Sensors (10, 110, 210, 310, 410) and a method for detecting an
analyte are described. Sensors (10, 110, 210, 310, 410) each have a volume of a hydrophilic medium (24) that retains an amount of
analyte proportionate to the concentration of
analyte in a
biological fluid, electrodes (12) and a
redox enzyme in contact with medium (24), and an
electron transfer
mediator. The fluid contacts sensors (10, 110, 210, 310, 410) and at initially predetermined intervals intermittently applies a potential to
electrode (12) sufficient to oxidize the
mediator and sensing current through
electrode (12) as a function of the duration of the
applied potential. The applied
mediator oxidizing
applied potential is maintained for a period of time sufficient to determine the rate of change of current with time through
electrode (12). The current flow is correlated with the current flow for known concentrations of the analyte in medium (24).