The invention discloses
bifidobacterium longum subsp.infantis for relieving
colitis and application, and belongs to the technical field of
biology. The
bifidobacterium longum subsp. Infantis CCFM1210 provided by the invention has the immunoregulation capability, and can improve the intestinal barrier and relieve
colitis. Animal experiments prove that through intervention of the
bifidobacterium longum subsp.infantis CCFM1210,
tissue damage of a mouse can be remarkably relieved, the
myeloperoxidase level can be remarkably reduced, the content of
tight junction protein in
colon tissue can be remarkably increased, the levels of proinflammatory cytokines IL-1beta and IL-6 can be remarkably reduced, and the level of an anti-inflammatory
cytokine IL-10 can be remarkably increased; the concentration of
butyric acid is obviously increased, the diversity of intestinal
flora is obviously improved, and the disorder of the
flora is relieved. Compared with a
traditional medicine for treating
colitis, a
medicine or a
probiotic preparation prepared from the
bifidobacterium longum subsp. Infantis CCFM1210 disclosed by the invention has certain advantages and has a wide market prospect.