56results about How to "Efficient drug delivery" patented technology

The invention relates to a preparation method of a liposome and the liposome prepared by the preparation method. The preparation method of the liposome comprises the following steps: (1) respectively preparing a lipoid molecule solution and a guest molecule solution; and (2) mixing the mixed lipoid molecule solution prepared in step (1) with a host molecule solution, so as to obtain the liposome. The liposome obtained by the preparation method is a single-compartment liposome of which the particle size is distributed in the range of 15-100nm, especially, in the range of 20-80nm. The invention also provides a preparation method of a drug-carrying liposome as well as the drug-carrying liposome obtained by the preparation method. The liposome or the drug-carrying liposome prepared by the preparation method is small in particle size and narrow in distribution, so that the liposome drug can be more rapidly administered to the lesion to improve curative effect; moreover, the micro-particle-size liposome prepared by the preparation method is capable of reaching the inside of the tumor tissue where the regular liposome cannot reach. Furthermore, the in-vivo transport time of the liposome drug is shortened by the rapid administration of the liposome drug, so that the degradation loss of the liposome drug by the organism enzyme system and the immune system is further reduced so as to reduce the toxic and side effects.

The invention relates to the field of genetic engineering technologies, in particular to cytomembrane positioning signal peptide and coding sequence and application thereof. According to the cytomembrane positioning signal peptide and coding sequence and application, (a) or (b) serves as the signal peptide; (a) is polypeptide composed of an amino acid sequence as shown in a sequence 2 in a sequence table; (b) is derivative polypeptide with a cytomembrane positioning signal peptide function and formed by conducting replacing and / or deletion and / or adding of one or more amino acid residues on the amino acid sequence of the sequence 2. The signal peptide can locate target protein to the host cytomembrane. The cytomembrane positioning signal peptide and proper target protein form infused protein to be used for developing vaccine and medicine for treating virus, parasites and bacterial infection and achieve efficient dosing.

A dripping pill of oleanolic acid for treating chronic metastatic hepatitis features high natural level and safety and low toxic by-effect. Its preparing process is also disclosed.

A medical composition for treating diarrhea is prepared from the extracts of coptis root and magnolia bark, aucklandia root oil and the oil of dried ginger.

The invention discloses a drug-supplying device for a respiratory medicine department. The drug-supplying device structurally comprises a liquid drug container, a container shell, a plastic shell, a control knob, a suction port and a plastic fixed seat. The control knob and the suction port are pushed out of a mechanism by retraction, the control knob controls a third transmission gear to rotate,the third transmission gear drives a second belt pulley in transmission and drives a meshing gear to rotate, a drug-supplying inner tube is pushed out in horizontal movement, protection of a traditional cover can be omitted by the design of free retraction, the control knob is turned to push out the suction port when needed, the control knob is turned anticlockwise to feed the suction port when not needed, manufacturing cost is reduced under the condition of convenient operation, and the drug-supplying device is high in practicability.

A dripping pill of fibrauretin for treating infilammation features high natural level and safety and low toxic by-effect. Its preparing process is also disclosed.

A dripping pill for treating vasculitis, cerebral thrombus, and their sequelae features high natural level and safety and low toxic by-effect. Its preparing process is also disclosed.

A dripping pill of agrimophol for treating filariasis and trichomoniasis features high natural level and safety and low toxic by-effect. Its preparing process is also disclosed.

A dripping pill of asiaticoside for treating wound features high natural level and safety and low toxic by-effect. Its preparing process is also disclosed.