The invention discloses a novel environment-friendly refrigerant, which is formed by a first component, difluoromethane, penta-fluoroethane and hydrocarbon component, wherein the first component is one of fluoroethane and 1, 1-difluoroethane, hydrocarbon component is the combination of one or more than one of isobutene, normal butene, propane and propylene. The refrigerant whose ODP is zero, which does not damage atmospheric ozone layer, and largely reduces GWP value compared with HCFC-22 and current substitutes R407 C and R410A, and has excellent environment-friendly property. The refrigerant whose thermal property is equivalent to HCFC-22 can be directly used in a system which originally uses HCFC-22, can reduce charge amount and increase energy effect ratio, and has the advantages of saving resources and energy. The refrigerant can be used as long-term substitute of HCFC-22, which provides a reliable technology which is easy to be popularized and applied and can take effect rapidlyfor the global to cope with climate warming.