The invention discloses a grape grafting and cultivating method. The method comprises the steps of (1) selection of stocks, (2) grafting method, (3) binding and (4) grafting management after grafting planting, in the step of the selection of stocks, resistant North America species and its cohybridization generation or local wild grape vines are selected as stocks; the grafting method is divided into open field local grafting and indoor grafting; in the step of binding, soybean cake powder, microelement (iron, sulfur, copper, manganese and selenium) and water are mixed into thick mud, the mixture is smeared on gauze or cotton cloths, and the gauze or the cotton cloths containing the thick nutrient mud is bound on joints of stocks and scions. According to the grape grafting and cultivating method, the method solves the problems that conventional hard branch top grafting influences healing of connectors due to wounds, the growing period after surviving is short, growth is weak, and the flower forming and fruiting rate of a second year is low, the survival rate of grape grafting is improved and reaches 90%, fruit forming amount is large, fruits have abundant nutrient, fresh color and good taste.