64results about How to "Prevent and reduce incidence" patented technology

A system for providing medical device with anti-microbial properties to prevent infections. The system includes a medical device having a portion for insertion into the body of a patient, a lumen, and a substrate comprising an anti-microbial agent to be inserted into the lumen of the medical device. To protect the substrate from anti-microbial agents during insertion into the lumen, the system further includes a collapsible cover connected to the substrate. A connector can be used for attaching the substrate to the cover. The substrate may be an iodine-based rod. A guidewire may be attached to the connector to further facilitate insertion of the substrate into the lumen.

A system and method for performing a surgical procedure that are based on delivering air to a surgical site to prevent contamination of a wound or surgical instrument. A curtain of air above the surgical site prevents pathogens or pathogen laden particulates eminating from sources such as the skin of health care professionals including operating room staff, room air, and ceiling from contaminating the surgical site. The curtain of air may be turbulent or laminar and heated or humidified with a solution of anti-microbial agent such as an antibiotic or anti-microbial such as triclosan. Optional incorporation of a UV or blue light source into the system may also prevent infection. The system is designed to be ergonomically compatible with existing surgical substrates such as a retractor, bed, or drape. Sources of sterile air can be brought to a manifold pivotably coupled to a shaft that is attached to a bedrail or instrument stand to deliver the air directly over a surgical site.

This invention relates to the field of cardiac disease. More specifically, the invention relates to methods using an NGF antagonist for treating and preventing cardiac arrhythmia and methods of preventing death due to cardiac arrhythmia.

An oral dosage form comprises cromolyn sodium (sodium or disodium cromoglycate), and an acylated amino acid delivery agent.

The invention relates to a form of a passive or active annunciator that solves the problem of reminding a caregiver to reposition a patient at risk for aspiration usually located in an adjustable bed to some predetermined angular position. The annunciator may take the form of an inclinometer (100) that measures the angle of the bed (160) relative to a local gravity reference or a goniometer that measures the angle between the horizontal (140) and elevated portions (130) of the bed. The invention reminds the caregiver of the patient at risk for aspiration to maintain or reestablish the elevation of the torso of the patient at risk for aspiration to at least 30 degrees up to 45 degrees above the local horizontal to prevent or reduce the incidence of aspiration.

A method of treating neurological condition in a subject by administration of an extract, or fraction or sub-fraction thereof, of Nerium species or Thevetia species is provided, wherein the extract, or fraction or sub-fraction thereof, excludes oleandrin and neriifolin. Alzheimer's disease, Huntington's disease or stroke are treated by administering a therapeutically effective amount of the extract, or a fraction or sub-fraction thereof, to a subject. The extract can be present in a pharmaceutical composition.

A method of treating neurological condition in a subject by administration of a cardiac glycoside is provided. Alzheimer's disease, Huntington's disease or stroke are treated by administering a therapeutically effective amount of cardiac glycoside to a subject. The cardiac glycoside can be present in a dosage form.

The present invention provides methods for preventing colon cancer by administering, to a patient in need thereof, a polymeric proanthocyanidin composition from a Croton species or Calophyllum species in an amount sufficient to prevent colon cancer, which composition inhibits COX-2. The present invention also provides methods for treating inflammation locally in the intestines comprising administering to a patient in need thereof, a polymeric proanthocyanidin composition from a Croton species or Calophyllum species in an amount sufficient to treat inflammation. In one embodiment, the polymeric proanthocyanidin compound is crofelemer. The present invention in alternative embodiments provides methods for treating pain locally in the intestines and treating inflammatory bowel diseases, such as Crohn's disease and ulcerative colitis, as well as for treating familial adenomatous polyposis (FAP).

A light sensing circuit using an oxide semiconductor transistor, a method of manufacturing the light sensing circuit, and an optical touch panel including the light sensing circuit. Because the light sensing circuit includes only one light sensor transistor and one switch transistor formed on the same substrate, a structure of the light sensing circuit is simplified. Furthermore, because the light sensor transistor and the switch transistor have the same structure, a method of manufacturing the light sensing circuit is also simplified. Also, since an optical touch panel or an image acquisition apparatus using the light sensing circuit uses the light sensing circuit having a simple structure and does not use a capacitor, the optical touch panel or the image acquisition apparatus may be made thinner and larger.

A medical device with anti-microbial properties to prevent infections. This medical device, such as an in-dwelling catheter, has a portion that is insertable into the body of a patient and accessible from outside the body once the portion is inserted. The portion has an outer wall, a first active lumen within the outer wall, and a false lumen within the outer wall in which the false lumen has a distal portion and a proximal portion. The false lumen contains an anti-microbial agent that provides the outer wall with anti-microbial properties. The distal portion of the false lumen is sealed. The false lumen may be adjacent to the first active lumen. The medical device may also contain a second active lumen, wherein the first active lumen is an inlet lumen and the second active lumen is an outlet lumen. Alternatively, the false lumen may surround the first active lumen.

Devices, kits and methods described herein may be for treatment to skin, including but not limited to wound healing, the treatment, amelioration, and / or prevention of scars or keloids. A book-like packaging, applicator and / or tensioning device may be used to apply a dressing to a subject. The packaging, applicator and / or tensioning device may apply and / or maintain a strain in an elastic dressing.

A mobile communication terminal equipped with speaker phone functionality and a method for removing feedback when the speaker phone is in use are disclosed. The mobile communication terminal includes: a first voice input path serving as a default voice input path; a second voice input path serving as an additional voice input path; and a controller for determining whether a speaker phone is in use, wherein the controller selects one of the first and second voice input paths according to whether the speaker phone is in use.

This present invention provides a therapeutic composition for use in the treatment of mucositis and a method for using such a therapeutic composition. The therapeutic composition includes a pharmaceutical substance effective for treating mucositis formulated with a biocompatible polymer, such as a biocompatible reverse-thermal gelation polymer.

Topical application of a pharmacologically-inactive, inert polymeric solution to teeth affords a temporary, protective barrier for pharmacologically-active compounds that have been previously applied topically to the tooth surfaces for caries reduction. In a method of use, an aqueous dispersion polymethylmethacrylate (PMMA) and a suitable plasticizer are applied topically to the tooth surface immediately after the topical application of chlorhexidine or fluoride. The inert coating thus formed is distinct from any pharmacologically-active substance, and remains on the tooth surface until abraded by the chewing of hard foods. In a composition of matter, the solution contains ammonio methacrylate copolymer, type B USP / NF of between 20% and 35% w / w; triethyl citrate USP / NF of between 1% and 10% w / w; and purified water of between 60% and 70% w / w. The ammonio methacrylate copolymer is preferably EUDRAGIT RS 30 D brand available form Rohm GmbH.

Devices, kits and methods described herein may be for treatment to skin, including but not limited to wound healing, the treatment, amelioration, and / or prevention of scars or keloids. An applicator and / or tensioning device may be used to apply a dressing to a subject. The applicator and / or tensioning device applies and / or maintains a strain in an elastic dressing, wherein at least some of the strain is out-of-plane or at a non-orthogonal, non-parallel and non-aligned orientation to other strains in the dressing.

An insert for a bed facilitates use of a mattress having one cross-sectional profile with a bed frame having a different cross-sectional profile. An insert includes a base extending between sidewalls which have various contoured surfaces. The contoured sidewall surfaces enable the insert to be disposed in a bed frame in association with a mattress. Inner surfaces of the sidewalls are configured to accommodate receipt of a mattress while outer surfaces of the sidewalls are configured for the insert to be disposed in a bed frame. The surface sidewalls may further be configured to provide the insert with a safety feature which prevents or reduces the likelihood of a user falling from the side of a mattress associated with the insert.

The present invention provides for methods, processes and platforms to validate systems genetics networks to define their genetic regulators and to optimize translational applicability to humans for drug development. These systems genetics networks are sets of genes with a common function that demonstrate covariate expression that is genetically modulated by linked function network regulators (LFNRs) which comprise eQTLs in animals and GWAS SNPs in humans. LFNRs represent a new class of targets to identify drugs to prevent, ameliorate, and / or treat human diseases. LFNRs for the cell cycle-mitosis network have potential to be especially useful for anti-cancer therapies. The present invention provides for a drug that targets a specific LFNR for the cell cycle-mitosis network in Caucasian male liver to prevent the development of hepatocellular carcinoma in high risk patient populations.

A method of treating neurological condition in a subject by administration of a cardiac glycoside is provided. Alzheimer's disease, Huntington's disease or stroke are treated by administering a therapeutically effective amount of cardiac glycoside, and optionally triterpene(s), to a subject. The cardiac glycoside can be present in a dosage form.

Implementations of the present invention relate to systems, methods, and apparatus for constructing a building. More specifically, the present disclosure provides an interlocking wall system that can allow a builder to accurately position, orient, and / or secure various structural wall modules. Additionally, this disclosure provides systems and methods for securing one or more cladding layers to the building's envelope. Furthermore, implementations of the present disclosure can allow for quick and modifiable installation of utility and communication lines within the building.