The invention relates to a detecting circuit for heart sound pulse detection. The detecting circuit comprises a pre-amplification circuit and an isolated output circuit, the pre-amplification circuit comprises a first operational amplifier, a second operational amplifier, a first resistor, a second resistor, a third resistor, a fourth resistor, a fifth resistor, a first capacitor and a second capacitor, and the isolated output circuit comprises a first integrated circuit, a second integrated circuit, a sixth resistor, a seventh resistor, an eighth resistor and a ninth resistor. According to the detecting circuit for heart sound and pulse detection, a double operation-amplification compensation form is adopted for the pre-amplification circuit, a compensation function is achieved for temperature drift of an operational amplifier, therefore, the long-term stability of the circuit can be enhanced, and the detecting reliability of the circuit is improved well. According to the isolated output circuit, detected signals and an internal detecting circuit can be isolated through the isolating function of the first integrated circuit, therefore, the reliability of the isolated output circuit is improved, and heart sound pulses are reliably detected.