The invention discloses a glass test tube high-temperature drying and disinfection device. The glass test tube high-temperature drying and disinfection device comprises a box body, a clapboard, dryingbars, a ventilation pipe, hot air circulating devices and a control device, wherein the box body is internally provided with the clapboard, the clapboard is provided with the drying bars, the bottomends of the drying bars are connected with the ventilation pipe, the ventilation pipe penetrates through the clapboard to be connected with one of the hot air circulating devices arranged below the clapboard inside the box body, the position, located below the clapboard, inside the box body is further provided with the control device, the control device is in electrical connection with the hot aircirculating devices, each drying bar is internally hollow and provided with a cavity to communicate with the ventilation pipe, and the side wall of each drying bar is further provided with a plurality of ventilation holes. By means of the glass test tube high-temperature drying and disinfection device, rapid and effective drying and disinfection can be performed on the inner portions of test tubes, the inner portions of the test tubes are heated evenly, and meanwhile, water accumulation and residue of the inner portions of the test tubes can be prevented.