The invention belongs to the medicine field and particularly relates to a medicament composition for reducing swelling and relieving pain, as well as the preparation and the application thereof. The technical problem to be solved is to provide a novel medicament composition for treating injuries from falls, fractures, contusions and strains, which has the obvious effects of promoting blood circulation, promoting the circulation of Qi, relieving pain and reducing swelling. The medicament composition comprises the following active components by weight part: 10 to 30 parts of dahurian angelica root, 20 to 60 parts of betilla striata, 20 to 60 parts of grassleaf sweelflag rhizome and 10 to 30 parts of dandelion, as well as 10 to 30 parts of kusnezoff monkshood, 10 to 30 parts of folium eriobotryae and 10 to 30 parts of radix paeoniae rubrathe root of common peony. The medicament composition is available for external administration after pulverizing the active components and harmonizing byhoney. The preparation method is convenient, the administration is simple, and the medicament composition can treat ligament injury, muscle injury, hematoma, joint swelling and thermalgia caused by injuries from falls, fractures, contusions and strains. The medicament composition has the advantages of short cure time, obvious effects and no recurrence, and provides a new option for the clinical treatment of injuries from falls, fractures, contusions and strains.