The invention relates to a brain protein hydrolyzate compound preparation for nerve protection and nerve repair and a preparation method thereof, belonging to the technical field of pharmacy. In order to solve the problem that the existing cerebroprotein hydrolyzate easily causes allergies and the oral utilization rate is low, the present invention provides a compound preparation of cerebroprotein hydrolyzate for neuroprotection and nerve repair, and the compound preparation is nasal mucosa administration preparation , containing 0.1-5wt% of cerebroprotein hydrolyzate, and also containing pharmaceutical auxiliary materials and water for injection. Administered through the nasal cavity, absorbed through the nasal mucosa, it can be absorbed into the brain in the respiratory area and olfactory area of the nasal cavity, and directly enter the central nervous system. It has the characteristics of rapid absorption, high bioavailability, small side effects, and convenient administration. In the present invention, the brain protein hydrolyzate is made into nano-scale liposomes, so that the active ingredients are more easily absorbed through the mucous membranes, efficiently enter the brain cells and play a role, can maintain the local drug concentration stably for a long time, reduce the drug dosage, and are not easy to cause adverse effects on the body. reaction.