199 results about "Bacterial spore" patented technology

Sterilization methods and apparatus are effective to achieve a 6-log reduction in CFUs of industry standard bacteria and bacterial spores, i.e., B. stearothermophilus and B. subtilis spores, by subjecting sterilizable materials to a chemical additive-containing carbon dioxide sterilant fluid at or near its supercritical pressure and temperature conditions. Most preferably, the chemical additive-containing supercritical carbon dioxide sterilant fluid is agitated during sterilization, e.g., via mechanical agitation or via pressure cycling.

This invention describes a rapid (10 to 15 minutes), simple, flexible and efficient method of nucleic acids extraction for nucleic acid testing assays. This method has the following basic steps: i) mechanical cell lysis using solid particles in the presence of a chelating agent, followed by ii) controlling the presence and / or activity of NAT assays inhibitors. This method is applicable to various biological samples and universal for microorganisms, as one can use it to extract nucleic acids from test samples containing target viruses, bacteria, bacterial spores, fungi, parasites or other eukaryotic cells, including animal and human cells.

The present invention relates to electrochemically treated water, obtainable by means of a method that is characterized by the following steps: a) electrolyzing water and b) reducing the concentrations of the oxidants created in step a). The electrochemically treated water obtained in this manner is characterized by a disinfecting effect on bacteria, bacterial spores, fungi, fungal spores, viruses, prions, or mixtures thereof. The invention further relates to water, characterized in that the same has a disinfecting effect on bacteria, bacterial spores, fungi, fungal spores, viruses, algae, prions, or mixtures thereof, that it is substantially free of disinfection agents with the exception of the oxidants related to the disinfection agents, and that it has a total concentration of oxidants of less than 20 ppm.

The invention relates to a method for inhibiting bacterial spores from becoming infectious vegetative cells in a mammal in need thereof. In another embodiment, invention relates to a method for inhibiting outgrowth of bacterial spores in a mammal in need thereof. The method comprises administering to the mammal an effective amount of a non-antibacterial tetracycline formulation. In one embodiment, the non-antibacterial tetracycline formulation comprises an antibacterial tetracycline in a sub-antibacterial amount. In another embodiment, the non-antibacterial tetracycline formulation comprises a non-antibacterial tetracycline.

The present invention includes a method and apparatus for the detection of a target material. The method and apparatus includes providing a substrate with a surface and forming a domains of deposited materials thereon. The deposited material can be placed on the surface and bound directly and non-specifically to the surface, or it may be specifically or non-specifically bound to the surface. The deposited material has an affinity for a specific target material. The domains thus created are termed affinity domains or deposition domains. Multiple affinity domains of deposited materials can be deposited on a single surface, creating a plurality of specific binding affinity domains for a plurality of target materials. Target materials may include, for example, pathogens or pathogenic markers such as viruses, bacteria, bacterial spores, parasites, prions, fungi, mold or pollen spores. The device thus created is incubated with a test solution, gas or other supporting environment suspected of containing one or more of the target materials. Specific binding interactions between the target materials and a particular affinity domain occurs and is detected by various methods.

Devices and methods for thermally lysing of biological material, for example vegetative bacterial cells and bacterial spores, are provided. Hot solution methods for solubilizing bacterial spores are described. Systems for direct analysis are disclosed including thermal lysers coupled to sample preparation stations. Integrated systems capable of performing sample lysis, labeling and protein fingerprint analysis of biological material, for example, vegetative bacterial cells, bacterial spores and viruses are provided.

A novel biological indicator system to detect the effectiveness of a sterilization treatment and methods for assessing the viability of and / or changes in bacterial spores exposed to a sterilization or disinfection method by multiangle light scattering thereby detecting a change in the spores as indicators of spore viability and the efficacy of the sterilization or disinfection method.

The present invention relates the use photosensitizers to inactivate bacterial spores of bacterial species including Bacillus anthracis. Methods of the present invention are useful in the decontamination and treatment of living animals and in the decontamination of inanimate objects and substances.

The invention discloses a microbial seal-healing capsule for coal mine air leakage plugging as well as a preparation method and application of the microbial seal-healing capsule. Dry powder of bacterial spores is uniformly dispersed in water, a suitable substrate is selected according to the kinds of the bacterial spores, the substrate is added into a uniformly-dispersed mixed solution according to a certain ratio of the bacterial spores to the substrate and is uniformly stirred to be agglomerated, the agglomerated mixture is slowly added into a multifunctional granulator and is extruded, a cooling system is started, the temperature of the material is maintained, and the extruded strip-shaped substance is added into a rounder for rounding and is sieved and dried to obtain microparticles; and the microbial seal-healing capsule is prepared from the microparticles and a wall material by using a vacuum impregnation method or an interfacial polymerization method, the microbial seal-healingcapsule and a main material for air leakage plugging are mixed to be used, once concrete is cracked, the spores inside the material can be activated to normally metabolize, and calcium carbonate is continuously induced to be precipitated, so that the self-repair of cracks is realized.

A novel biological indicator system to detect the effectiveness of a sterilization treatment and methods for assessing the viability of and / or changes in bacterial spores exposed to a sterilization or disinfection method by multiangle light scattering thereby detecting a change in the spores as indicators of spore viability and the efficacy of the sterilization or disinfection method.

The present invention relates generally to chemical and biological decontamination solutions and methods of using them. The invention is useful for decontaminating a wide range of compounds and organisms. In particular, the systems, methods, solutions, and formulations of the invention can be used to remove and / or neutralize organophosphates and other toxic chemicals, bacteria, bacterial spores, fungi, molds and viruses.

The present invention relates to a method for expressing a target protein on an exosporium forming the outermost surface of bacterial spores. More particularly, the present invention relates to a method for expressing a target protein on the surface of cells and spores using an exosporium as a matrix for surface expression, and methods for the production of a protein array, the production of antibodies, the separation of a certain substance from a mixture, bioconversion, and the improvement of a target protein, which are characterized by using the cells or spores having the target protein that was expressed on the surface by the above expression method. The method for expressing the target protein on the surface of the spore outer membrane of the gene carriers according to the present invention has effects in that a variety of the target proteins can be expressed and the level of surface expression of the target protein is increased compared to the existing technology, and also the structural stability of the gene carriers having the target protein expressed on their surface, the viability of the host, and the rapidity of the screening method, are greatly increased.

A method and an apparatus for detecting and quantifying bacterial spores on a surface. In accordance with the method: bacterial spores are transferred from a place of origin to a test surface, the test surface comprises lanthanide ions. Aromatic molecules are released from the bacterial spores; a complex of the lanthanide ions and aromatic molecules is formed on the test surface, the complex is excited to generate a characteristic luminescence on the test surface; the luminescence on the test surface is detected and quantified.

A method and an apparatus for detecting and quantifying bacterial spores on a surface. In accordance with the method: a matrix including lanthanide ions is provided on the surface containing the bacterial spores; functionalized aromatic molecules are released from the bacterial spores on the surface; a complex of the lanthanide ion and the aromatic molecule is formed on the surface; the complex of the lanthanide ion and the aromatic molecule is excited to generate a characteristic luminescence of the complex on the surface; and the bacterial spores exhibiting the luminescence of the complex on the surface are detected and quantified.