93 results about "Peripheral veins" patented technology

A dual mode handheld ultrasonic device is provided for guiding a venous access catheter into a patient's peripheral vein. It provides B-mode imaging with a predetermined aperture and operating frequency which locates and displays a gray scale cross-sectional image of the target blood vessel. A single doppler beam in a separate mode detects the same blood vessel and creates a single scanline image superimposed to such B-mode cross-sectional image. Simultaneously, the intensity of the positive doppler shift detected by the single doppler beam as it hits the target blood vessel activates a plurality of light emitting diode (LED) indicator lights with varying voltage requirements mounted in the scanhead. Activated LED indicator lights forms an arrow pointing inferiorly perpendicular to the target vessel which guides a physician or a paramedical professional to the precise catheter insertion spot on a patient's extremity while simultaneously viewing the target blood vessel's cross-section on the display screen.

A new PPG / SpO2 based ear hook sensor was constructed with the PPG / SpO2 sensors are attached to the skin in the regions of superficial artery and vein (010) and posterior auricular artery and vein around the ear (011 of FIG. 1C). An ear wearable heart rate monitor is constructed with PPG / SpO2 sensors are attached to the skin in the regions of superficial artery and vein (010) and posterior auricular artery and vein around the ear (011 of FIG. 1C) (temporal region of the head). This sensor system is less vulnerable to motion artifacts hence capable of producing high quality PPG signals under motion conditions such as running and exercising.

Method and apparatus for the extracorporeal treatment of blood by utilizing a peripherally inserted dual lumen catheter assembly for the continuous removal and return of blood for renal replacement treatment, in particularly, treatment of congestive heart failure and fluid overload by ultrafiltration. A catheter is inserted in a peripheral vein and maneuvered upward through the vascular system to access the reservoir of blood in the large or great veins for continuous blood withdrawal and treatment. Air-tight connectors are incorporated in the catheter assembly to overcome the untoward effects of negative pressure in blood withdrawal.

A system and method for increasing the speed of blood and wall shear stress (WSS) in a peripheral vein for a sufficient period of time to result in a persistent increase in the overall diameter and lumen diameter of the vein is provided. The method includes pumping blood at a desired rate and pulsatility. The pumping is monitored and adjusted, as necessary, to maintain the desired blood speed, WSS and pulsatility in the peripheral vein in order to optimize the rate and extent of dilation of the peripheral vein.

An endovenous laser fiber optic member for endovenous laser therapy of peripheral veins of the body including a heat resistant insulative tip shield covering the distal end of the laser fiber optic. The tip shield may have echogenic qualities to increase ultrasound reflectivity. The tip shield also improves deflectability of the distal end and acts as a thermal break.

A blood pump system for persistently increasing the overall diameter and lumen diameter of peripheral veins and arteries by persistently increasing the speed of blood and the wall shear stress in a peripheral vein or artery for a period of time sufficient to result in a persistent increase in the overall diameter and lumen diameter of the vessel is provided. The blood pump system includes a blood pump, blood conduit(s), a control system with optional sensors, and a power source. The pump system is configured to connect to the vascular system in a patient and pump blood at a desired rate and pulsatility. The pumping of blood is monitored and adjusted, as necessary, to maintain the desired elevated blood speed, wall shear stress, and desired pulsatility in the target vessel to optimize the rate and extent of persistent increase in the overall diameter and lumen diameter of the target vessel.

A dual-mode, capable of imaging and ablation, ultrasound array integrated in a catheter is provided for minimally invasive treatment of arrhythmias. The catheter array is small enough for insertion through a peripheral vein and is longitudinally integrated with the catheter to have a side-view for tissue imaging and ablation. A high length / width array ratio creates a large aperture necessary for high power ablation densities. A catheter stabilization device maintains a distance between the catheter array and the wall of a heart or vein. Visualization of anatomy and imaging of ablated tissue provides a guide for placing the lesion and assists in achieving a pattern of ablated tissue. The catheter is advanced to another area by catheter rotation and / or array steering or focusing. Gating the imaging and ablation processes to a heart cycle allows for accounting and compensation of heart motion and enables automation of an arrhythmia treatment.

Method and apparatus for the extracorporeal treatment of blood by utilizing a peripherally inserted dual lumen catheter assembly for the continuous removal and return of blood for renal replacement treatment, in particularly, treatment of congestive heart failure and fluid overload by ultrafiltration. A catheter is inserted in a peripheral vein and maneuvered upward through the vascular system to access the reservoir of blood in the large or great veins for continuous blood withdrawal and treatment. Air-tight connectors are incorporated in the catheter assembly to overcome the untoward effects of negative pressure in blood withdrawal.

A method and apparatus for ultrafiltration of blood operating by removing blood from a peripheral blood vessel at a rate of less than two percent of total cardiac output of a patient, extracting fluid at a rate of 0.1 liter to 1.0 liters per hour while retaining cells and proteins in the blood, and returning the concentrated blood to a secondary blood vessel is disclosed. Blood is removed and returned using small gage needles. As a pump circulates blood from the patient, a filter removes ultrafiltrate from the blood using duty cycle or pump control, and a transparent container collects the removed fluid.

A peripherally inserted catheter assembly having multiple side holes to be inserted in a peripheral vein and maneuvered upward through the vascular system to access the reservoir of blood beyond and between the venous flappers for continuous blood withdrawal and treatment.

An extracorporeal blood circuit is disclosed for withdrawing, filtering and returning blood from peripheral blood vessels. The blood passage in the circuit extends through a withdrawal tube connected to a catheter in a peripheral vein, a filter, one or more pressure sensors and return tube also connected to a catheter in a peripheral vein (which may or may not be the same vein as used for the withdrawal tube). The blood passage is air free, and has smooth passage walls which promoted continuous and uniform flow of the blood through the circuit.

A venovenous expandable dialysis apparatus includes a blood feeding needle component configured to introduce blood at a position of a first peripheral vein and a blood withdrawal needle component configured to withdraw blood at another position from a second peripheral vein located, where the first position is located away from the second position. The expandable dialysis apparatus further includes a guide wire having a central axis, an expanding sheath configured circumferentially around the guide wire to form an annular lumen between a distal blood withdrawal position and a proximal extracorporeal position; and a needle disposed around the expandable sheath.

An endovenous laser fiber optic member for endovenous laser therapy of peripheral veins of the body including a flexible heat resistant tip shield covering the distal end of the laser fiber optic. The tip shield has an irregular surface to increase ultrasound reflectivity. The tip shield also improves deflectability of the distal end and acts as a heat sink and heat energy dissipater.

A method and apparatus for inserting and monitoring the placement of a cannula tip within a peripheral vein of a human body where the cannula includes a sensor located at predetermined location and mounted on the cannula for sensing the biological material of the body to guide the insertion of the cannula tip into the vein and alerts to the withdrawal of the cannula tip from the vein in the body.

A method and apparatus for inserting and monitoring the placement of a cannula tip within a peripheral vein of a human body where the cannula includes a sensor located at predetermined location and mounted on the cannula for sensing the biological material of the body to guide the insertion of the cannula tip into the vein and alerts to the withdrawal of the cannula tip from the vein in the body.

A system and method for increasing the speed of blood and the wall shear stress in a peripheral artery or peripheral vein to a sufficient level and for a sufficient period of time to result in a persistent increase in the overall diameter and lumen diameter of the artery or vein is provided. The method includes systems and methods to effect the movement of blood at the desired rate and in the desired direction. The movement of blood is monitored and adjusted, as necessary, to maintain the desired blood speed and wall shear stress in the peripheral artery or vein in order to optimize the rate and extent of persistent diameter increase of the peripheral artery or peripheral vein.

The present disclosure relates to a rotary blood pump with a double pivot contact bearing system with an operating range between about 50 mL / min and about 1500 mL / min, wherein the force on the upper bearing is less than 3N during operating speeds up to 6000 rpm. The disclosure also relates to a method of using a blood pump system for persistently increasing the overall diameter and lumen diameter of peripheral veins and arteries by persistently increasing the speed of blood and the wall shear stress in a peripheral vein or artery for period of time sufficient to result in a persistent increase in the overall diameter and lumen diameter of the vessel.

The invention belongs to the medical teaching equipment technical field and relates to a fully-automatic multi-functional integrated puncture training computer dummy. The fully-automatic multi-functional integrated puncture training computer dummy comprises a high-simulation human body model, a position-automatic changing experimental table, puncture cavities, modules, arteriovenous veins, a liquid injection automatic control device, a fully-automatic arterial pulse simulator and a microcomputer controller. The dummy is characterized in that the high-simulation human body model is installed on the position-automatic changing position experimental table and is provided with various puncture cavities / modules such as pneumothorax, hydrothorax and abdominocentesis modules which are all connected with the microcomputer controller and / or a micro water pump / air pump; double-layer metal mesh electrodes are distributed on the neck, thoracic puncture and lumbar puncture positions of the dummy; the dummy is further provided with kidney, bladder, lymph gland and bone marrow puncture cavities / modules as well as a variety of puncturable central veins and peripheral veins; and arteries are connected with a fully-automatic blood circulation simulator. With the dummy adopted, dozens of puncture items can be provided; puncture position change, liquid injection, gas injection and artery pulsing are completely automated; and sound-light alarms can be given out automatically; life-like simulation effects can be realized; and teaching effects can be significantly improved.

The invention discloses a stem cell preparation for treating cirrhosis, which is prepared from stem cells from human umbilical cord placenta, normal saline containing seralbumin with concentration by volume being 0.5-5%, and low-molecular-weight heparin sodium with concentration being 50-701U / ml. When the stem cell preparation is transfused into a rat model with cirrhosis through a caudal vein, the effective dose of the stem cell preparation is 5*106 cells each time; and the effective dose of the stem cell preparation is 0.5-5*106 cells / kg each time when the stem cell preparation is transfused into a patient with cirrhosis through a peripheral vein. After applied to rats with cirrhosis and patients with cirrhosis, the stem cell preparation can obviously improve the survival rate of the rats with cirrhosis and the patients with cirrhosis, retard and invert a cirrhosis process, improve a whole state and a liver function state, and promote pathological recovery of liver, thereby developing a new way to cell therapy for treating cirrhosis.

A method and apparatus for inserting and monitoring the placement of a cannula tip within a peripheral vein of a human body where the cannula includes a sensor located at predetermined location and mounted on the cannula for sensing the biological material of the body to guide the insertion of the cannula tip into the vein and alerts to the withdrawal of the cannula tip from the vein in the body.

A catheter delivers an electrode within a vein for a minimally invasive treatment of varicose veins and venous insufficiency using RF energy. The catheter is introduced into a patient and positioned within the section of the vein to be treated. The electrode radiates high frequency energy towards the vein, and the surrounding venous tissue becomes heated and begins to shrink. The catheter includes a controllable member for limiting the amount of shrinkage of the vein to the diameter of the member. The electrode remains active until there has been sufficient shrinkage of the vein. The extent of shrinkage of the vein may be detected by fluoroscopy. After treating one section of the vein, the catheter and the electrode can be repositioned intraluminally within the vein to treat different sections of the vein until all desired venous sections and valves are repaired and rendered functionally competent.

The present invention has multiple aspects. In particular, in one aspect, the present invention is directed to a unit dose composition comprising 0.2 μg / kg to 48 μg / kg of an FGF-2 of SEQ ID NO: 2, or an angiogenically active fragment or mutein thereof in a pharmaceutically acceptable carrier. In another aspect, the present invention is directed to a method for treating a human patient for coronary artery disease, comprising administering into one or more coronary vessels or a peripheral vein of a human patient in need of treatment for coronary artery disease a safe and angiogenically effective dose of a recombinant FGF-2, or an angiogenically active fragment or mutein thereof. The single unit dose composition of the present invention provides an angiogenic effect in a human CAD patient that lasts 2 months before re-treatment is required. In another aspect, the present invention is directed to a method of administration which optimizes patient's safety. In this embodiment, fluids, heparin and / or rate of infusion all play a role. In another aspect, the present invention is directed to a pharmaceutical composition comprising a therapeutically effective amount of FGF-2, alone or in combination with heparin, in a therapeutically effective carrier. The magnitude and duration of benefit were unexpected; in addition benefit with the IV route was unexpected.

Systems and methods for optimizing CRT are disclosed. According to an aspect, a method includes receiving, during at least two time periods of a cardiac cycle, electrical signals communicated by two or more electrodes of a CRT device positioned one or more of on a surface of a body, within a thorax of the body, a heart of the body, a surrounding venous structure of the body, and a surrounding subcutaneous structure of the body. The method also includes calculating, based on the received electrical signals, spacing between the two or more electrodes during the at least two time periods of the cardiac cycle. Further, the method includes controlling output of the CRT device to the electrodes based on the calculated spacing between the two or more electrodes.

The invention provides an in-vivo enrichment device for circulating tumor cells. The in-vivo enrichment device comprises a catheter body capable of puncturing to a central vein through a peripheral vein, a plurality of sieve holes are formed in the catheter wall of the catheter body, the catheter body is filled with trapped particles of targeting circulating tumor cells, and a blind end is arranged at the front end of the catheter body. According to the in-vivo enrichment device for the circulating tumor cells, the inside of the catheter body is filled with assembling hydrophilic medicine or trapped particles of a specific antibody, the sieve holes are formed in the pipe wall of the catheter body, CTC in blood is continuously combined on the trapped particles inside the catheter body through specific targeting accordingly, and efficient and high-quality trapping of the CTC in blood is achieved; the in-vivo enrichment device has the advantages that the enrichment device is used in vivo, efficient trapping is achieved, and clinical application is convenient; the in-vivo enrichment device can provide molecular-gene diagnosis information based on the CTC for early diagnosis, targeting therapy, recurrence and metastasis detection, treatment evaluation and the like of tumor, and has quite-broad application prospects.

In emergency, the optimal method for building an emergency transfusion channel is intra-bone marrow transfusion which ensures that a medicament and liquid transfused into the marrow cavity can quickly and effectively enter blood circulation. The time for the medicament administrated from intra-bone marrow to enter systemic circulation is basically the same as that for the medicament which is administrated from central veins to enter the systemic circulation, but is quicker than that for the medicament which is administrated from peripheral veins to enter the systemic circulation. For criticalpatients who cannot be treated by regular vein puncture, the intra-bone marrow transfusion may be a first choice instead of the traditional venous transfusion is quick, safe and effective rescue technology and saves precious time for life rescue. In the invention, a medullo-puncture needle is penetrated into the marrow cavity by a mechanical energy releasing device to feed the medicament and the liquid into the veins. The disposable intra-bone marrow injection device drives the medullo-puncture needle into the intra-bone marrow by the mechanical energy released by winded clockwork springs.

The invention discloses a supporting type automatic squatting pan. The supporting type automatic squatting pan is composed of a squatting pan and box body structure, a squatting pan bracket, a plurality of U-shaped connection blocks, a first supporting sliding mechanism, a second supporting sliding mechanism, a base and a controller, wherein the first supporting sliding mechanism and the second supporting sliding mechanism are fixedly arranged on the base respectively; the squatting pan bracket is fixedly arranged at the lower end of the squatting pan and box body structure; the plurality of U-shaped connection blocks are fixedly arranged at the lower end of the squatting pan bracket; the upper ends of the first supporting sliding mechanism and the second supporting sliding mechanism are hinged onto the plurality of U-shaped connection blocks respectively; the controller is arranged on the squatting pan and box body structure. The mechanism has a few of joints and kinematic pairs are low pairs; the mechanism has relatively small self inertia, is convenient to manufacture and mount and is relatively low in cost; a user defecates by adopting a squatting posture so that body and mental health of the user is facilitated and the user can completely urinate to the greatest extent; a condition that anus peripheral vein reflux is blocked due to self weight of a human body can be reduced and risks of hemorrhoids are reduced.

The present invention has multiple aspects. In particular, in one aspect, the present invention is directed to a unit dose composition comprising 0.2 μg / kg to 48 μg / kg of an FGF-2 of SEQ ID NO: 2, or an angiogenically active fragment or mutein thereof in a pharmaceutically acceptable carrier. In another aspect, the present invention is directed to a method for treating a human patient for coronary artery disease, comprising administering into one or more coronary vessels or a peripheral vein of a human patient in need of treatment for coronary artery disease a safe and angiogenically effective dose of a recombinant FGF-2, or an angiogenically active fragment or mutein thereof. The single unit dose composition of the present invention provides an angiogenic effect in a human CAD patient that lasts 2 months before re-treatment is required. In another aspect, the present invention is directed to a method of administration which optimizes patient's safety. In this embodiment, fluids, heparin and / or rate of infusion all play a role. In another aspect, the present invention is directed to a pharmaceutical composition comprising a therapeutically effective amount of FGF-2, alone or in combination with heparin, in a therapeutically effective carrier. The magnitude and duration of benefit were unexpected; in addition benefit with the IV route was unexpected.