41results about How to "Designed for such use" patented technology

Disclosed are methods to identify an agent which may modulate resistance to HIV-1-mediated disease, comprising contacting at least one agent to be tested with a cell comprising human ICAM-1, and detecting the cell's resistance to HIV-1 viral replication, propagation, or function, wherein an agent is identified by its ability to increase the cell's resistance to HIV-1 viral replication, propagation, or function. Also disclosed are human mutant ICAM-1 polypeptides and methods to treat HIV-1 viral replication, propagation, or function in a human subject by ICAM-1 gene therapy relating to one or more of the following 10 mutations to human ICAM-1: L18Q, K29D, P45G, R49W, E171Q, wherein the mutant ICAM-1 is otherwise identical to human ICAM-1.

A wind turbine with a tower, a nacelle, a main shaft, a hub and blades is provided. The wind turbine also includes a liquid medium distribution system for transport of liquid medium in the wind turbine. The liquid medium distribution system has a first distribution sub-system located in the tower, a second distribution sub-system located in the nacelle, a third distribution sub-system located in the hub, a tower-nacelle-interface connecting the first distribution sub-system to the second distribution sub-system, and a nacelle-hub-interface connecting the second distribution sub-system to the third distribution sub-system. Further, a method of transporting liquid medium in a wind turbine is provided.

The present invention includes fluid control systems employing compliant electroactive materials.

A programmable logic device architecture. This programmable logic architecture includes a first logic block (425) containing programmable logic elements for performing logic functions. The architecture may also include a diagnostic block interface (415), which interfaces with the first logic block (425), for performing JTAG functions, configuring the first logic block (425), initializing the first logic block (425), interfacing with off-chip diagnostic and test devices and equipment, and performing other similar functions. The first logic block (425) may be programmably coupled to other components on the integrated circuit using a first programmable interconnect network (511). The first logic block (425) includes a plurality of second logic blocks (505) which may be programmably coupled using a second programmable interconnect network (521). The second programmable interconnect network (521) may be programmably coupled to the first programmable interconnect network (511). Furthermore, the plurality of second logic blocks (505) include a plurality of third logic blocks (525) which may be programmably coupled using a third programmable interconnect network (535). A signal from a third logic block (525) may be programmably coupled to the other logic blocks, the diagnostic block interface (415), and other circuitry on the integrated circuit. The internal circuitry of these logic blocks may be monitored through a variety of programmable interconnect paths. This architecture is useful when debugging a design, especially for emulation and prototyping applications.

The invention relates to derivative compounds of partially-reduced isoquinoline with substitution of a sec-butyl group at position 3 with calpain inhibitor activity. The inventive compound comprises an ester or amide derived from (3-sec-butyl-1-oxo-2,3-dihydro-1H-isoquinolin-4-yliden)-acetic acid and (3-sec-butyl-1-thioxo-2, 3-dihydro-1H-isoquinolin-4-yliden)-acetic acid. Compounds having formula I or II can be used in the preventive or therapeutic treatment of a degenerative disease.

The present invention provides multilayer polymer films, materials and coatings which exhibit robust underwater superoleophobicity and have remarkable structural functional tolerance to a broad range of physical, chemical, and environmental challenges encountered by surfaces deployed in aqueous or aquatic environments. These materials can be fabricated on surfaces of arbitrary shape, size, and composition and provide straightforward means to manipulate surface chemistry and fine-tune other useful features of the interfacial behavior (e.g., underwater oil-adhesiveness). These materials address key obstacles to the application of non-wetting surfaces and anti-fouling ‘super-phobic’ materials in practical, real-world scenarios.

A wind turbine with a tower, a nacelle, a main shaft, a hub and blades is provided. The wind turbine also includes a liquid medium distribution system for transport of liquid medium in the wind turbine. The liquid medium distribution system has a first distribution sub-system located in the tower, a second distribution sub-system located in the nacelle, a third distribution sub-system located in the hub, a tower-nacelle-interface connecting the first distribution sub-system to the second distribution sub-system, and a nacelle-hub-interface connecting the second distribution sub-system to the third distribution sub-system. Further, a method of transporting liquid medium in a wind turbine is provided.

While a base model has been determined for a product, in a system for performing a configuration designing operation of the product by setting a specification value to a specification item of the product, a product configuration design aiding system aids that a configuration designer can easily perform the configuration designing operation while following a restriction condition of a specification value of a specification item. A specification configuration information database is constructed which describes restriction conditions available for the specification values with respect to the specification item, and a configuration designing screen for inputting the specification values with respect to the specification item is displayed so as to conduct an input by the configuration designer.

A keypad assembly for a portable terminal includes a first keypad assembly including a substrate formed with openings, and a second keypad assembly including a stick which extends through the substrate. The stick is substantially coplanar with keys on the first keypad.

A broadband Green's function computation technique that employs low wavenumber extraction on a modal summation is used to model the waveguide behavior of electronic components, systems, and interconnects on a printed circuit board. Use of the broadband technique permits discretizing the surface of the printed circuit board across a wide range of frequencies all at once. The broadband Green's function is also extended to via waveguides on circuit boards and power / ground plane waveguides of arbitrary shape. Such a method can analyze a given circuit board geometry over a broad frequency range several hundred times faster than is otherwise possible with existing commercial analysis tools. The present method is useful in electronic design automation for analyzing signal integrity and power integrity, reducing electromagnetic interference and ensuring electromagnetic compatibility.

A method for producing a single crystal by Czochralski method with pulling a seed crystal from a raw material melt, wherein in which a range of a pulling rate of pulling a single crystal, a temperature gradient at a solid-liquid interface and a highest temperature at an interface between a crucible and a raw material melt are defined. The single crystal is pulled with controlling the pulling rate and / or the temperature gradient at a solid-liquid interface within the determined range. The method produces a single crystal in which a desired defect region and / or a desired defect-free region can be determined more precisely and a single crystal with desired quality can be more surely pulled.

An off-highway vehicle has a front chassis portion, a rear chassis portion, a front ground drive system and a rear ground drive system. The front chassis portion has a front axle assembly having a front axle housing and a front axle shaft carrying a front wheel hub. The rear chassis portion has a rear axle assembly including a rear axle housing and a rear axle shaft carrying a rear wheel hub. The front ground drive system includes a front drive wheel mounted to the front wheel hub, a front idler wheel mounted to the front axle housing via a front drive frame member in front of the front drive wheel. The rear ground drive system has a rear drive wheel mounted to the rear wheel hub, a rear idler wheel mounted to the rear axle housing via a rear frame member behind the rear drive wheel.

The present invention provides multilayer polymer films, materials and coatings which exhibit robust underwater superoleophobicity and have remarkable structural functional tolerance to a broad range of physical, chemical, and environmental challenges encountered by surfaces deployed in aqueous or aquatic environments. These materials can be fabricated on surfaces of arbitrary shape, size, and composition and provide straightforward means to manipulate surface chemistry and fine-tune other useful features of the interfacial behavior (e.g., underwater oil-adhesiveness). These materials address key obstacles to the application of non-wetting surfaces and anti-fouling ‘super-phobic’ materials in practical, real-world scenarios.