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173 results about "NERVOUS DISORDERS" patented technology

Parkinson’s disease is a nervous system disorder whose main symptoms include tremors, rigidity of the trunk and extremities, slow movement and balance disorders. This nervous system disorder arises from a loss of brain cells that produce dopamine.

Compositions, methods, and systems for rapid induction and maintenance of continuous rem sleep

InactiveUS20090198145A1Rapid eye movementPromote recoveryBiocideNervous disorderDiseaseSleep state
Compositions, kits, methods, and systems to induce, maintain, monitor, and interpret a continuous, un-fragmented REM sleep state in humans, generate dreams, recover sleep, create brain neuronal plasticity and activate the brain for cognition enhancement and mood stabilization are described. If potentially combined with other medications, a platform is provided to develop new research and therapies in many fields treating the human brain. The procedure reliably and quickly generates a Continuous REM Sleep cycle of pre-determined time or indefinite duration depending on therapeutic goals, allowing the patient to experience a qualitatively superior dream sleep in a shortened period of time compared to a natural sleep cycle. Profuse positive (pleasant) dreams are produced as well. REM sleep, dreams and sleep recovery can be reliably generated, and various sleep, psychological and neurological illnesses and disorders can be treated or prevented either solely by this method or in combination with additional agents.
Owner:CHOW HARRISON

Methods and systems for treatment of neurological diseases of the central nervous system

The present invention is directed to methods and systems for the treatment of inborn genetic errors or other defects that cause deficiencies of active enzymes or proteins within the cells of the central nervous system. Such methods and systems generally comprise an implantable catheter system designed for the chronic delivery of specially formulated proteins to intrathecal, intracerebroventricular, and / or intraparenchymal regions of the central nervous system. The invention has application in the neuropathic aspects of the broad category of lysosomal storage diseases. These genetic based diseases are the result of insufficient enzyme activity to catabolize specific substances, which thereby accumulate in the cellular lysosomes.
Owner:MEDTRONIC INC

Methods and apparatus for relieving headaches, rhinitis and other common ailments

Apparatus, methods, and kits for treating symptoms associated with common ailments, such as headaches, rhinitis, asthma, epilepsy, nervous disorders and the like, are provided. The apparatus comprises dispensers for carbon dioxide and other therapeutic gases. The methods comprise delivering small volumes of these gases to patients in a manner where the gas infuses into a body region in order to bathe the mucous membranes therein. It has been found that even very short exposure of patients to small volumes and high concentrations of such gases can provide significant relief from symptoms.
Owner:CAPNIA INC

Noveltreatment for neurological disorders

Provided are novel drugs and methods in the treatment as well as diagnosis of neurological disorders such as Alzheimer's disease and amyloid-beta pathology / amyloidosis. More specifically, the use of erythropoietin and analogs thereof for the treatment of Aβ peptide related brain impairments is described. Furthermore, the use of claudin-5 and variants thereof as biomarker for Alzheimer's disease and for the progression of Alzheimer's disease, respectively, is provided.
Owner:UNIV ZURICH

Animal model simulating neurologic disease

The present invention relates to the development of a pharmacological non-human animal model that associates memory loss to histopathological features found in the brain of a subject having Alzheimer's Disease. In one embodiment, a four-week continuous infusion of a Fe2+, Aβ42 and buthionine sulfoximine (FAB) solution in the left ventricle of young adult Long-Evans rats induced memory impairment accompanied by increased hyperphosphorylated Tau protein levels in cerebrospinal fluid. Brains from treated animals displayed neuritic plaques, tangles, neuronal loss, astrogliosis and microgliosis in hippocampus and cortex. The present invention may be utilized in evaluating preventive, therapeutic and diagnostic means for neurologic diseases.
Owner:SAMARITAN PHARMA +1

Compositions and Methods for Identifying Autism Spectrum Disorders

InactiveUS20130012403A1Nucleotide librariesMicrobiological testing/measurementMicrorna profilingMicroRNA Profile
The compositions and methods described are directed to microRNA chips having a plurality of different oligonucleotides with specificity for genes associated with autism spectrum disorders. The invention further provides methods of identifying microRNA profiles for neurological and psychiatric conditions including autism spectrum disorders, methods of treating such conditions, and methods of identifying therapeutics for the treatment of such neurological and psychiatric conditions.
Owner:GEORGE WASHINGTON UNIVERSITY

Xenotransplant for CNS therapy

Disclosed are implant compositions and methods for treatment of neurological diseases of the central nervous system of a mammal.
Owner:NEUROTROPHINCELL

Slow intraventricular delivery

Neurological diseases, including lysosomal storage diseases, can be successfully treated using intraventricular delivery of the therapeutic agents to bypass the blood-brain barrier. Similarly, diagnostic agents and anesthetic agents can be delivered to the brain in this manner. The administration can be performed slowly to achieve maximum effect. Such administration permits greater penetration of distal portions of the brain.
Owner:GENZYME CORP

2-Oxo-piperidinyl- and 2-oxo-azepanyl alkanoic acid derivatives for the treatment of epilepsy and other neurological disorders

This invention relates to new 2-oxo-piperidinyl- and 2-oxo-azepanyl alkanoic acid derivatives of formula (1) having anticonvulsant activity which are useful as therapeutic agents for the treatment or prevention of epilepsy and other neurological disorders. The invention also concerns processes for preparing these derivatives and novel intermediates used in the preparation of these derivatives.
Owner:UCB SA

Uses of chemicals to modulate GSK-3 signaling for treatment of bipolar disorder and other brain disorders

Aspects of this invention are related, at least in part, to the use of chemical compounds able to inhibit GSK-3 and / or to stabilize β-catenin and formulations thereof. Some aspects of this invention relate to compositions comprising such compounds. Some aspects of the invention provide methods of using such compounds and / or compositions in the treatment of subjects having a neurological disease and / or psychiatric disorder. Some aspects of this invention provide methods of using ruboxistaurin, enzastaurin, sunitinib, midostaurin, lestaurtinib, 7-hydroxystaurosporine, and / or Chir99021 in the treatment of subjects having a neurological disease and / or psychiatric disorder. In some embodiments, compounds are administered in combination with Lithium.
Owner:MASSACHUSETTS INST OF TECH +1

Aralkyl piperidine (piperazidine) derivate and use thereof in mental disease treatment

The invention discloses an aralkyl piperidine (oxazine) derivative and an application of the derivative in treating neurological and mental diseases. Pharmacological tests show that the derivative has a good effect of resisting schizophrenia and little toxicity. The derivative is free alkali or salt of a compound having the following structure general formula.
Owner:JIANGSU HENGYI PHARMA +1

Supplements for pain management

Dietary supplements, compositions and methods of administering the supplements to reduce pain, inflammation and stiffness in said mammal within a few hours. The supplements and compositions can include a combination of an amino acid, vitamins, herbs and enzymes. The composition / supplement can be put in capsule form and when administered to mammals can reduce these symptoms within approximately two hours. reducing the pain and inflammation associated with chronic joint discomfort, chronic low back pain, muscle strain, arthritis, sports injuries, normal everyday bumps and bruises. The novel composition has also been shown to be very effective in reducing monthly menstrual symptoms (PMS). The novel composition can also have benefits for other ailments such as but not limited to Osteoarthritis, Cardiovascular disease, Neurological ailments, Alzheimer disease, and Cancer.
Owner:RELEANA LLC

Point-of-care tele monitoring device for neurological disorders and neurovascular diseases and system and method thereof

Disclosed herein an improved systems and methods using point-of-care (POC), IoT (Internet of Things) enabled device(s) which captures different bio-signals simultaneously as distinct signals, by targeting same neurovascular substrate. The synchronized streaming of the data for live analysis or recording in the tele neuro-monitoring platform are jointly processed in an Artificial Intelligence (AI) based big-data platform under a closed loop, bi-directional, decision tree based system for brain / neurological function status monitoring (continuously and / or intermittently) leading to online POC diagnosis, severity classification, and prognosis of neurological disorders and neurovascular diseases.
Owner:SENGUPTA RAJIB +2

Combination product for the treatment of neurological and/or psychiatric disorders

ActiveUS20200397752A1Promoting neurogenesisOrganic active ingredientsNervous disorderDiseaseNeurogenesis
The present application provides a combination product for the treatment and / or prevention of psychiatric and / or neurological disorders. The combination product comprises (i) a compound which promotes neurogenesis and has hallucinogenic and / or psychedelic side effects, and (ii) a 5-HT2A receptor antagonist which alleviates and / or removes the hallucinogenic and / or psychedelic side effects caused by the first compound.
Owner:TERRAN BIOSCIENCES INC

Neural specific s100b for biomarker assays and devices for detection of a neurological condition

An in vitro diagnostic (IVD) device is used to detect the presence of and / or severity of neural injuries or neuronal disorders in a subject. The IVD device relies on an immunoassay which identifies biomarkers that are diagnostic of neural injury and / or neuronal disorders in a biological sample, such as whole blood, plasma, serum, and / or cerebrospinal fluid (CSF). An IVD device may measure one or more of several neural specific markers in a biological sample and output the results to a machine readable format, either to a display device or to a storage device internal or external to the IVD.
Owner:BANYAN BIOMARKERS INC

Agilawood compound essential oil capable of improving sleeping

The invention belongs to the technical field of health products, and in particular relates to agilawood compound essential oil capable of improving sleeping, prepared by uniformly mixing agilawood essential oil, lavender essential oil, camomile essential oil and grape seed oil. Because natural plant extracts are scientifically matched, the agilawood compound essential oil can effectively improve the sleeping quality and prolong the sleeping time, and is mainly used for nervous disorder insomnia caused by factors such as increased working pressure, accelerated life rhythm, high frequency of night life and the like.
Owner:INST OF MEDICINAL PLANT DEV CHINESE ACADEMY OF MEDICAL SCI HAINAN BRANCH +1

Method of Treating Neurological Conditions with Oleandrin

A method of treating neurological condition in a subject by administration of a cardiac glycoside is provided. Alzheimer's disease, Huntington's disease or stroke are treated by administering a therapeutically effective amount of cardiac glycoside, and optionally triterpene(s), to a subject. The cardiac glycoside can be present in a dosage form.
Owner:PHOENIX BIOTECH INC

Therapeutic agent for psychoneurotic disease

The present invention relates to a preventive and / or therapeutic agent for psychoneurotic diseases, comprising an EP3 antagonist represented by the general formula (I):(wherein the meanings of characters are defined in the description). This compound has an antagonistic potency against EP3 and exhibits efficacy through unusual action mechanism as a preventive and / or therapeutic agent for psychoneurotic disorder, psychosomatic disorder, anxiety disorder, depression and disorder caused by stress.
Owner:ONO PHARMA CO LTD

Patient Management Device, System And Method

A portable apparatus for managing a plurality of events related to a patient and for recording and storing input data related to said events is disclosed. The portable apparatus comprises a man machine user interface; a timer unit; a control unit, arranged to provide an invitation to the patient as an instruction via the interface to perform a motion exercise, upon a trigger from the timer unit or upon a patient self initiation. In an embodiment the apparatus comprises a sensor to record measurements related to said motion exercise. Further, a storage unit is arranged to retrievably store patient input data and said measurements. This enables diagnosing a degree of a neurological disease or an effect of a medication on said neurological disease.
Owner:KIPAX
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