43 results about "Intensity modulate radiotherapy" patented technology

An apparatus for measuring absorption dose distribution may be used for radiotherapy, such as intensity modulated radiotherapy and radiosurgery. In the apparatus, measurement or evaluation of the distribution of the radiated dose within a phantom can be achieved accurately and in a relatively short length of time. The apparatus includes a phantom with a plastic plate scintillator having a thickness within the range of 0.15 to 1 mm and plastic blocks sandwiching the plastic scintillator, and an image analyzer. At least one of the plastic blocks is transparent and the image analyzer measures a pattern of intensity distribution of light emitted from the plastic scintillator when the phantom is irradiated.

A method for the optimization of radiation therapy treatment plans is disclosed. The disclosed method is equally-applicable to robotic radiosurgery as well as other types of radiosurgical delivery, intensity-modulated radiotherapy (IMRT), volumetric modulated arc therapy (VMAT), and three-dimensional conformal radiotherapy (3DCRT). A population-based heuristic approximation is used to perform a global search, and subsequently, a deterministic local trajectory search is employed to further refine the initial solution.

Provided is a conformal intensity-modulated radiation therapy device, comprising: a housing, formed with an accommodating space and a shielding cavity; shielding material, filled within the shielding cavity; a rotary source-carrying body, accommodated within the accommodating space; a shielding rod, accommodated within the rotary source-carrying body; a source body, accommodated at a bottom end of the shielding rod and used for carrying a radiation source; a first driving portion, arranged on the housing and driving the rotary source-carrying body to rotate around a rotary axis thereof so that the radiation source switches between an open source position and a closed source position; a pre-collimation body, arranged at an emission end of the radiation source and comprising a collimation hole, the collimation hole directly facing the radiation source when the radiation source is in the open source position; a shielding door, arranged at the side of the pre-collimation body away from the radiation source and directly facing the radiation source; a multi-leaf collimator, arranged outside the housing and directly facing the shielding door. Also provided is a conformal intensity-modulated radiation therapy system.

The invention provides a method for predicting the three-dimensional dose distribution of an intensity-modulated radiotherapy plan based on deep learning. The method includes: collecting effective intensity-modulated radiotherapy planning data to form a case database; extracting the three-dimensional anatomical structure contour features of each patient's region of interest from the case database; dividing the three-dimensional anatomical structure contour of the patient's region of interest into several binary Two-dimensional contour slice map; extract the dose characteristics of each patient from the case database, and divide it into several two-dimensional dose slice distribution maps; build a deep convolutional network, input the patient's two-dimensional contour slice map and the corresponding two-dimensional dose slice distribution Figure, the association model between anatomical structure contour features and dose features is obtained through model training; the three-dimensional dose distribution of new patients is predicted using the trained association model. By using the method of the present invention, the correlation between anatomical structure features and dose features can be effectively obtained, and the accuracy of dose prediction can be improved.

The invention discloses a shooting method and validation for a validation film of intensity modulated radiation therapy. The method is characterized in that a therapeutic machine MV level image validation device is utilized, a shooting function is used, and a double-exposure, triple-exposure and multi-exposure imaging technology, a therapy interruption field joint technology and a single-frame continuous collection mode are adopted; first, through common confirmation of a physician and a doctor, a therapy plan of a patient is transmitted to an image guide system; points are marked on surface of skin according to three-dimensional coordinate values given by a system in first-time body position arrangement and then triple- or multi-exposure imaging technology is adopted; then a sub field shape is formed by adopting the therapy interruption field joint technology and validation film image information is stored. According to the invention, a problem of a conventional method that a validation film in the actual treatment angle in intensity modulated radiation therapy cannot be acquired is solved, the neighboring relation between the field shape and the exposure range and normal tissuesis confirmed, and the invention has advantages of being accurate in positioning and causing less pain of patients.

The invention discloses a collimator angle optimization method for a volumetric-modulated arc therapy plan. Patient-specific target region structure information is used to perform three-dimensional reconstruction on a target region in order to obtain the projection images of the target region at different frame angles, and segmented optimization of the complete arc according to the conformal indexes of the different collimator angles to the target region and pertinent optimization of the collimator angle of each arc segment are carried out to achieve the personalized dynamic collimator angleoptimization method for the volumetric-modulated arc therapy plan. The method can dynamically optimize the collimator angle according to the patient-specific target region information, so the manual participation degree and the degree of dependence of the plan quality on the artificial experience are reduced, the increase of the efficiency and the consistency of the plan design is facilitated, a specific optimal plan is designed for every patient, and the resulting dosimetric improvement can avoid unnecessary tumor control rate decline and normal tissue damages and improve the efficacy of clinical radiotherapy.

The invention discloses an intensity-modulated radiation therapy plan optimization method based on predictive dose distribution guidance and application thereof. The method includes the steps of: inputting geometric anatomical structural features of a region of interest of a patient into a trained neural network model so as to obtain three-dimensional dose distribution prediction that endangers anorgan; establishing a field intensity distribution model by taking the three-dimensional dose distribution prediction as optimization guide, wherein an optimization objective function of the field intensity distribution model comprises a target item based on the three-dimensional dose distribution prediction and a target item based on equivalent volume dose; and setting relevant parameters basedon the optimization objective function and performing solution to obtain an intensity-modulated radiation therapy optimization plan. According to the invention, the predicted three-dimensional dose distribution is utilized to guide the optimization of the intensity-modulated radiation therapy plan, so that the individual optimization and the voxel-level precise dose optimization can be realized. According to the invention, the equivalent volume target is constructed to compensate the influence of a loose prediction error on a guidance optimization result, a wider solution space is provided atthe same time, and the advancing direction of plan optimization is ensured.