of the cornea.

The invention belongs to the technical field of orthokeratology lenses, and particularly relates to an intelligent orthokeratology lens selection system and method based on big data and deep learning.The invention provides a novel intelligent orthokeratology lens selection system and method based on big data and deep learning. According to the intelligent orthokeratology lens selection system andmethod based on big data and deep learning, machine learning is carried out through lens model data and corresponding historical corneal data, and a model identification data model is constructed; the lens model of the shaping lens is identified through the model identification data model based on the actual cornea data, the determined lens model data is output after verification is completely passed, and identification verification is performed in a gradient and weighting mode after verification is partially passed, so that the purpose of rapidly, accurately and stably identifying the lens model data is achieved.

The invention discloses an orthokeratology lens cleaning instrument, which comprises a base, a plastic cover fixed on the base, a lithium battery fixed on the upper end of the plastic cover, an operation interface fixed on the plastic cover, Two micro-vacuum pumps on the base, cleaning fluid on the plastic cover, magnetic module on the plastic cover, two stepping motors on the magnetic module, two stepping motors respectively The two orthokeratology lens clips on the top, the two cleaning nozzles on the side wall of the plastic case, the sewage tank that is movable on the base, the sewage baffle fixed on the sewage tank, and the sewage baffle on the base. Fixtures for securing it.

The invention discloses lenses, glasses and methods for obtaining defocusing amount parameters, ophthalmic dispensing and evaluating an effect. The peripheral defocusing lens comprises a central optical zone, the central optical zone is externally provided with an annular defocusing zone, and the defocusing amount of the defocusing zone varies in the circumferential direction. At least one of a base curve zone and a reverse curve zone of the orthokeratology lens has a structural change in the circumferential direction. The method for obtaining the defocusing amount parameters comprises the steps that the defocusing amount of a plurality of sample points on a dioptric system composed of a myopic patient cornea and the lens or on a user cornea is collected, and the sample points are distributed on a plurality of direction angles in a coordinate system with the cornea center as the origin; and the defocusing amount parameters are obtained according to the defocusing amount of the multiplesample points on the cornea. The method for determining the myopia control effect of the orthokeratology on a myopia patient according to the defocusing amount parameters is further provided.

A corneal reshaping by means of a soft contact lens to manipulate tear pressure gradient to produce a dimensional change to the surface profile of the cornea of the wearer to provide at least a temporary change in the refractive state of the eye eliminating the need for other refractive corrections. The contact lens has mechanical properties and / or a geometric shape such that when the lens is fitted to the eye the pressure applied to the eye via the lens will vary in a radial direction between at least one zone of higher pressure and at least one zone of lower pressure so that wearing the lens will over time cause a dimensional change to the surface layer of the cornea.

Two types of compositions having an eye-drop delivery system are used during or after an orthokeratology procedure to prevent or retard relaxation of corneal tissue back to the original anterior curvature of the cornea. Each composition functions independently from the others and is a different approach of preparing a stabilizing agent. The first composition is directed to a biologically compatible composition comprising fibril associated collagens with interrupted triple helices (FACITs) and / or small leucine-rich repeat proteoglycans (SLRPs). The fibril associated collagen family includes various types of collagens, such as type VI, type XX, type XII, and type XIV. The small leucine-rich repeat proteoglycans family includes decorin, keratocan, biglycan, epiphycan, lumican, mimecan, and fibromodulin. The second composition includes the enzyme found as a normal component of tissues, plasma, or epidermis, such as transglutaminase.

The invention discloses a design method for an orthokeratology lens. In the technical scheme provided by the invention, coordinates of all arc sections of the inner surface of the orthokeratology lensare obtained by establishing a corneal model formula; all the arc sections of the inner surface of the orthokeratology lens are determined by combining the relationship between cross-sectional areasand integral areas of tear films in all arc section areas and points on corresponding arc sections, so that more accurate actual shape of analogous parabola of cornea is combined in the design of theorthokeratology lens; meanwhile, by considering the setting of higher model resolution, the design has the capability of correcting refractive errors more accurately; by using the design of the tear films and controlling the cross-sectional areas and the integral areas of the tear films in all the arc section areas, storage capacity of tears is more stable, and further the stability of a shaping effect of the orthokeratology lens is ensured; meanwhile, central locating property of the orthokeratology lens can also be improved.

The invention provides a method for determining an AC value of an orthokeratology lens. The method comprises the following steps of: S1, acquiring parameters of a cornea of a patient, wherein the parameters comprise a cornea flatness K value, a cornea e value and a cornea diameter; S2, calculating a cornea rise according to the parameters acquired in the step S1; S3, matching a lens rise closest to the cornea rise in a lens database; and S4, taking the AC value of the orthokeratology lens corresponding to the lens rise as the AC value of the orthokeratology lens needing to be produced. The invention further provides a system for determining the AC value of the orthokeratology lens, which is used for realizing the method. According to the method and the system, the influence of different experiences of different optometrists on the accuracy of measurement of the AC value of the orthokeratology lens is avoided, the difficulty of lens matching is reduced, and the standardization degree of lens matching is improved.

The invention discloses an angle-adjustable orthokeratology lens polishing device. The angle-adjustable orthokeratology lens polishing device comprises a shell, a rotating mechanism, an adjusting mechanism and a polishing mechanism, wherein the rotating mechanism comprises a sealing plate, a bearing seat, a first motor and a fixing plate, the sealing plate is fixedly connected with the top surface of a base, the bearing seat is fixedly connected to the surface of the base located in the sealing plate, the top of the bearing seat is fixedly connected with the first motor, the output end of the first motor is fixedly connected with a first output gear, the first output gear is connected with a first transmission gear in a meshed mode, the first transmission gear is fixedly connected with a rotating shaft, and a fixing plate is fixedly connected to the top of the rotating shaft; the adjusting mechanism comprises a fixing block, a movable ball and a supporting plate, the fixing block is fixedly connected with the middle of the top surface of the fixing plate, and the interior of the fixing block is movably connected with the movable ball in a chimeric mode. The angle-adjustable orthokeratology lens polishing device has the beneficial effects that the angle-adjustable orthokeratology lens polishing device is reasonable and reliable in structure, and a polishing angle can be conveniently adjusted.